Zobrazeno 1 - 10
of 91
pro vyhledávání: '"David R, Goldsmith"'
Publikováno v:
Journal of Clinical and Translational Science, Vol 8, Pp 143-143 (2024)
OBJECTIVES/GOALS: Previous research has linked inflammation to changes in brain reward circuitry and subsequent negative symptoms in patients with schizophrenia. This project aims to understand brain-immune interactions using diffusion tensor imaging
Externí odkaz:
https://doaj.org/article/8a9b49f253fe4248a17dbda5c05c2994
Publikováno v:
npj Schizophrenia, Vol 7, Iss 1, Pp 1-3 (2021)
Abstract Finding biological predictors and novel mechanisms underlying negative symptoms of schizophrenia is of significant importance given the lack of effective treatments. Increasing data support a role for metabolic dysfunction and inflammation i
Externí odkaz:
https://doaj.org/article/2c039871bbb849329baef33f2d50e700
Publikováno v:
Frontiers in Integrative Neuroscience, Vol 15 (2022)
Delusions are marked, fixed beliefs that are incongruent with reality. Delusions, with comorbid hallucinations, are a hallmark of certain psychotic disorders (e.g., schizophrenia). Delusions can present transdiagnostically, in neurodegenerative (e.g.
Externí odkaz:
https://doaj.org/article/1df6006eed19431585d09f4a039d5542
Publikováno v:
Biological Psychiatry. 93:405-418
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62e60b48e1d09e3cb7fd33fe48f5a6d4
https://doi.org/10.1016/j.biopsych.2022.11.003
https://doi.org/10.1016/j.biopsych.2022.11.003
Autor:
Bradley D. Pearce, Nicholas Massa, David R. Goldsmith, Zeal H. Gandhi, Allison Hankus, Alaaeddin Alrohaibani, Neha Goel, Bruce Cuthbert, Molly Fargotstein, Dana Boyd Barr, Parinya Panuwet, Victoria M. Brown, Erica Duncan
Publikováno v:
Frontiers in Psychiatry, Vol 11 (2020)
Background: Chronic infection with Toxoplasma gondii (TOXO) results in microcysts in the brain that are controlled by inflammatory activation and subsequent changes in the kynurenine pathway. TOXO seropositivity is associated with a heightened risk o
Externí odkaz:
https://doaj.org/article/813f00106ac44f34b8c16518f99e1ed0
Publikováno v:
Frontiers in Psychiatry, Vol 11 (2020)
First episode psychosis (FEP), and subsequent diagnosis of schizophrenia or schizoaffective disorder, predominantly occurs during late adolescence, is accompanied by a significant decline in function and represents a traumatic experience for patients
Externí odkaz:
https://doaj.org/article/43fad811b77e4780857a590d07d9d39d
Publikováno v:
Frontiers in Psychiatry, Vol 11 (2020)
Negative symptoms of schizophrenia are debilitating and chronic in nature, are difficult to treat, and contribute to poor functional outcomes. Motivational deficits are a core negative symptom and may involve alterations in reward processing, which i
Externí odkaz:
https://doaj.org/article/162b00102c304104a793a8af52a3d393
Publikováno v:
Community Mental Health Journal. 59:641-653
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b630383783f363b4006555fdf617c81b
https://doi.org/10.1007/s10597-022-01045-2
https://doi.org/10.1007/s10597-022-01045-2
Autor:
Brian J. Miller, David R. Goldsmith
Publikováno v:
Biomarkers in Neuropsychiatry, Vol 1, Iss , Pp - (2019)
The longstanding investigation of immune system abnormalities, including inflammation, in schizophrenia has tremendous renewed interest as an area of research. Presently, the field has an unparalleled opportunity to investigate inflammation as a pote
Externí odkaz:
https://doaj.org/article/6603868aec00446596065dc9a45b25f1
Autor:
Jennifer C. Felger, Bobbi J. Woolwine, David R. Goldsmith, Ebrahim Haroon, Mandakh Bekhbat, Andrew H. Miller
Publikováno v:
Molecular Psychiatry. 26:7384-7392
Inflammation impacts basal ganglia motor circuitry in association with psychomotor retardation, a key symptom of major depression (MD). We previously reported associations between circulating protein inflammatory biomarkers and psychomotor slowing as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5322f936afb11dcce098c8587ff7f2a9
https://doi.org/10.1038/s41380-021-01258-z
https://doi.org/10.1038/s41380-021-01258-z