Zobrazeno 1 - 10
of 72
pro vyhledávání: '"David Propper"'
Autor:
Corina E. Antal, Tae Gyu Oh, Stefan Aigner, En-Ching Luo, Brian A. Yee, Tania Campos, Hervé Tiriac, Katherine L. Rothamel, Zhang Cheng, Henry Jiao, Allen Wang, Nasun Hah, Elizabeth Lenkiewicz, Jan C. Lumibao, Morgan L. Truitt, Gabriela Estepa, Ester Banayo, Senada Bashi, Edgar Esparza, Ruben M. Munoz, Jolene K. Diedrich, Nicole M. Sodir, Jasmine R. Mueller, Cory R. Fraser, Erkut Borazanci, David Propper, Daniel D. Von Hoff, Christopher Liddle, Ruth T. Yu, Annette R. Atkins, Haiyong Han, Andrew M. Lowy, Michael T. Barrett, Dannielle D. Engle, Gerard I. Evan, Gene W. Yeo, Michael Downes, Ronald M. Evans
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy in need of new therapeutic options. Using unbiased analyses of super-enhancers (SEs) as sentinels of core genes involved in cell-specific function, here we uncover a druggable SE
Externí odkaz:
https://doaj.org/article/57cc744cc0404cd39ed1bebee4e6eee7
Autor:
Mette Ø. Agerbæk, Sara R. Bang-Christensen, Ming-Hsin Yang, Thomas M. Clausen, Marina A. Pereira, Shreya Sharma, Sisse B. Ditlev, Morten A. Nielsen, Swati Choudhary, Tobias Gustavsson, Poul H. Sorensen, Tim Meyer, David Propper, Jonathan Shamash, Thor G. Theander, Alexandra Aicher, Mads Daugaard, Christopher Heeschen, Ali Salanti
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-4 (2022)
Externí odkaz:
https://doaj.org/article/f6392ecee1604c1c8634dfb49b15aea6
Autor:
Timothy Iveson, Kathleen A Boyd, Rachel S Kerr, Jose Robles-Zurita, Mark P Saunders, Andrew H Briggs, Jim Cassidy, Niels Henrik Hollander, Josep Tabernero, Andrew Haydon, Bengt Glimelius, Andrea Harkin, Karen Allan, John McQueen, Sarah Pearson, Ashita Waterston, Louise Medley, Charles Wilson, Richard Ellis, Sharadah Essapen, Amandeep S Dhadda, Mark Harrison, Stephen Falk, Sherif Raouf, Charlotte Rees, Rene K Olesen, David Propper, John Bridgewater, Ashraf Azzabi, David Farrugia, Andrew Webb, David Cunningham, Tamas Hickish, Andrew Weaver, Simon Gollins, Harpreet Wasan, James Paul
Publikováno v:
Health Technology Assessment, Vol 23, Iss 64 (2019)
Background: Oxaliplatin and fluoropyrimidine chemotherapy administered over 6 months is the standard adjuvant regimen for patients with high-risk stage II or III colorectal cancer. However, the regimen is associated with cumulative toxicity, characte
Externí odkaz:
https://doaj.org/article/4215111445164519a465163178fd46e0
Autor:
Mette Ø. Agerbæk, Sara R. Bang-Christensen, Ming-Hsin Yang, Thomas M. Clausen, Marina A. Pereira, Shreya Sharma, Sisse B. Ditlev, Morten A. Nielsen, Swati Choudhary, Tobias Gustavsson, Poul H. Sorensen, Tim Meyer, David Propper, Jonathan Shamash, Thor G. Theander, Alexandra Aicher, Mads Daugaard, Christopher Heeschen, Ali Salanti
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Isolation of circulating tumor cells (CTCs) allows for non-invasive disease monitoring and characterization. Here the authors describe an alternative CTC isolation method based on the ability of the malaria rVAR2 protein to specifically bind oncofeta
Externí odkaz:
https://doaj.org/article/d35e924f66fe4e69b0fc7725f51ae674
Autor:
