Zobrazeno 1 - 8
of 8
pro vyhledávání: '"David Prihoda"'
Autor:
Andrew B. Waight, David Prihoda, Rojan Shrestha, Kevin Metcalf, Marc Bailly, Marco Ancona, Talal Widatalla, Zachary Rollins, Alan C Cheng, Danny A. Bitton, Laurence Fayadat-Dilman
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTIdentification of favorable biophysical properties for protein therapeutics as part of developability assessment is a crucial part of the preclinical development process. Successful prediction of such properties and bioassay results from calc
Externí odkaz:
https://doaj.org/article/b097c809663e4798a43b8ba6b107fe06
Autor:
David Prihoda, Jad Maamary, Andrew Waight, Veronica Juan, Laurence Fayadat-Dilman, Daniel Svozil, Danny A. Bitton
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
Despite recent advances in transgenic animal models and display technologies, humanization of mouse sequences remains one of the main routes for therapeutic antibody development. Traditionally, humanization is manual, laborious, and requires expert k
Externí odkaz:
https://doaj.org/article/1cfab3de8e254294ae2cd13c6a106121
BackgroundDespite the advent of Next Generation Sequencing technology and its widespread applications, Sanger sequencing remains instrumental for molecular biology subcloning work in biological and medical research and indispensable for drug discover
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d54bca8eec9379997f0ac2ae723f522
https://doi.org/10.1101/2022.07.28.501824
https://doi.org/10.1101/2022.07.28.501824
Autor:
David Prihoda, Danny A. Bitton, Rastislav Svarba, Jakub Arnold, Alejandro Vazquez-Otero, Jakub Kotowski, Grant S. Murphy, Ondrej Tupa, Josef Navratil, Ondrej Klempir, Russell Jay, Sebastian Wiewiora, Anna Gromek, Matej Marcisin, Kamila Clarova, Martin Spale, Lukas Holy, Kaori Hiraga, David Dzamba, Gergely Temesi, Nikita Vostrosablin, Marcin W Walas, Petr Mejzlik, Nicholas M. Marshall
Publikováno v:
ACS Synthetic Biology. 10:357-370
Protein engineering is the discipline of developing useful proteins for applications in research, therapeutic and industrial processes by modification of naturally occurring proteins or by invention of de novo proteins. Modern protein engineering rel
Autor:
Geoffrey D. Hannigan, Ondrej Klempir, David Prihoda, Daria J. Hazuda, Danny A. Bitton, Julia M. Maritz, Christopher H. Woelk, David Dzamba
Publikováno v:
Natural Product Reports. 38:1100-1108
Covering: up to the end of 2020. The machine learning field can be defined as the study and application of algorithms that perform classification and prediction tasks through pattern recognition instead of explicitly defined rules. Among other areas,
Autor:
Jad Maamary, Andrew Waight, Danny A. Bitton, David Prihoda, Daniel Svozil, Laurence Fayadat-Dilman, Veronica Juan
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
Despite recent advances in transgenic animal models and display technologies, humanization of mouse sequences remains the primary route for therapeutic antibody development. Traditionally, humanization is manual, laborious, and requires expert knowle
Autor:
Geoffrey D. Hannigan, Jindrich Durcak, Christopher H. Woelk, Daria J. Hazuda, Michael Wurst, Ondrej Klempir, Dan Chang, David Prihoda, Rurun Wang, Jindrich Soukup, Jakub Kotowski, Andrej Palička, Danny A. Bitton, Lena Rampula, Grazia Piizzi
Natural products represent a rich reservoir of small molecule drug candidates utilized as antimicrobial drugs, anticancer therapies, and immunomodulatory agents. These molecules are microbial secondary metabolites synthesized by co-localized genes te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1582d82622f26d46501aee71c18d602
https://doi.org/10.1101/500694
https://doi.org/10.1101/500694
Autor:
Danny A. Bitton, Michael Wurst, Grazia Piizzi, Dan Chang, Jakub Kotowski, Lena Rampula, Jindrich Soukup, Andrej Palička, Christopher H. Woelk, David Prihoda, Geoffrey D. Hannigan, Jindrich Durcak, Rurun Wang, Daria J. Hazuda, Gergely Temesi, Ondrej Klempir
Publikováno v:
Nucleic Acids Research
Natural products represent a rich reservoir of small molecule drug candidates utilized as antimicrobial drugs, anticancer therapies, and immunomodulatory agents. These molecules are microbial secondary metabolites synthesized by co-localized genes te