Zobrazeno 1 - 10
of 95
pro vyhledávání: '"David R, Pepperberg"'
Autor:
David R. Pepperberg
Publikováno v:
Journal of Alzheimer's Disease. 72:663-675
Cerebral hypoperfusion-induced hypoxia, a condition that impairs oxygen utilization and thus ATP production by mitochondrial oxidative phosphorylation (oxphos), is thought to contribute to neural degeneration in Alzheimer's disease. However, hypoxia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87654a6352753d1fca3e473ae84fd152
https://doi.org/10.3233/jad-190476
https://doi.org/10.3233/jad-190476
Autor:
Sujatha P Koduvayur, Hélène A Gussin, Rajni Parthasarathy, Zengping Hao, Brian K Kay, David R Pepperberg
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87964 (2014)
The abundance and physiological importance of GABAA receptors in the central nervous system make this neurotransmitter receptor an attractive target for localizing diagnostic and therapeutic biomolecules. GABAA receptors are expressed within the reti
Externí odkaz:
https://doaj.org/article/2e81072dc8494f7c8850776891cd5029
Autor:
Francisco Bezanilla, João L. Carvalho-de-Souza, Igor Vurgaftman, David R. Pepperberg, Eunkeu Oh, James B. Delehanty, Alan L. Huston, Okhil K. Nag
Publikováno v:
ACS Chemical Neuroscience. 10:1478-1487
Gold nanoparticles (AuNPs) attached to the extracellular leaflet of the plasma membrane of neurons can enable the generation of action potentials (APs) in response to brief pulses of light. Recently described techniques to stably bind AuNP bioconjuga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab62797f4a9770d3d21ba7ab0bb0f2cf
https://doi.org/10.1021/acschemneuro.8b00486
https://doi.org/10.1021/acschemneuro.8b00486
Publikováno v:
Biophysical Journal
Millisecond pulses of laser light delivered to gold nanoparticles residing in close proximity to the surface membrane of neurons can induce membrane depolarization and initiate an action potential. An optocapacitance mechanism proposed as the basis o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61ed5b45fb92fe0d506c5865fd602086
https://doi.org/10.1016/j.bpj.2017.11.018
https://doi.org/10.1016/j.bpj.2017.11.018
Autor:
Robert F. Standaert, David R. Pepperberg, Jun Yan, Haohua Qian, An Xie, Laura J. Frishman, Deb Kumar Mojumder, Jing Wang
Publikováno v:
Experimental Eye Research. 139:48-63
All three classes of receptors for the inhibitory neurotransmitter GABA (GABAR) are expressed in the retina. This study investigated roles of GABAR, especially GABA C R (GABA(A)-ρ), in retinal signaling in vivo by studying effects on the mouse elect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::839fe1a5c675f724a54fdcec40614d6e
https://doi.org/10.1016/j.exer.2015.07.002
https://doi.org/10.1016/j.exer.2015.07.002
Autor:
Michael P. Fautsch, David W. Rodgers, Zahra Derafshi, John R. Hetling, Louis B. Hersh, Rajni Parthasarathy, K. Martin Chow, David R. Pepperberg
Publikováno v:
Experimental Eye Research. 138:134-144
Amyloid-beta (Aβ) is a group of aggregation-prone, 38- to 43-amino acid peptides generated in the eye and other organs. Numerous studies suggest that the excessive build-up of low-molecular-weight soluble oligomers of Aβ plays a role in the progres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21c37c9216aaf2fd59bc19f21025052f
https://doi.org/10.1016/j.exer.2015.06.027
https://doi.org/10.1016/j.exer.2015.06.027
Autor:
Eunkeu Oh, David R. Pepperberg, Igor Vurgaftman, Joao A. Carvalho-de-Souza, Okhil K. Nag, Francisco Bezanilla, Alan J. Huston, James B. Delehanty
Publikováno v:
Biophysical Journal. 116:276a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02a9bc60d8736537efd5894a1105f38d
https://doi.org/10.1016/j.bpj.2018.11.1493
https://doi.org/10.1016/j.bpj.2018.11.1493
Publikováno v:
Analytical Biochemistry. 432:49-57
This study reports the preparation and characterization of cysteine-terminated B-domain (Bd-cys) of Staphylococcus aureus protein A, in combination with immunoglobulin G (IgG) antibodies directed against the ρ1 and α1 subunits of GABA(A) receptors,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dca57f14581234a6598f327048796f73
https://doi.org/10.1016/j.ab.2012.08.031
https://doi.org/10.1016/j.ab.2012.08.031
Autor:
Brian M. Bennett, Jia Luo, Mary Jo LaDu, David R. Pepperberg, Manel Ben Aissa, Sue H. Lee, Gregory R. J. Thatcher, Ottavio Arancio
Publikováno v:
Alzheimer's & Dementia. 12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bbd858e2bfb000872e59af714f730d9
https://doi.org/10.1016/j.jalz.2016.06.782
https://doi.org/10.1016/j.jalz.2016.06.782
Autor:
David R. Pepperberg, Haohua Qian, Deborah M. Little, Hélène A. Gussin, Sandra J. Rosenthal, Ian D. Tomlinson, Niraj J. Muni
Publikováno v:
Bioconjugate Chemistry. 21:1455-1464
Highly fluorescent CdSe quantum dots (qdots) can serve as a platform for tethering multiple copies of a receptor-targeted ligand, affording study of how the level of multivalency affects receptor binding. We previously showed that qdots conjugated wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeedf69dd7ead861cc64d9ba38cbd818
https://doi.org/10.1021/bc100050s
https://doi.org/10.1021/bc100050s