Zobrazeno 1 - 6
of 6
pro vyhledávání: '"David Pirovich"'
Autor:
Miles A. Miller, Bjorn Askevold, Hannes Mikula, Rainer H. Kohler, David Pirovich, Ralph Weissleder
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Palladium (Pd) is a well-known catalyst in organic chemistry but its use in nanomedicine is limited. Here, the authors design a Pd nanoparticle that triggers the activation of an antitumour prodrugin vivo, which shows efficacy and improves toxicity c
Externí odkaz:
https://doaj.org/article/b929185b46444f18bedc3e0efd655654
Publikováno v:
Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences, Vol 8 (2021)
Frontiers in Molecular Biosciences, Vol 8 (2021)
Fructose 1,6-bisphosphate aldolase is a ubiquitous cytosolic enzyme that catalyzes the fourth step of glycolysis. Aldolases are classified into three groups: Class-I, Class-IA, and Class-II; all classes share similar structural features but low amino
Autor:
Rainer H. Kohler, Hannes Mikula, Bjorn Askevold, Miles A. Miller, David Pirovich, Ralph Weissleder
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature Communications
Nature Communications
Palladium catalysts have been widely adopted for organic synthesis and diverse industrial applications given their efficacy and safety, yet their biological in vivo use has been limited to date. Here we show that nanoencapsulated palladium is an effe
Publikováno v:
BioEssays : news and reviews in molecular, cellular and developmental biology. 41(12)
Schistosomes are intravascular parasitic helminths (blood flukes) that infect more than 200 million people globally. Proteomic analysis of the tegument (skin) of these worms has revealed the surprising presence of glycolytic enzymes on the parasite's
Publikováno v:
Advanced Materials. 28:8675-8680
A novel metallo-bioadhesive to be used as tissue sealant in minimally invasive procedures is reported. Metal complexation can be used to render gelatin derivatives adhesive, which occurs in minutes, is efficient, and fully biodegradable within weeks.
Autor:
Ralph Weissleder, Randy J. Giedt, Jonathan C. T. Carlson, David Pirovich, Rainer H. Kohler, Labros G. Meimetis, Hannes Mikula
Publikováno v:
Chemical Communications. 52:9953-9956
Herein we describe the synthesis of several fluorescent analogues of the clinically approved microtubule destabilizing agent vinblastine. The evaluated probes are the most potent described and provides the first example of uptake, distribution and li