Zobrazeno 1 - 10
of 58
pro vyhledávání: '"David P. de Bono"'
Publikováno v:
International Journal of Angiology. 7:18-21
Subacute thrombosis is a significant problem after stent insertion. Use of polymer-coated stents impregnated with drugs could reduce its incidence. We investigated the binding and elution kinetics and antithrombotic efficacy of three agents passively
Autor:
David P. de Bono, S Pringle, R S More, Malcolm J. Underwood, M. J. Brack, Anthony H. Gershlick
Publikováno v:
International Journal of Angiology. 4:83-87
We assessed whether chemical conjugation of a monoclonal antibody (M735) against platelet glycoprotein IIb/IIIa receptors to urokinase and to a monoclonal antibody which binds to damaged endothelium (P14G11) resulted in enhanced inhibition of platele
Publikováno v:
Experimental and Molecular Pathology. 70:146-153
We describe the expression of tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor (PAI-1) in saphenous vein culture. Smooth muscle cells (SMC) are quiescent in fresh tissue, whereas these cells acquire a proliferating phenoty
Autor:
David P. de Bono, Kai Hogrefe, Cathy M. Holt, J Armstrong, Anthony H. Gershlick, Michael Azrin, RK Aggarwal, Julia H. Baron, Michael D. Ezekowitz
Publikováno v:
Cardiovascular Research. 46:585-594
OBJECTIVE: Stent thrombosis and in-stent restenosis remain problematic in certain patient sub-groups. c7E3-Fab (ReoPro, abciximab) inhibits the platelet glycoprotein IIb/IIIa receptor as well as the smooth muscle cell alpha(v)beta3 receptor, and thus
Autor:
Penelope R. Sensky, Bruno Morgan, Asvina Jivan, Richard P. Keal, David P. de Bono, Graham R. Cherryman, N. Hudson, Nilesh J. Samani, J. Tranter
Publikováno v:
Radiology. 215:608-614
The authors developed and tested a dual stress magnetic resonance (MR) imaging protocol to evaluate myocardial perfusion, function, and hibernation. The technique was well tolerated, and high-quality images were achieved. The comprehensive informatio
Autor:
Julia H. Baron, David P. de Bono, Anthony H. Gershlick, Kai Hogrefe, Amanda J. Hussey, Roger Foo, Thomas W. Johnston, Ian Garner
Publikováno v:
Thrombosis and Haemostasis. 83:496-502
SummaryIn high-risk and complicated coronary intervention, the risk of acute closure is unpredictable. Thrombus and platelet deposition at the intervention site may also have further effects on subsequent restenosis. In vivo infusion of activated pro
Publikováno v:
International Journal of Angiology. 7:18-21
Publikováno v:
International Journal of Cardiology. 59:299-304
We sent a short postal questionnaire to 244 centres in England and Wales that admitted patients with cardiac conditions. In total, 199 (81%) of the centres claimed to provide a cardiac rehabilitation service. Of these, 25 were randomly selected as a
Publikováno v:
Clinical Science. 88:635-641
1. The aim of the present study was to investigate the effects of exercise and of sublingual glyceryl trinitrate on the pattern of blood flow, as studied by Doppler ultrasound, in internal mammary artery grafts performed to relieve severe stenosis of
Autor:
David P. de Bono
Publikováno v:
Baillière's Clinical Haematology. 8:403-412
Considering the enormous increase in the use of thrombolytic therapy over the last decade, many of the early concepts of thrombolytic therapy have proved to be remarkably robust. Early and sustained restoration of coronary patency remains the ultimat