Zobrazeno 1 - 10
of 20
pro vyhledávání: '"David P. Sherwood"'
Autor:
Katherine S. Morton, Jessica H. Hartman, Nathan Heffernan, Ian T. Ryde, Isabel W. Kenny-Ganzert, Lingfeng Meng, David R. Sherwood, Joel N. Meyer
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Background Diets high in saturated fat and sugar, termed “Western diets,” have been associated with several negative health outcomes, including increased risk for neurodegenerative disease. Parkinson’s disease (PD) is the second most p
Externí odkaz:
https://doaj.org/article/874606a651f54ef29a0f753f990c4cef
Publikováno v:
F1000Research, Vol 12 (2023)
Many developmental and physiological processes require cells to invade and migrate through extracellular matrix barriers. This specialized cellular behavior is also misregulated in many diseases, such as immune disorders and cancer. Cell invasive act
Externí odkaz:
https://doaj.org/article/69641ea8832a4c57939744c4f523230c
Autor:
Kieop Park, Ranjay Jayadev, Sara G Payne, Isabel W Kenny-Ganzert, Qiuyi Chi, Daniel S Costa, William Ramos-Lewis, Siddharthan B Thendral, David R Sherwood
Publikováno v:
eLife, Vol 12 (2023)
Separate tissues connect through adjoining basement membranes to carry out molecular barrier, exchange, and organ support functions. Cell adhesion at these connections must be robust and balanced to withstand independent tissue movement. Yet, how cel
Externí odkaz:
https://doaj.org/article/5e5db74a213b4415b17418b13699a45d
Autor:
Jayson J. Smith, Isabel W. Kenny, Carsten Wolff, Rachel Cray, Abhishek Kumar, David R. Sherwood, David Q. Matus
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Light sheet fluorescence microscopy (LSFM) has become a method of choice for live imaging because of its fast acquisition and reduced photobleaching and phototoxicity. Despite the strengths and growing availability of LSFM systems, no generalized LSF
Externí odkaz:
https://doaj.org/article/b28a4a92108c4e4ba0b2e0b53d54e780
Autor:
Aastha Garde, David R. Sherwood
Publikováno v:
STAR Protocols, Vol 3, Iss 2, Pp 101429- (2022)
Summary: Measuring ATP levels within the cytosol of living cells in animals is important to understand how cellular activities are energetically supported, but is challenging because of tissue complexity and ATP sensor limitations. In this protocol,
Externí odkaz:
https://doaj.org/article/ecdc485938764fc3902a2379c4c7b96d
Publikováno v:
eLife, Vol 9 (2020)
Stem cells reside in and rely upon their niche to maintain stemness but must balance self-renewal with the production of daughters that leave the niche to differentiate. We discovered a mechanism of stem cell niche exit in the canonical C. elegans di
Externí odkaz:
https://doaj.org/article/e3e20714a0fa4f76aea25ff45fde9087
Autor:
Jessica H. Hartman, Latasha L. Smith, Kacy L. Gordon, Ricardo Laranjeiro, Monica Driscoll, David R. Sherwood, Joel N. Meyer
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Abstract Exercise and caloric restriction improve health, including reducing risk of cardiovascular disease, neurological disease, and cancer. However, molecular mechanisms underlying these protections are poorly understood, partly due to the cost an
Externí odkaz:
https://doaj.org/article/72d3f1ab341c44bab535ac51b4bbcded
Autor:
John G. Carman, Mayelyn Mateo de Arias, Lei Gao, Xinghua Zhao, Becky M. Kowallis, David A. Sherwood, Manoj K. Srivastava, Krishna K. Dwivedi, Bo J. Price, Landon Watts, Michael D. Windham
Publikováno v:
Frontiers in Plant Science, Vol 10 (2019)
Apomixis (asexual seed formation) in angiosperms occurs either sporophytically, through adventitious embryony, or gametophytically, where an unreduced female gametophyte (embryo sac) forms and produces an unreduced egg that develops into an embryo pa
Externí odkaz:
https://doaj.org/article/b3dfe06b78b1409696724d3b8adc12b4
Publikováno v:
Journal of Microbiology & Biology Education, Vol 20, Iss 3 (2019)
Genome editing with CRISPR/Cas9 technology has advanced from the lab bench to clinical application with multiple trials underway. This article introduces a course-based undergraduate experience (CURE) combining CRISPR/Cas9 genome editing (using a mod
Externí odkaz:
https://doaj.org/article/557c2cec98fb4454a84c625d4850673c
Autor:
Mayelyn Mateo de Arias, Lei Gao, David A. Sherwood, Krishna K. Dwivedi, Bo J. Price, Michelle Jamison, Becky M. Kowallis, John G. Carman
Publikováno v:
Genes, Vol 11, Iss 12, p 1449 (2020)
In angiosperms, meiotic failure coupled with the formation of genetically unreduced gametophytes in ovules (apomeiosis) constitute major components of gametophytic apomixis. These aberrant developmental events are generally thought to be caused by mu
Externí odkaz:
https://doaj.org/article/a8ff4f432cf14d78ac264245d6a8a1c1