Zobrazeno 1 - 10
of 47
pro vyhledávání: '"David P. J. Turner"'
Autor:
Luke R. Green, Ali A. Al-Rubaiawi, Mohammad A. R. M. Al-Maeni, Odile B. Harrison, Matthew Blades, Neil J. Oldfield, David P. J. Turner, Martin C. J. Maiden, Christopher D. Bayliss
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT Host persistence of bacteria is facilitated by mutational and recombinatorial processes that counteract loss of genetic variation during transmission and selection from evolving host responses. Genetic variation was investigated during persi
Externí odkaz:
https://doaj.org/article/742797ecf880443b9021ddd535f6ff03
Autor:
Neelam Dave, Raed S. Albiheyri, Joseph J. Wanford, Luke R. Green, Neil J. Oldfield, David P. J. Turner, Luisa Martinez-Pomares, Christopher D. Bayliss
Publikováno v:
Microbiology. 169
Colonization of mucosal tissues by Neisseria meningitidis requires adhesion mediated by the type IV pilus and multiple outer-membrane proteins. Penetration of the mucosa and invasion of epithelial cells are thought to contribute to host persistence a
Autor:
Robert H Shaw, Xinxue Liu, Arabella S V Stuart, Melanie Greenland, Parvinder K Aley, Nick J Andrews, J Claire Cameron, Sue Charlton, Elizabeth A Clutterbuck, Andrea M Collins, Wanwisa Dejnirattisai, Tanya Dinesh, Saul N Faust, Daniela M Ferreira, Adam Finn, Christopher A Green, Bassam Hallis, Paul T Heath, Helen Hill, Teresa Lambe, Rajeka Lazarus, Vincenzo Libri, Fei Long, Yama F Mujadidi, Emma L Plested, Ella R Morey, Samuel Provstgaard-Morys, Maheshi N Ramasamy, Mary Ramsay, Robert C Read, Hannah Robinson, Gavin R Screaton, Nisha Singh, David P J Turner, Paul J Turner, Iason Vichos, Laura L Walker, Rachel White, Jonathan S Nguyen-Van-Tam, Matthew D Snape, Alasdair P.S. Munro, Jazz Bartholomew, Laura Presland, Sarah Horswill, Sarah Warren, Sophie Varkonyi-Clifford, Stephen Saich, Kirsty Adams, Marivic Ricamara, Nicola Turner, Nicole Y. Yee Ting, Sarah Whittley, Tommy Rampling, Amisha Desai, Claire H. Brown, Ehsaan Qureshi, Karishma Gokani, Kush Naker, Johanna K. Kellett Wright, Rachel L. Williams, Tawassal Riaz, Florentina D. Penciu, Amy Carson, Claudio Di Maso, Gracie Mead, Elizabeth G. Howe, Mujtaba Ghulam Farooq, Rabiullah Noristani, Xin L. Yao, Neil J. Oldfield, Daniel Hammersley, Sue Belton, Simon Royal, Alberto San Francisco Ramos, Cecilia Hultin, Eva P. Galiza, Rebecca Crook, Marcin Bula, Fred Fyles, Hassan Burhan, Flora Maelin, Elen Hughes, Emmanuel Okenyi
Publikováno v:
Shaw, R H, Liu, X, Stuart, A S V, Greenland, M, Aley, P K, Andrews, N J, Finn, A & Lazarus, R & et, A 2022, ' Effect of priming interval on reactogenicity, peak immunological response, and waning after homologous and heterologous COVID-19 vaccine schedules : exploratory analyses of Com-COV, a randomised control trial ', Lancet Respiratory Medicine, vol. 10, no. 11, pp. 1049-1060 . https://doi.org/10.1016/S2213-2600(22)00163-1
Background Priming COVID-19 vaccine schedules have been deployed at variable intervals globally, which might influence immune persistence and the relative importance of third-dose booster programmes. Here, we report exploratory analyses from the Com-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ed4ea510bf1be44fbc2afbfb9cf0590
https://eprints.soton.ac.uk/456454/
https://eprints.soton.ac.uk/456454/
Autor:
Jordan R. Barrett, Adam Finn, Julie Furze, Rajeka Lazarus, Robert Aley, Emma Plested, Nicholas Byard, Alison M. Lawrie, Jack E. Saunders, Catherine C. Smith, Katie J. Ewer, Hannah Davies, Amber Thompson, Jonathan Kwok, Danielle Woods, Luke Blackwell, M N Ramasamy, Wanwisa Dejnirattisai, Hannah Roberts, Conor Whelan, Elizabeth F Jones, Vincenzo Libri, Mutjaba Ghulam Farooq, D Jenkin, D Bellamy, Mimi M. Hou, Alexander D. Douglas, Sarah Kelly, Adrian V. S. Hill, Sarah C. Gilbert, Christine S. Rollier, Megan Baker, Matthew Rajan, Liaquat Khan, E. Thomson, Amy Boyd, Rebecca Beckley, Phillip Baker, Stanislava Koleva, Louise Bates, Simon Kerridge, David J. Smith, Emma Francis, Christina