Zobrazeno 1 - 10
of 191
pro vyhledávání: '"David R Booth"'
Autor:
Scott A Read, Enoch S Tay, Mahsa Shahidi, Kate S O'Connor, David R Booth, Jacob George, Mark W Douglas
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136227 (2015)
Treatment of chronic hepatitis C virus (HCV) infection is evolving rapidly with the development of novel direct acting antivirals (DAAs), however viral clearance remains intimately linked to the hepatic innate immune system. Patients demonstrating a
Externí odkaz:
https://doaj.org/article/08fc8a2c46fb49bf9fb285b8a0859a8e
Autor:
Fiona C McKay, Edwin Hoe, Grant Parnell, Prudence Gatt, Stephen D Schibeci, Graeme J Stewart, David R Booth
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77508 (2013)
The IL7Rα gene is unequivocally associated with susceptibility to multiple sclerosis (MS). Haplotype 2 (Hap 2) confers protection from MS, and T cells and dendritic cells (DCs) of Hap 2 exhibit reduced splicing of exon 6, resulting in production of
Externí odkaz:
https://doaj.org/article/31ed427fd32c4fc3be012982a02f12e8
Autor:
Vijayaprakash Suppiah, Silvana Gaudieri, Nicola J Armstrong, Kate S O'Connor, Thomas Berg, Martin Weltman, Maria Lorena Abate, Ulrich Spengler, Margaret Bassendine, Gregory J Dore, William L Irving, Elizabeth Powell, Margaret Hellard, Stephen Riordan, Gail Matthews, David Sheridan, Jacob Nattermann, Antonina Smedile, Tobias Müller, Emma Hammond, David Dunn, Francesco Negro, Pierre-Yves Bochud, Simon Mallal, Golo Ahlenstiel, Graeme J Stewart, Jacob George, David R Booth, International Hepatitis C Genetics Consortium (IHCGC)
Publikováno v:
PLoS Medicine, Vol 8, Iss 9, p e1001092 (2011)
BackgroundTo date, drug response genes have not proved as useful in clinical practice as was anticipated at the start of the genomic era. An exception is in the treatment of chronic hepatitis C virus (HCV) genotype 1 infection with pegylated interfer
Externí odkaz:
https://doaj.org/article/35e1fae1f2ff4e0fbdcb58e851dcbeeb
Autor:
Carlos Riveros, Drew Mellor, Kaushal S Gandhi, Fiona C McKay, Mathew B Cox, Regina Berretta, S Yahya Vaezpour, Mario Inostroza-Ponta, Simon A Broadley, Robert N Heard, Stephen Vucic, Graeme J Stewart, David W Williams, Rodney J Scott, Jeanette Lechner-Scott, David R Booth, Pablo Moscato, ANZgene Multiple Sclerosis Genetics Consortium
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14176 (2010)
BackgroundSeveral lines of evidence suggest that transcription factors are involved in the pathogenesis of Multiple Sclerosis (MS) but complete mapping of the whole network has been elusive. One of the reasons is that there are several clinical subty
Externí odkaz:
https://doaj.org/article/57cf07fc99e548b88dcd763073a08da1
Autor:
Judith Field, Sharon R Browning, Laura J Johnson, Patrick Danoy, Michael D Varney, Brian D Tait, Kaushal S Gandhi, Jac C Charlesworth, Robert N Heard, Australia and New Zealand Multiple Sclerosis Genetics Consortium, Graeme J Stewart, Trevor J Kilpatrick, Simon J Foote, Melanie Bahlo, Helmut Butzkueven, James Wiley, David R Booth, Bruce V Taylor, Matthew A Brown, Justin P Rubio, Jim Stankovich
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13454 (2010)
We conducted an association study across the human leukocyte antigen (HLA) complex to identify loci associated with multiple sclerosis (MS). Comparing 1927 SNPs in 1618 MS cases and 3413 controls of European ancestry, we identified seven SNPs that we
Externí odkaz:
https://doaj.org/article/666c12ee17314e0d830ff51e46de6064
Autor:
Mathew B Cox, Murray J Cairns, Kaushal S Gandhi, Adam P Carroll, Sophia Moscovis, Graeme J Stewart, Simon Broadley, Rodney J Scott, David R Booth, Jeannette Lechner-Scott, ANZgene Multiple Sclerosis Genetics Consortium
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12132 (2010)
It is well established that Multiple Sclerosis (MS) is an immune mediated disease. Little is known about what drives the differential control of the immune system in MS patients compared to unaffected individuals. MicroRNAs (miRNAs) are small non-cod
Externí odkaz:
https://doaj.org/article/08421e7245d1407d9ac2d8dacc401bf5
Autor:
Kaushal S Gandhi, Fiona C McKay, Eve Diefenbach, Ben Crossett, Stephen D Schibeci, Robert N Heard, Graeme J Stewart, David R Booth, Jonathan W Arthur
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10484 (2010)
Interferon beta (IFNbeta) is the most common immunomodulatory treatment for relapsing-remitting multiple sclerosis (RRMS). However, some patients fail to respond to treatment. In this study, we identified putative clinical response markers in the ser
Externí odkaz:
https://doaj.org/article/8c6ea329e8b54c66ae614ed5dc5195ca
Autor:
David Brown, Prudence N. Gatt, Graeme J. Stewart, Steve Vucic, Fiona C. McKay, Christopher Liddle, Samantha P L Law, Scott N. Byrne, Prue H. Hart, David R. Booth, Stephen D. Schibeci, Grant P Parnell
Publikováno v:
Genes and Immunity
Although genetic and epidemiological evidence indicates vitamin D insufficiency contributes to multiple sclerosis (MS), and serum levels of vitamin D increase on treatment with cholecalciferol, recent metanalyses indicate that this vitamin D form doe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82dcd9079bcb06a7e191eb8c74f83cde
http://europepmc.org/articles/PMC8387232
http://europepmc.org/articles/PMC8387232
Publikováno v:
Journal of Data Science. 13:473-494
This paper empirically investigates the impact of the government bailout on analysts' forecast optimism regardingfirms in the automotive industry. We compare the results fromM- and MM-robust methodologies to the results from OLS regression in an even
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fc2dda0b6194be7867105b2dbce2d59
https://doi.org/10.6339/jds.201507_13(3).0004
https://doi.org/10.6339/jds.201507_13(3).0004
Publikováno v:
Journal of Data Science. 9:607-623
In the face of global uncertainty and a growing reliance on third party indices to gain a snapshot of a country's operations, accurate decision making makes or breaks relationships in global trade. Under this aegis, we question the validity of tradit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f5f2be2a66581614f59562f0dfbbe90
https://doi.org/10.6339/jds.201110_09(4).0008
https://doi.org/10.6339/jds.201110_09(4).0008