Zobrazeno 1 - 10
of 133
pro vyhledávání: '"David P. Millar"'
Autor:
David P. Millar
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
DNA polymerases are intrinsically dynamic macromolecular machines. The purpose of this review is to describe the single-molecule Förster resonance energy transfer (smFRET) methods that are used to probe the conformational dynamics of DNA polymerases
Externí odkaz:
https://doaj.org/article/1c574943bbf74f059f5963d88d1ca949
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract Extreme short-duration rainfall is intensifying with climate warming, and growing evidence suggests that subhourly rainfall extremes are increasing faster than more widely studied durations at hourly and daily timescales. In this case study,
Externí odkaz:
https://doaj.org/article/07ce74ceb29a42c3acea823bbb09eb7a
Publikováno v:
eLife, Vol 10 (2021)
Replication and repair of genomic DNA requires the actions of multiple enzymatic functions that must be coordinated in order to ensure efficient and accurate product formation. Here, we have used single-molecule FRET microscopy to investigate the phy
Externí odkaz:
https://doaj.org/article/8497dd7c5ad04430a6d77330c89d932c
Publikováno v:
Nucleic Acids Research
Immobile four-way junctions (4WJs) are core structural motifs employed in the design of programmed DNA assemblies. Understanding the impact of sequence on their equilibrium structure and flexibility is important to informing the design of complex DNA
Autor:
Raya Al-Shawi, Glenys A. Tennent, David J. Millar, Angela Richard-Londt, Sebastian Brandner, David J. Werring, J. Paul Simons, Mark B. Pepys
Publikováno v:
Open Biology, Vol 6, Iss 2 (2016)
Human amyloid deposits always contain the normal plasma protein serum amyloid P component (SAP), owing to its avid but reversible binding to all amyloid fibrils, including the amyloid β (Aβ) fibrils in the cerebral parenchyma plaques and cerebrovas
Externí odkaz:
https://doaj.org/article/f396179e10544602bce8dcc7789466b1
Publikováno v:
The FASEB Journal. 35
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Replication and repair of genomic DNA requires the action of multiple enzymatic functions that must be coordinated in order to ensure efficient and accurate product formation. Here we have used single-molecule FRET microscopy to investigate the physi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb941b3961ba0955fcb14a9051540348
https://doi.org/10.1101/2020.08.12.248633
https://doi.org/10.1101/2020.08.12.248633
Autor:
Silver Jõemetsa, Anne X. Zhou, Raymond F. Pauszek, Arishma R. Singh, Jonathan Kitzrow, Karin Musier-Forsyth, David P. Millar
Publikováno v:
Biophysical Journal. 121:482a
Autor:
Dirk Hoffmann, Doreen Schwarck, Carina Banning, Matthias Brenner, Lakshmikanth Mariyanna, Marcel Krepstakies, Michael Schindler, David P Millar, Joachim Hauber
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38305 (2012)
The HIV-1 Rev trans-activator is a nucleocytoplasmic shuttle protein that is essential for virus replication. Rev directly binds to unspliced and incompletely spliced viral RNA via the cis-acting Rev Response Element (RRE) sequence. Subsequently, Rev
Externí odkaz:
https://doaj.org/article/8a9ce89e9c834484907729324b97e6c3