Zobrazeno 1 - 10
of 24
pro vyhledávání: '"David Pla‐Martín"'
Autor:
Ayesha Sen, Sebastian Kallabis, Felix Gaedke, Christian Jüngst, Julia Boix, Julian Nüchel, Kanjanamas Maliphol, Julia Hofmann, Astrid C. Schauss, Marcus Krüger, Rudolf J. Wiesner, David Pla-Martín
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Mitochondrial quality control mechanisms prevent damage accumulation, including in mitochondrial DNA (mtDNA). Here, Sen et al. show that altered mtDNA elicits local rearrangements in mitochondrial membrane potential and cristae structure, with mtDNA
Externí odkaz:
https://doaj.org/article/09a00f8e2ea74f67a21ec565d68bba22
Autor:
Sammy Kimoloi, Ayesha Sen, Stefan Guenther, Thomas Braun, Tobias Brügmann, Philipp Sasse, Rudolf J. Wiesner, David Pla‐Martín, Olivier R. Baris
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 4, Pp 2132-2145 (2022)
Abstract Background Mitochondrial dysfunction caused by mitochondrial (mtDNA) deletions have been associated with skeletal muscle atrophy and myofibre loss. However, whether such defects occurring in myofibres cause sarcopenia is unclear. Also, the c
Externí odkaz:
https://doaj.org/article/15e959a1114e4a8dadd0b7d4b985fc9e
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Mitochondrial dysfunction is a central feature of neurodegeneration within the central and peripheral nervous system, highlighting a strong dependence on proper mitochondrial function of neurons with especially high energy consumptions. The fitness o
Externí odkaz:
https://doaj.org/article/6b8cdf1d48a84950b8e1cf4fc48106bc
Autor:
David Pla-Martín, Carlos B. Rueda, Anna Estela, Maribel Sánchez-Piris, Paloma González-Sánchez, Javier Traba, Sergio de la Fuente, Luca Scorrano, Jaime Renau-Piqueras, Javier Alvarez, Jorgina Satrústegui, Francesc Palau
Publikováno v:
Neurobiology of Disease, Vol 55, Iss , Pp 140-151 (2013)
GDAP1 is an outer mitochondrial membrane protein that acts as a regulator of mitochondrial dynamics. Mutations of the GDAP1 gene cause Charcot–Marie–Tooth (CMT) neuropathy. We show that GDAP1 interacts with the vesicle-organelle trafficking prote
Externí odkaz:
https://doaj.org/article/1fe3da0bf8e947c8b7c4fab7164fe967
Publikováno v:
Methods in Molecular Biology ISBN: 9781071629215
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d41815cbda80cba2453994e5dbece1a
https://doi.org/10.1007/978-1-0716-2922-2_13
https://doi.org/10.1007/978-1-0716-2922-2_13
Publikováno v:
Autophagy. :1-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ed3ba1e661239df1efd7575371e73e3
https://doi.org/10.1080/15548627.2023.2170959
https://doi.org/10.1080/15548627.2023.2170959
Autor:
Markus Krüger, Julia Hofmann, Ayesha Sen, David Pla-Martín, Sebastian Kallabis, Kanjanamas Maliphol, Rudolf J. Wiesner, Julian Nüchel
Integrity of mitochondrial DNA (mtDNA), encoding several subunits of the respiratory chain, is essential to maintain mitochondrial fitness. Mitochondria, as a central hub for metabolism, are affected in a wide variety of human diseases but also durin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dddfec611b02416c50b143f706db37a
https://doi.org/10.1101/2021.08.06.455397
https://doi.org/10.1101/2021.08.06.455397
Autor:
Peter Zentis, David Pla-Martín, Rafael R. Oexner, Sammy Kimoloi, Astrid Schauss, Rudolf J. Wiesner, Martin H. J. Wiesen, Thomas Paß, Olivier R. Baris
Publikováno v:
Investigative Ophthalmology & Visual Science
Investigative Ophthalmology & Visual Science, Association for Research in Vision and Ophthalmology, 2020, 61 (12), pp.14. ⟨10.1167/iovs.61.12.14⟩
Investigative Ophthalmology & Visual Science, 2020, 61 (12), pp.14. ⟨10.1167/iovs.61.12.14⟩
Investigative Ophthalmology & Visual Science, Association for Research in Vision and Ophthalmology, 2020, 61 (12), pp.14. ⟨10.1167/iovs.61.12.14⟩
Investigative Ophthalmology & Visual Science, 2020, 61 (12), pp.14. ⟨10.1167/iovs.61.12.14⟩
International audience; Purpose: The purpose of this study was to gain insights on the pathogenesis of chronic progressive external ophthalmoplegia, thus we investigated the vulnerability of five extra ocular muscles (EOMs) fiber types to pathogenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf6d4edd741d894efdaccd75290c8537
https://hal.univ-angers.fr/hal-03003255/file/iovs-61-12-14.pdf
https://hal.univ-angers.fr/hal-03003255/file/iovs-61-12-14.pdf
Autor:
Salim Khiati, Marie-Charlotte Marx, Janica L Wiederstein, David Pla-Martín, Elena I. Rugarli, Désirée Schatton, Marcus Krüger
Publikováno v:
The EMBO Journal
Mitochondria house anabolic and catabolic processes that must be balanced and adjusted to meet cellular demands. The RNA‐binding protein CLUH (clustered mitochondria homolog) binds mRNAs of nuclear‐encoded mitochondrial proteins and is highly exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92eed4c9850f53d958e4a0387c0309dc
https://doi.org/10.15252/embj.2019102731
https://doi.org/10.15252/embj.2019102731
Autor:
Teresa Corona, Vangelis Kondylis, David Pla-Martín, Alberto Pessia, Ivan Nemazanyy, Peter Zentis, Astrid Schauss, Vidya Velagapudi, Elena I. Rugarli, Esther Barth, Henriette Hansen, Marie-Charlotte Marx, Désirée Schatton, Arnaud Mourier
Publikováno v:
The Journal of Cell Biology
CLUH binds mRNAs implicated in intermediate metabolism and oxidative phosphorylation, but the physiological and molecular significance of these interactions is unclear. Schatton et al. use new constitutive and liver-specific Cluh knockouts to define
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40a43b8fcf41b0f9ae081a8db60ff108
http://europepmc.org/articles/PMC5350512
http://europepmc.org/articles/PMC5350512