nanos-Driven expression of piggyBac transposase induces mobilization of a synthetic autonomous transposon in the malaria vector mosquito, Anopheles stephensi

Autor: Vanessa M. Macias, Celine Hien Phong, Karen Chu, Osvaldo Marinotti, Anthony A. James, Alyssa J. Jimenez, David Pledger, Bianca Burini-Kojin, Aniko Fazekas, Nijole Jasinskiene, Kelcie Martin

Publikováno v: Insect biochemistry and molecular biology
Macias, VM; Jimenez, AJ; Burini-Kojin, B; Pledger, D; Jasinskiene, N; Phong, CH; et al.(2017). nanos-Driven expression of piggyBac transposase induces mobilization of a synthetic autonomous transposon in the malaria vector mosquito, Anopheles stephensi. INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY, 87, 81-89. doi: 10.1016/j.ibmb.2017.06.014. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/4987z1w0

Transposons are a class of selfish DNA elements that can mobilize within a genome. If mobilization is accompanied by an increase in copy number (replicative transposition), the transposon may sweep through a population until it is fixed in all of its

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https://doi.org/10.1016/j.ibmb.2017.06.014

Maternal germline-specific genes in the Asian malaria mosquito Anopheles stephensi: characterization and application for disease control

Autor: Yumin Qi, Zhijian Tu, David Pledger, James K. Biedler, Vanessa M. Macias, Anthony A. James

Publikováno v: G3 (Bethesda, Md.), vol 5, iss 2
G3: Genes|Genomes|Genetics
Biedler, JK; Qi, Y; Pledger, D; James, AA; & Tu, Z. (2015). Maternal germline-specific genes in the Asian malaria mosquito Anopheles stephensi: Characterization and application for disease control. G3: Genes, Genomes, Genetics, 5(2), 157-166. doi: 10.1534/g3.114.015578. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/3b97d7tk

Anopheles stephensi is a principal vector of urban malaria on the Indian subcontinent and an emerging model for molecular and genetic studies of mosquito biology. To enhance our understanding of female mosquito reproduction, and to develop new tools

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https://escholarship.org/uc/item/3b97d7tk