Zobrazeno 1 - 10
of 120
pro vyhledávání: '"David P. Nickerson"'
Publikováno v:
Frontiers in Bioinformatics, Vol 3 (2023)
Maximising FAIRness of biosimulation models requires a comprehensive description of model entities such as reactions, variables, and components. The COmputational Modeling in BIology NEtwork (COMBINE) community encourages the use of Resource Descript
Externí odkaz:
https://doaj.org/article/d2447238311a4176833b135507e8b192
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
While ion channels and transporters involved in excitation-contraction coupling have been linked and constructed as comprehensive computational models, validation of whether each individual component of a model can be reused has not been previously a
Externí odkaz:
https://doaj.org/article/39155d543bff477dbd658a894c6093c5
Autor:
Yuda Munarko, Dewan M. Sarwar, Anand Rampadarath, Koray Atalag, John H. Gennari, Maxwell L. Neal, David P. Nickerson
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Semantic annotation is a crucial step to assure reusability and reproducibility of biosimulation models in biology and physiology. For this purpose, the COmputational Modeling in BIology NEtwork (COMBINE) community recommends the use of the Resource
Externí odkaz:
https://doaj.org/article/4989d70e88c544a7931c06baa0381d7e
Publikováno v:
PLoS ONE, Vol 17, Iss 6 (2022)
Hierarchical modelling is essential to achieving complex, large-scale models. However, not all modelling schemes support hierarchical composition, and correctly mapping points of connection between models requires comprehensive knowledge of each mode
Externí odkaz:
https://doaj.org/article/dd1f809b7f3d495db2bf127c6c0e7e35
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
It has been suggested that glucose absorption in the small intestine depends on both constitutively expressed SGLT1 and translocated GLUT2 in the brush border membrane, especially in the presence of high levels of luminal glucose. Here, we present a
Externí odkaz:
https://doaj.org/article/4da105d6e559422eb9156ca2be78d2c9
Autor:
Mahyar Osanlouy, Anita Bandrowski, Bernard de Bono, David Brooks, Antonino M. Cassarà, Richard Christie, Nazanin Ebrahimi, Tom Gillespie, Jeffrey S. Grethe, Leonardo A. Guercio, Maci Heal, Mabelle Lin, Niels Kuster, Maryann E. Martone, Esra Neufeld, David P. Nickerson, Elias G. Soltani, Susan Tappan, Joost B. Wagenaar, Katie Zhuang, Peter J. Hunter
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
The Data and Resource Center (DRC) of the NIH-funded SPARC program is developing databases, connectivity maps, and simulation tools for the mammalian autonomic nervous system. The experimental data and mathematical models supplied to the DRC by the S
Externí odkaz:
https://doaj.org/article/71c1ff663c464de39d8e73e6e0a64353
Autor:
Dewan M. Sarwar, Reza Kalbasi, John H. Gennari, Brian E. Carlson, Maxwell L. Neal, Bernard de Bono, Koray Atalag, Peter J. Hunter, David P. Nickerson
Publikováno v:
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-10 (2019)
Abstract Background Mathematics and Phy sics-based simulation models have the potential to help interpret and encapsulate biological phenomena in a computable and reproducible form. Similarly, comprehensive descriptions of such models help to ensure
Externí odkaz:
https://doaj.org/article/88988399891345fb876823d486557f18
Autor:
Megan E. Guidry, David P. Nickerson, Edmund J. Crampin, Martyn P. Nash, Denis S. Loiselle, Kenneth Tran
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
In experimental studies on cardiac tissue, the end-systolic force-length relation (ESFLR) has been shown to depend on the mode of contraction: isometric or isotonic. The isometric ESFLR is derived from isometric contractions spanning a range of muscl
Externí odkaz:
https://doaj.org/article/ccb06e400f27479dae91ce666348e9cd
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Absorption of glucose across the epithelial cells of the small intestine is a key process in human nutrition and initiates signaling cascades that regulate metabolic homeostasis. Validated and predictive mathematical models of glucose transport in in
Externí odkaz:
https://doaj.org/article/25afdaba26e14097906f5f56bd47c4e7
Autor:
Matthias König, Padraig Gleeson, Martin Golebiewski, Thomas E. Gorochowski, Michael Hucka, Sarah M. Keating, Chris J. Myers, David P. Nickerson, Björn Sommer, Dagmar Waltemath, Falk Schreiber
This special issue of the Journal of Integrative Bioinformatics contains updated specifications of COMBINE standards in systems and synthetic biology. The 2022 special issue presents three updates to the standards: CellML 2.0.1, SBML Level 3 Package:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97fba20e0e6970cbc6551463bc3e1711
https://resolver.caltech.edu/CaltechAUTHORS:20230420-698969800.9
https://resolver.caltech.edu/CaltechAUTHORS:20230420-698969800.9