Irene Olivera, Rebeca Sanz-Pamplona, Elixabet Bolaños, Inmaculada Rodriguez, Iñaki Etxeberria, Assunta Cirella, Josune Egea, Saray Garasa, Itziar Migueliz, Iñaki Eguren-Santamaria, Miguel F. Sanmamed, Javier Glez-Vaz, Arantza Azpilikueta, Maite Alvarez, María C. Ochoa, Beatrice Malacrida, David Propper, Carlos E. de Andrea, Pedro Berraondo, Frances R. Balkwill, Álvaro Teijeira, Ignacio Melero
Publikováno v:
Cancer Discovery. 12:2140-2157
Interleukin-8 (CXCL8) produced in the tumor microenvironment correlates with poor response to checkpoint inhibitors and is known to chemoattract and activate immunosuppressive myeloid leukocytes. In human cancer, IL8 mRNA levels correlate with IL1B a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d25b55e5706c4705e0a55ff724dfb496
https://doi.org/10.1158/2159-8290.cd-21-1115
https://doi.org/10.1158/2159-8290.cd-21-1115
Autor:
Marie‐Rose Dwek, Stanton P. Newman, Stefano Brini, Pru Holder, Michael Machesney, David Propper, Lorna R. Rixon, Shashivadan P. Hirani, Catherine S. Hurt
Publikováno v:
Psycho-Oncology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b0f79922c41f49ce0b82e29490d5c3c
https://doi.org/10.1002/pon.6147
https://doi.org/10.1002/pon.6147
Autor:
Ignacio Melero, Álvaro Teijeira, Frances R. Balkwill, Pedro Berraondo, Carlos E. de Andrea, David Propper, Beatrice Malacrida, María C. Ochoa, Maite Alvarez, Arantza Azpilikueta, Javier Glez-Vaz, Miguel F. Sanmamed, Iñaki Eguren-Santamaria, Itziar Migueliz, Saray Garasa, Josune Egea, Assunta Cirella, Iñaki Etxeberria, Inmaculada Rodriguez, Elixabet Bolaños, Rebeca Sanz-Pamplona, Irene Olivera
Supplementary Figure from A Therapeutically Actionable Protumoral Axis of Cytokines Involving IL-8, TNFα, and IL-1β
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f32d8b6c5cd605ff447850ccc7e59f0
https://doi.org/10.1158/2159-8290.22541500.v1
https://doi.org/10.1158/2159-8290.22541500.v1
Autor:
Ignacio Melero, Álvaro Teijeira, Frances R. Balkwill, Pedro Berraondo, Carlos E. de Andrea, David Propper, Beatrice Malacrida, María C. Ochoa, Maite Alvarez, Arantza Azpilikueta, Javier Glez-Vaz, Miguel F. Sanmamed, Iñaki Eguren-Santamaria, Itziar Migueliz, Saray Garasa, Josune Egea, Assunta Cirella, Iñaki Etxeberria, Inmaculada Rodriguez, Elixabet Bolaños, Rebeca Sanz-Pamplona, Irene Olivera
Interleukin-8 (CXCL8) produced in the tumor microenvironment correlates with poor response to checkpoint inhibitors and is known to chemoattract and activate immunosuppressive myeloid leukocytes. In human cancer, IL8 mRNA levels correlate with IL1B a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::968f3422d851bd514a8234d09869527b
https://doi.org/10.1158/2159-8290.c.6549661
https://doi.org/10.1158/2159-8290.c.6549661
Autor:
David Propper, Frances Balkwill
Publikováno v:
Nature Reviews Clinical Oncology. 19:237-253
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eeecf45c1bf4bed2fd97700eb9b4b9e8
https://doi.org/10.1038/s41571-021-00588-9
https://doi.org/10.1038/s41571-021-00588-9
Autor:
David Propper, Erkut Borazanci, Haiyong Han, Daniel Von Hoff, Tannishtha Reya, Jonathan Ghergurovich, Irina Pshenichnaya, Corina Antal, Rachel Condjella, Shreya Sharma, Peter O'Dwyer, Trevor Littlewood, Ashok Saluja, Mohana Velagapudi, Lifeng Yang, Michael Downes, Ronald Evans, Gerard Evan, Hitendra Patel
Publikováno v:
Pancreatology. 23:e5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e67c8078637edd2be3c053cc13d87c1
https://doi.org/10.1016/j.pan.2023.04.020
https://doi.org/10.1016/j.pan.2023.04.020