Zobrazeno 1 - 10
of 29
pro vyhledávání: '"David R, Turton"'
Autor:
Chiara Da Pieve, Marta Costa Braga, David R. Turton, Frank A. Valla, Pinar Cakmak, Karl-Heinz Plate, Gabriela Kramer-Marek
Publikováno v:
Molecules, Vol 27, Iss 3, p 675 (2022)
A large number of applications for fibroblast activation protein inhibitors (FAPI)-based PET agents have been evaluated in conditions ranging from cancer to non-malignant diseases such as myocardial infarction. In particular, 68Ga-FAPI-46 was reporte
Externí odkaz:
https://doaj.org/article/c19d6928e7fb40ffa28ae8fed6f01334
Autor:
Eric O. Aboagye, Ramla O. Awais, Giampaolo Tomasi, Quang-Dé Nguyen, Frazer J. Twyman, Diana Brickute, Laurence Carroll, Graham Smith, David R. Turton, Israt S. Alam, Timothy H. Witney
PDF file - 474K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0032828844ef253937fe3601984d5042
https://doi.org/10.1158/1078-0432.22444166.v1
https://doi.org/10.1158/1078-0432.22444166.v1
Autor:
Eric O. Aboagye, Ramla O. Awais, Giampaolo Tomasi, Quang-Dé Nguyen, Frazer J. Twyman, Diana Brickute, Laurence Carroll, Graham Smith, David R. Turton, Israt S. Alam, Timothy H. Witney
Purpose:11C-Choline–positron emission tomography (PET) has been exploited to detect the aberrant choline metabolism in tumors. Radiolabeled choline uptake within the imaging time is primarily a function of transport, phosphorylation, and oxidation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d5a5954a50b69664ff40802d98be0dd
https://doi.org/10.1158/1078-0432.c.6520076
https://doi.org/10.1158/1078-0432.c.6520076
Autor:
Chiara, Da Pieve, Marta, Costa Braga, David R, Turton, Frank A, Valla, Pinar, Cakmak, Karl-Heinz, Plate, Gabriela, Kramer-Marek
Publikováno v:
Molecules (Basel, Switzerland). 27(3)
A large number of applications for fibroblast activation protein inhibitors (FAPI)-based PET agents have been evaluated in conditions ranging from cancer to non-malignant diseases such as myocardial infarction. In particular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::090150682487e5d9bc02ec9c576af104
https://pubmed.ncbi.nlm.nih.gov/35163938
https://pubmed.ncbi.nlm.nih.gov/35163938
Autor:
Thomas C. Wilson, Gabriela Kramer-Marek, Véronique Gouverneur, Stephen Turnock, Louis Chesler, David R Turton, Carlos D. Martins, Graham Smith
Publikováno v:
Scientific Reports
Targeted radiotherapy with 131I-mIBG, a substrate of the human norepinephrine transporter (NET-1), shows promising responses in heavily pre-treated neuroblastoma (NB) patients. Combinatorial approaches that enhance 131I-mIBG tumour uptake are of subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a2ab6ba248530a79f3354c5804e298
https://ora.ox.ac.uk/objects/uuid:15779b9f-d389-4f4a-9835-8e95a054eaa9
https://ora.ox.ac.uk/objects/uuid:15779b9f-d389-4f4a-9835-8e95a054eaa9
Autor:
Julius Leyton, Meg Perumal, Eric O. Aboagye, Sajinder K. Luthra, Bo Shan, David R. Turton, Graham Smith, Edward G. Robins, Yongjun Zhao, Quang-Dé Nguyen, Erik Årstad
Publikováno v:
Nuclear Medicine and Biology. 38:39-51
Choline radiotracers are widely used for clinical PET diagnosis in oncology. [(11)C]Choline finds particular utility in the imaging of brain and prostate tumor metabolic status, where 2-[(18)F]fluoro-2-deoxy-D-glucose ('FDG') shows high background up
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f49312236b87385854b5fd475fa2bdda
https://doi.org/10.1016/j.nucmedbio.2010.06.012
https://doi.org/10.1016/j.nucmedbio.2010.06.012
Autor:
Lula Rosso, Paul M. Grasby, Ella Hirani, Oliver D. Howes, Diana Brickute, David R. Turton, Rabia Ahmad, Sajinder K. Luthra, Alice Egerton
Publikováno v:
Synapse. 64:301-312
[(11)C]-(+)-PHNO is a new dopamine D(2/3) receptor agonist radiotracer which has been successfully used to measure D(2/3) receptor availability in experimental animals and man. Here we report in vivo evaluation in the rat of the biodistribution, meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c68ce6b11cb6ade1b81156d166411ea
https://doi.org/10.1002/syn.20718
https://doi.org/10.1002/syn.20718
Autor:
Andrew Constanti, Erik Årstad, Roberta Caruso, Lyn S. Pilowsky, Rosaria Gitto, S.P. Hume, David R. Turton, Rabia Ahmad, Alba Chimirri, Sajinder K. Luthra
Publikováno v:
Bioorganic & Medicinal Chemistry. 14:4712-4717
2-Acetyl-1-(4'-chlorophenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline, one of the most potent non-competitive AMPA antagonists described to date, has been labelled with carbon-11 and tritium and evaluated as a potential ligand for in vivo imaging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010472b7186582fb8449c50f3023681f
https://doi.org/10.1016/j.bmc.2006.03.034
https://doi.org/10.1016/j.bmc.2006.03.034
Autor:
David R. Turton, Sajinder K. Luthra, Yongjun Zhao, Erik Årstad, Frank Brady, Edward G. Robins
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 49:163-170
N-methyl-D-aspartate (NMDA) receptors play a key role in excitatory neurotransmission and are linked to a variety of acute and chronic neurodegenerative diseases including epilepsy, schizophrenia, Parkinson's disease and drug abuse. N-(2-chloro-5-met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25a8d0979373445a3b13ab0a8d4ae819
https://doi.org/10.1002/jlcr.1033
https://doi.org/10.1002/jlcr.1033
Publikováno v:
Applied Radiation and Isotopes. 48:917-924
Propionyl-L-carnitine (PLC) is under development as a therapeutic for the treatment of peripheral artery disease, coronary heart disease and chronic heart failure. Three methods were examined for labelling PLC in its propionyl group with positron-emi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c919bbf509b3c7545e6d83ddd73f7ba6
https://doi.org/10.1016/s0969-8043(97)00026-2
https://doi.org/10.1016/s0969-8043(97)00026-2