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pro vyhledávání: '"David Puibert"'
Autor:
Eva Thijssen, Jonas M. den Heijer, David Puibert, Emilie M.J. van Brummelen, Tatjana Naranda, Geert Jan Groeneveld
Publikováno v:
Parkinsonism & Related Disorders, 97, 84-90. ELSEVIER SCI LTD
Introduction: Apomorphine is used to treat OFF periods in Parkinson's disease (PD) patients. AZ-009 is a novel apomorphine formulation that delivers a thermally-generated aerosol to the deep lung via inhalation with a single breath.Methods: Part A wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbf91d3a50d3f79c4a0671fa5dc6c7c8
http://hdl.handle.net/1887/3479839
http://hdl.handle.net/1887/3479839
A Randomized Trial Assessing the Safety, Pharmacokinetics, and Efficacy During Morning Off of AZ-009
Autor:
Eva Thijssen, Jonas den Heijer, David Puibert, Laurence Moss, Mingzu Lei, David Hasegawa, Kyo Keum, Ken Mochel, Mohammed Ezzeldin Sharaf, Tom Alfredson, Wenxiang Zeng, Emilie van Brummelen, Tatjana Naranda, Geert Jan Groeneveld
Publikováno v:
Movement Disorders, 37(4), 790-798. WILEY
Background: Inhalation of apomorphine could be a faster-acting and more user-friendly alternative to subcutaneous injection for treating off periods in Parkinson's disease (PD). Objective: The aim of this study was to compare the safety and pharmacok
Autor:
Adrian Ghita, Simona Nicoleta Duna, Simona Rizea-Savu, David Puibert, Adelina Ciuciuleaca, Irene Manzanera
Publikováno v:
Journal of Bioequivalence & Bioavailability. 11
The bioavailability of an active substance might be altered when a solid oral dosage form (SODF) is crushed or disintegrated and mixed with fluids or food in order to assist swallowing. In consequence, the current European Medicines Agency (EMA) prac