Zobrazeno 1 - 10
of 173
pro vyhledávání: '"David Prangishvili"'
Autor:
Simona Pilotto, Thomas Fouqueau, Natalya Lukoyanova, Carol Sheppard, Soizick Lucas-Staat, Luis Miguel Díaz-Santín, Dorota Matelska, David Prangishvili, Alan C. M. Cheung, Finn Werner
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Understanding the structural basis for the inhibition of archaeal eukaryotic-like RNA polymerases (RNAPs) during virus infection is of interest for drug design. Here, the authors present the cryo-EM structures of apo Sulfolobus acidocaldarius RNAP an
Externí odkaz:
https://doaj.org/article/3d39de805d944392bdd55093bfcb0759
Autor:
Fengbin Wang, Diana P. Baquero, Zhangli Su, Leticia C. Beltran, David Prangishvili, Mart Krupovic, Edward H. Egelman
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Archaeal type IV pili (T4P) mediate adhesion to surfaces and are receptors for hyperthermophilic archaeal viruses. Here, the authors present the cryo-EM structures of two archaeal T4P from Pyrobaculum arsenaticum and Saccharolobus solfataricus and di
Externí odkaz:
https://doaj.org/article/31978e1666b74a5a97a9513c11bde8c2
Autor:
Ying Liu, Tatiana A Demina, Simon Roux, Pakorn Aiewsakun, Darius Kazlauskas, Peter Simmonds, David Prangishvili, Hanna M Oksanen, Mart Krupovic
Publikováno v:
PLoS Biology, Vol 19, Iss 11, p e3001442 (2021)
The archaeal tailed viruses (arTV), evolutionarily related to tailed double-stranded DNA (dsDNA) bacteriophages of the class Caudoviricetes, represent the most common isolates infecting halophilic archaea. Only a handful of these viruses have been ge
Externí odkaz:
https://doaj.org/article/23bdb8cb705e4df2a50db5a7e1f0f2c5
Autor:
Sofia Medvedeva, Ying Liu, Eugene V. Koonin, Konstantin Severinov, David Prangishvili, Mart Krupovic
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Here, the authors investigate the diversity and dynamics of the CRISPRome in the hyperthermophilic archaea of the order Sulfolobales, and find the most abundant spacers to come from mini-CRISPR arrays of archaeal viruses, which might represent a stra
Externí odkaz:
https://doaj.org/article/0f7787401265461ca35e0bb2238ed9cf
Autor:
Ying Liu, Tomasz Osinski, Fengbin Wang, Mart Krupovic, Stefan Schouten, Peter Kasson, David Prangishvili, Edward H. Egelman
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Only a few archaeal filamentous viruses have been structurally characterized. Here the authors describe the membrane-enveloped Sulfolobus filamentous virus 1 that infects Sulfolobus shibatae and present its 3.7 Å resolution cryo-EM structure, which
Externí odkaz:
https://doaj.org/article/3f7402139f604503a99b80ab686da655
Autor:
Denis Ptchelkine, Ashley Gillum, Tomohiro Mochizuki, Soizick Lucas-Staat, Ying Liu, Mart Krupovic, Simon E. V. Phillips, David Prangishvili, Juha T. Huiskonen
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-6 (2017)
The rod-shaped virus APBV1 is among the most thermostable viruses known. Here, Ptchelkine et al. determine its structure at near-atomic resolution, show that the DNA is packed as left-handed superhelix and identify extended hydrophobic interfaces tha
Externí odkaz:
https://doaj.org/article/2658d6e813804f9a970e1412f0a78165
Autor:
Ekaterine Jaiani, Ia Kusradze, Tamar Kokashvili, Natia Geliashvili, Nino Janelidze, Adam Kotorashvili, Nato Kotaria, Archil Guchmanidze, Marina Tediashvili, David Prangishvili
Publikováno v:
Marine Drugs, Vol 18, Iss 11, p 558 (2020)
Viruses have the greatest abundance and highest genetic diversity in marine ecosystems. The interactions between viruses and their hosts is one of the hot spots of marine ecology. Besides their important role in various ecosystems, viruses, especiall
Externí odkaz:
https://doaj.org/article/833807dbb319482b8825d4fd6aa6a3b6
Autor:
Peter Kasson, Frank DiMaio, Xiong Yu, Soizick Lucas-Staat, Mart Krupovic, Stefan Schouten, David Prangishvili, Edward H Egelman
Publikováno v:
eLife, Vol 6 (2017)
Biological membranes create compartments, and are usually formed by lipid bilayers. However, in hyperthermophilic archaea that live optimally at temperatures above 80°C the membranes are monolayers which resemble fused bilayers. Many double-stranded
Externí odkaz:
https://doaj.org/article/180a770761fb4ee38f8c359bc9b3cc25
Autor:
Emmanuelle R. J. Quemin, Petr Chlanda, Martin Sachse, Patrick Forterre, David Prangishvili, Mart Krupovic
Publikováno v:
mBio, Vol 7, Iss 5 (2016)
ABSTRACT Similar to many eukaryotic viruses (and unlike bacteriophages), viruses infecting archaea are often encased in lipid-containing envelopes. However, the mechanisms of their morphogenesis and egress remain unexplored. Here, we used dual-axis e
Externí odkaz:
https://doaj.org/article/5b221680de4c410a91a27fe7e1dd820e
Autor:
Eveline Peeters, Maarten Boon, Clare Rollie, Ronnie G. Willaert, Marleen Voet, Malcolm F. White, David Prangishvili, Rob Lavigne, Tessa E.F. Quax
Publikováno v:
Viruses, Vol 9, Iss 7, p 190 (2017)
Whereas the infection cycles of many bacterial and eukaryotic viruses have been characterized in detail, those of archaeal viruses remain largely unexplored. Recently, studies on a few model archaeal viruses such as SIRV2 (Sulfolobus islandicus rod-s
Externí odkaz:
https://doaj.org/article/30bfff90499e430da89f2fd09304e6fd