Zobrazeno 1 - 4
of 4
pro vyhledávání: '"David Pawlyk"'
Autor:
P. Gascon, Hans J. Hansen, Rae Vagg, Karen Burger, Jeffry A. Siegel, Sumathi Murthy, David M. Goldenberg, George Y. Wong, David Pawlyk, Lawrence C. Swayne, Robert M. Sharkey, Daniel O. Izon, Gary M. Levine
Publikováno v:
Cancer. 73:864-877
Background. Colon-specific antigen-p is a tumor-associated antigen present in approximately 60% of colorectal cancers. Preclinical studies have shown that the murine monoclonal antibody Mu-9 has excellent tumor-targeting abilities; therefore, clinica
Autor:
Rae Vagg, Hans J. Hansen, Carl M. Pinsky, David M. Goldenberg, Lawrence C. Swayne, Daniel O. Izon, Jeffry A. Siegel, Michael Vezza, Karen Burger, David Pawlyk, George Y. Wong, Sumathi Murthy, Robert M. Sharkey, Helene Pinsky, P. Gascon
Publikováno v:
Cancer. 71:2082-2096
Background. The authors previously reported that an anticarcinoembryonic antigen antibody against a carcinoembryonic antigen (CEA)-specific epitope is preferred for clinical investigations. They developed a second generation, CEA-specific murine mono
Autor:
Michele J. Losman, David Pawlyk, Ana M. Natale, Robert M. Sharkey, David M. Goldenberg, Marc Monestier, Otto C. Boerman
Publikováno v:
International journal of cancer. 51(2)
A syngeneic anti-idiotype monoclonal antibody (MAb) (CM-11) directed against an anti-carcinoembryonic antigen (CEA) murine MAb (NP-4) was evaluated as a second antibody (SA) to promote the rapid clearance of radiolabeled NP-4 from the blood. Initial
Autor:
Jo Ann Horowitz, Jeffry A. Siegel, Robert M. Sharkey, Robert E. Lee, David M. Goldenberg, David Pawlyk
Publikováno v:
International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology. 16:553-559
Myelosuppression has been identified as the dose-limiting toxicity in radioimmunotherapy studies. Accurate bone marrow dosimetry is, therefore, necessary to evaluate bone marrow toxicity which may result from systemic cancer treatment with radiolabel