Zobrazeno 1 - 3
of 3
pro vyhledávání: '"David Presky"'
Autor:
Michael Dziegelewski, David Presky, Susan van Tongeren, Steve Fogal, Rachel Kroe-Barrett, Helen Wu, Sanjaya Singh, Tobias Litzenberger, Scott Brodeur, Gale Hansen, Christine Grimaldi, Eliud Sepuldeva, Zhong-Fu Huang, Dongmei Liu, Hua Li, Kerry-Leigh Ralph, Lee Frego, Jennifer Ahlberg
Publikováno v:
International Journal of Pharmaceutics. 609:121162
Antibodies targeting the CD40-CD40L pathway have great potential for treating autoimmune diseases like rheumatoid arthritis, systemic lupus erythematosus (SLE), lupus nephritis (LN), and inflammatory bowel diseases (IBD). However, in addition to the
Autor:
David Presky, Qi Pan, Amy Marie Nicoletti, Ashraf Khalil, Scott M DeWire, Kerry L. M. Ralph, Sathyadevi Venkataramani, Julie Ritchie, Brodeur Scott, Cynthia Hess Kenny
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 359:37-44
Therapeutic agents antagonizing B-cell-activating factor/B-lymphocyte stimulator (BAFF/BLyS) are currently in clinical development for autoimmune diseases; belimumab is the first Food and Drug Administration-approved drug in more than 50 years for th
Autor:
David Presky, Ernest L. Raymond, Catron Katrina Mary, Jeffrey H Hanke, Keith Canada, Lee Frego, Laura Amodeo, Jennifer Ahlberg, Eliud Sepulveda, Rachel Kroe-Barrett, Xiang Zhu, Helen Wu, Yaqin He, Sanjaya Singh
Publikováno v:
mAbs
Herein, we describe the generation and characterization of BI 655066, a novel, highly potent neutralizing anti-interleukin-23 (IL23) monoclonal antibody in clinical development for autoimmune conditions, including psoriasis and Crohn's disease. IL23