Zobrazeno 1 - 3
of 3
pro vyhledávání: '"David P. Purpi"'
Autor:
Keith T. Oldham, Alan N. Mayer, Jill S. Whitehouse, Kevin M. Riggle, David P. Purpi, David M. Gourlay, Kirkwood A. Pritchard
Publikováno v:
Journal of Surgical Research. 163:79-85
Background. Enterocytes produce intestinal alkaline phosphatase (iAP), which detoxifies lipopolysaccharide (LPS), a mediator in necrotizing enterocolitis (NEC) pathogenesis. We hypothesize that aberrant expression or function of iAP contributes to th
Combination chemotherapy forms the backbone of cancer treatment. There is a need for new drug combinations for the treatment of mantle cell lymphoma (MCL). Herein, we show that gallium maltolate, a novel gallium compound, synergizes with bortezomib,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3275d2cdee565436f7d4507762d3ede
https://europepmc.org/articles/PMC2875307/
https://europepmc.org/articles/PMC2875307/
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 322(3)
Clinical studies have shown gallium nitrate to have significant antitumor activity against non-Hodgkin's lymphoma and bladder cancer, thus indicating that gallium-based drugs have potential for further development as antineoplastic agents. In this st