Zobrazeno 1 - 10
of 83
pro vyhledávání: '"David Potěšil"'
Autor:
Anna Vyhlídalová Kotrbová, Kristína Gömöryová, Antónia Mikulová, Hana Plešingerová, Stanislava Sladeček, Marek Kravec, Šárka Hrachovinová, David Potěšil, Garett Dunsmore, Camille Blériot, Mathilde Bied, Jan Kotouček, Markéta Bednaříková, Jitka Hausnerová, Luboš Minář, Igor Crha, Michal Felsinger, Zbyněk Zdráhal, Florent Ginhoux, Vít Weinberger, Vitězslav Bryja, Vendula Pospíchalová
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 3, Pp n/a-n/a (2024)
Abstract High‐grade serous carcinoma of the ovary, fallopian tube and peritoneum (HGSC), the most common type of ovarian cancer, ranks among the deadliest malignancies. Many HGSC patients have excess fluid in the peritoneum called ascites. Ascites
Externí odkaz:
https://doaj.org/article/dc1667b33f2d4fcab8e36f032b4b3b53
Autor:
Petra Martinková, Hana Konečná, Petr Gintar, Karolína Kryštofová, David Potěšil, Martin Trtílek, Zbyněk Zdráhal
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17347 (2023)
The success of bottom-up proteomic analysis frequently depends on the efficient removal of contaminants from protein or peptide samples before LC-MS/MS. For a peptide clean-up workflow, single-pot solid-phase-enhanced peptide sample preparation on ca
Externí odkaz:
https://doaj.org/article/f719cb1910f9466c9e07b340bf6e6484
Autor:
Pablo Bora, Lenka Gahurova, Tomáš Mašek, Andrea Hauserova, David Potěšil, Denisa Jansova, Andrej Susor, Zbyněk Zdráhal, Anna Ajduk, Martin Pospíšek, Alexander W. Bruce
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-19 (2021)
Bora et al. show that an early blastocyst window of p38-MAPK activity regulates ribosome-related gene expression, rRNA precursor processing, polysome formation, and protein translation. This study suggests a distinct role of p38-MAPKs for providing a
Externí odkaz:
https://doaj.org/article/2d718886001a4b338d26b0dc2ade0e25
Autor:
Kateřina Hanáková, Ondřej Bernatík, Marek Kravec, Miroslav Micka, Jitender Kumar, Jakub Harnoš, Petra Ovesná, Petra Paclíková, Matěj Rádsetoulal, David Potěšil, Konstantinos Tripsianes, Lukáš Čajánek, Zbyněk Zdráhal, Vítězslav Bryja
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-21 (2019)
Abstract Background Dishevelled (DVL) is an essential component of the Wnt signaling cascades. Function of DVL is controlled by phosphorylation but the molecular details are missing. DVL3 contains 131 serines and threonines whose phosphorylation gene
Externí odkaz:
https://doaj.org/article/59bcf25501ed4898813e2a7a806d2bac
Autor:
Tomasz Radaszkiewicz, Michaela Nosková, Kristína Gömöryová, Olga Vondálová Blanářová, Katarzyna Anna Radaszkiewicz, Markéta Picková, Ráchel Víchová, Tomáš Gybeľ, Karol Kaiser, Lucia Demková, Lucia Kučerová, Tomáš Bárta, David Potěšil, Zbyněk Zdráhal, Karel Souček, Vítězslav Bryja
Publikováno v:
eLife, Vol 10 (2021)
RNF43 is an E3 ubiquitin ligase and known negative regulator of WNT/β-catenin signaling. We demonstrate that RNF43 is also a regulator of noncanonical WNT5A-induced signaling in human cells. Analysis of the RNF43 interactome using BioID and immunopr
Externí odkaz:
https://doaj.org/article/429690658a42429e81ef4cee4109bc0b
Autor:
Pablo Bora, Lenka Gahurova, Andrea Hauserova, Martina Stiborova, Rebecca Collier, David Potěšil, Zbyněk Zdráhal, Alexander W. Bruce
Publikováno v:
Open Biology, Vol 11, Iss 7 (2021)
Successful navigation of the mouse preimplantation stages of development, during which three distinct blastocyst lineages are derived, represents a prerequisite for continued development. We previously identified a role for p38-mitogen-activated kina
Externí odkaz:
https://doaj.org/article/8f8d9742250e4edf97faf2b4b64916ec
Autor:
Karol Kaiser, Daniel Gyllborg, Jan Procházka, Alena Salašová, Petra Kompaníková, Francisco Lamus Molina, Rocio Laguna-Goya, Tomasz Radaszkiewicz, Jakub Harnoš, Michaela Procházková, David Potěšil, Roger A. Barker, Ángel Gato Casado, Zbyněk Zdráhal, Radislav Sedláček, Ernest Arenas, J. Carlos Villaescusa, Vítězslav Bryja
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
WNTs can signal over long distances but how this arises in the brain is unclear. Here, the authors show that WNT5A is secreted from the choroid plexus of the developing hindbrain (but not the telencephalon) and transported in the CSF with lipoprotein
Externí odkaz:
https://doaj.org/article/b5243ecd5bb74a85a22885abf4c818ed
Publikováno v:
Frontiers in Plant Science, Vol 12 (2021)
Quantitative protein extraction from biological samples, as well as contaminants removal before LC-MS/MS, is fundamental for the successful bottom-up proteomic analysis. Four sample preparation methods, including the filter-aided sample preparation (
Externí odkaz:
https://doaj.org/article/93236b1d89bb486a9aeb9fd4ef89f52f
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0231681 (2020)
Eudiplozoon nipponicum (Goto, 1891) is a hematophagous monogenean ectoparasite which inhabits the gills of the common carp (Cyprinus carpio). Heavy infestation can lead to anemia and in conjunction with secondary bacterial infections cause poor healt
Externí odkaz:
https://doaj.org/article/b9830f7f66f64f2eaa0fcbeda44d73b6
Publikováno v:
Molecular Neurodegeneration, Vol 12, Iss 1, Pp 1-19 (2017)
Abstract Background Autosomal-dominant mutations in the Park8 gene encoding Leucine-rich repeat kinase 2 (LRRK2) have been identified to cause up to 40% of the genetic forms of Parkinson’s disease. However, the function and molecular pathways regul
Externí odkaz:
https://doaj.org/article/7f8485c339104af4b90fee076b85caa8