Zobrazeno 1 - 3
of 3
pro vyhledávání: '"David R, Huron"'
Autor:
Jochen Buck, Kenneth C. Hess, Jeanne Farrell, David R Huron, Margarita Kamenetsky, Jonathan H. Zippin, Lonny R. Levin, Donald A. Fischman
Publikováno v:
The Journal of Cell Biology
Bicarbonate-responsive “soluble” adenylyl cyclase resides, in part, inside the mammalian cell nucleus where it stimulates the activity of nuclear protein kinase A to phosphorylate the cAMP response element binding protein (CREB). The existence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57a2ce2c05d290731f9b01b2d89068d1
https://doi.org/10.1083/jcb.200311119
https://doi.org/10.1083/jcb.200311119
Publikováno v:
British Journal of Pharmacology. 126:1253-1261
Ethanol inhibits inducible nitric oxide synthase (iNOS) expression in C6 glioma cells by an unknown mechanism. Because relatively high concentrations are needed for inhibition in drug-naive cells (IC50∼150 mM), suppression due to cytotoxicity is on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::428780630eac6540d8a404fa728b60bc
https://doi.org/10.1038/sj.bjp.0702417
https://doi.org/10.1038/sj.bjp.0702417
Autor:
David R, Huron, Mercedes E, Gorre, Alan J, Kraker, Charles L, Sawyers, Neal, Rosen, Mark M, Moasser
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 9(4)
Inhibition of the constitutively active Bcr-abl tyrosine kinase(TK) by STI571 has proven to be a highly effective treatment for chronic myelogenous leukemia (CML). However, STI571 is only transiently effective in blast crisis, and drug resistance eme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c789e3d4a690f614e8c64e3317f8c290
https://pubmed.ncbi.nlm.nih.gov/12684388
https://pubmed.ncbi.nlm.nih.gov/12684388