Zobrazeno 1 - 10
of 14
pro vyhledávání: '"David P. Regis"'
Autor:
David P. Regis, Charles R. Auker, Angela L. Senese, Richard T. Mahon, Francoise Arnaud, William A. Cronin
Publikováno v:
Blood Coagulation & Fibrinolysis. 27:702-710
Decompression from elevated ambient pressure is associated with platelet activation and decreased platelet counts. Standard treatment for decompression sickness (DCS) is hyperbaric oxygen therapy. Intravenous perfluorocarbon (PFC) emulsion is a nonre
Autor:
Richard T. Mahon, Shravalya Tirumala, Michael Bodo, David P. Regis, William A. Cronin, Charles R. Auker
Publikováno v:
Journal of Applied Physiology. 118:71-79
Intravenous perfluorocarbons (PFC) have reduced the effects of decompression sickness (DCS) and improved mortality rates in animal models. However, concerns for the physiological effects of DCS combined with PFC therapy have not been examined in a ba
Publikováno v:
Aviation, Space, and Environmental Medicine. 86:21-26
Introduction Perfluorocarbon (PFC) formulations can be a useful adjunct treatment for decompression sickness (DCS) when staged decompression procedures cannot be followed due to time constraints or lack of equipment. The benefit of PFC treatment is b
Publikováno v:
Aerospace medicine and human performance. 88(4)
INTRODUCTION Disabled submarine (DISSUB) survivors may face elevated CO2 levels and inert gas saturation, putting them at risk for CO2 toxicity and decompression sickness (DCS). Propranolol was shown to reduce CO2 production in an experimental DISSUB
Autor:
Richard T. Mahon, David P. Regis
Publikováno v:
Comprehensive Physiology
The ever-present desire of humankind to explore new limits introduced us to the syndrome of decompression sickness (DCS). This broad overview of DCS is aimed at its pathophysiology and basics of therapeutic strategies. After a brief explanation of de
Publikováno v:
Aviation, Space, and Environmental Medicine. 84:12-16
BACKGROUND Rescue from a disabled submarine may result in substantial risk for severe decompression sickness (DCS) among survivors. Oxygen prebreathe (OPB) before rapid decompression has been shown to significantly reduce risk or delay onset for seve
Publikováno v:
The FASEB Journal. 29
Purpose: Pulmonary oxygen toxicity (PO2T) is a concern for any patient or warfighter exposed to oxygen enriched atmospheres for an extended amount of time. While current practice is to limit increased oxygen exposure; there are clinical and operation
Publikováno v:
Annals of Allergy, Asthma & Immunology. 89:239-243
Introduction A 42-month-old female child presented with a 3-month history of left lower leg pain and 3 weeks of fevers to 38.9° C. The leg pain was a constant dull ache that had increased gradually. Her pain localized over the anterior left lower le
Autor:
Jennylynn Lejano, Carter L. Diggs, Joseph T. Bruder, Donald Brambilla, Sheetij Dutta, Victoria Steinbeiss, Glenna Banania, Jackie Williams, Christian F. Ockenhouse, Ilin Chuang, Kathryn Smith, Jittawadee Murphy, Denise L. Doolan, David P. Regis, Martha Sedegah, C. Richter King, Chloe Wood, Maria Belmonte, Thomas L. Richie, Renato Sayo, Keith Limbach, Fouzia Farooq, Cindy Tamminga, Charlotte Fedders, Noelle B. Patterson, Esteban Abot, Brent House, Judith E. Epstein, Harini Ganeshan, Jose Mendoza-Silveiras, Sharina Reyes, Lorraine Soisson, Daniel J. Carucci, Jack Komisar, Nancy O. Richie, Santina Maiolatesi, Michele D. Spring, Michael R. Hollingdale, Shannon McGrath, Nalini Manohar, Meng Shi, Gail Levine
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 10, p e25868 (2011)
PLoS ONE, Vol 6, Iss 10, p e25868 (2011)
Background A protective malaria vaccine will likely need to elicit both cell-mediated and antibody responses. As adenovirus vaccine vectors induce both these responses in humans, a Phase 1/2a clinical trial was conducted to evaluate the efficacy of a
Autor:
Brent House, Judith E. Epstein, Ilin Chuang, Martha Sedegah, Francis T. Williams, C. Richter King, Chloe Wood, Glenna Banania, Carole A. Long, David P. Regis, Keith Limbach, Jose Mendoza-Silveiras, Noelle B. Patterson, Thomas L. Richie, Sheetij Dutta, Maria Belmonte, Renato Sayo, Cindy Tamminga, Fouzia Farooq, Daniel J. Carucci, Carter L. Diggs, Esteban Abot, Harini Ganeshan, Lorraine Soisson, Meng Shi, Christian F. Ockenhouse, Denise L. Doolan, Joseph T. Bruder, Nalini Manohar, Shannon McGrath, Nancy O. Richie, Michele D. Spring, Michael R. Hollingdale, Jennylynn Lejano
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e24586 (2011)
PLoS ONE
PLoS ONE
Background Models of immunity to malaria indicate the importance of CD8+ T cell responses for targeting intrahepatic stages and antibodies for targeting sporozoite and blood stages. We designed a multistage adenovirus 5 (Ad5)-vectored Plasmodium falc