Dold, Brian Angus, Christopher J A Duncan, Raquel Lopez Ramon, Andrew Smith, Alice Bridges-Webb, Thomas C. Hart, R Song, O Mazur, L Silva-Reyes, Claudio Di Maso, Rabiullah Noristani, Patrick J. Lillie, Marco Polo Peralta Alvarez, Matthew D. Snape, Wendy E.M. Crocker, Patrick Kinch, Charles H. Brown, Jasmin Kinch, Angela M. Minassian, M Bittaye, Jilly Muller, Emma V. Sheehan, J Aboagye, Anna L. Goodman, Iain Turnbull, Julia L. Marshall, Kirsten Beadon, Tanya Dinesh, R Makinson, Hannah Sharpe, Indra Rudiansyah, Jade Keen, Yama F Mujadidi, Laura L. Walker, Marta Ulaszewska, Baktash Khozoee, Jonathan Bell, Cameron Bissett, Robert Shaw, E Howe, Amy Beveridge, Cheryl Turner, Holly Smith, Karly Tang, Federica Cappuccini, Syed Adlou, Juthathip Mongkolsapaya, Estée M. Török, Spyridoula Marinou, Joanne McEwan, Rachel Cooper, David P. J. Turner, Merin Thomas, Tonia M. Thomas, Nicola Greenwood, Gavin R. Screaton, Sally Felle, S Bibi, Carla Ferreira Da Silva, P M Folegatti, Jolynne Mokaya, Sophia Hawkins, Elizabeth A. Clutterbuck, Ian D. Poulton, Andy Yao, Reece Mabbett, Christopher A Green, Emma Marlow, Mark Toshner, Heather Bletchly, Alexandra J. Spencer, Rebecca K. Sutherland, Leila Godfrey, Eva P. Galiza, Sarah Williams, Andrew J. Pollard, Saul N. Faust, Grace Li, Mwila Kasanyinga, Nicola Howell, Aabidah Ali, Daisy Harrison, Thomas C. Darton, Samiullah Seddiqi, David J. Kerr, Gertraud Morshead, Rachael Drake-Brockman, Aline Linder, Jamie Fowler, Sandra Belij-Rammerstorfer, Susana Camara, Colin W. Larkworthy, Sophie Davies, Marion E. Watson, Parvinder K. Aley, Bryn Horsington, Sean C. Elias, Adam J. Ritchie, Nelly Owino, David Pulido-Gomez, Michelle Fuskova, Alastair McGregor, Hannah Robinson, Fei Long, Rachel Anslow, Karen J. Ford, Daniela M. Ferreira, Katherine R. W. Emary, Ella Morey, Amy Flaxman, Paul T. Heath, Katrina M Pollock, Liliana Cifuentes Gutierrez, Samuel Provstgaard-Morys, Arabella Stuart, Helen Sanders, Anna Szigeti, Rachel White, Francesca R. Donnellan, Catherine M. Green, Katherine Sanders, N G Marchevsky, Andrea M. Collins, Merryn Voysey, Kushalinii Hillson, Teresa Lambe, Philomena Mweu, Chris Williams, Iason Vichos, Daniel B. Wright, Carina Citra Dewi Joe, Tesfaye Demissie, Rose Trivett, Richard Morter, Helen Hill, Judith Davies, Emily A. Lees, Nisha Singh, Ana Gibertoni Cruz, P Cicconi, Abigail Platt, Fernando Ramos Lopez, Nguyen Tran
Publikováno v:
Lancet (London, England)
Background COVID-19 vaccine supply shortages are causing concerns about compromised immunity in some countries as the interval between the first and second dose becomes longer. Conversely, countries with no supply constraints are considering administ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9942f9b6ea936cc7be0ba9e053573ebf
http://hdl.handle.net/10044/1/92023
http://hdl.handle.net/10044/1/92023
Autor:
Sophie Varkonyi-Clifford, Sue Charlton, Anna England, Matthew D. Snape, Parvinder K. Aley, Elizabeth A. Clutterbuck, Pauline Ambrose, Eva P. Galiza, Adam Finn, Laura L. Walker, Emma Plested, Ehsaan Qureshi, Chanice Knight, David P. J. Turner, Lisa Hitchins, Mujtaba Ghulam Farooq, Christopher A Green, Melanie Greenland, J. Claire Cameron, Stephanie Leung, Karen Buttigieg, Jonathan S. Nguyen-Van-Tam, Cecilia Hultin, Florentina D Penciu, Jazz Bartholomew, Yama F Mujadidi, Nisha Singh, Sarah Horswill, Tommy Rampling, Kush Naker, Rabiullah Noristani, Xinxue Liu, Marivic Ricamara, Tawassal Riaz, Phill Brown, Rajeka Lazarus, Imam Shaik, Johanna K Kellett Wright, Kerry Godwin, Kelly Davies, Robert Shaw, Paminder Lall, Neil J. Oldfield, Farah Shiham, Sue Belton, Karishma Gokani, Carla Solórzano, Mary Ramsay, Kirsty Adams, Ross Fothergill, Hannah Robinson, Claudio Di Maso, Rachel Williams, Lauren Allen, Paul T. Heath, Sarah Whittley, Stephen Saich, E Howe, Bassam Hallis, Alberto San Francisco Ramos, Simon Royal, Alasdair Munro, Tanya Dinesh, Vincenzo Libri, Helen Hill, Arabella Stuart, Samuel Provstgaard-Morys, Xin L Yao, Andrea M. Collins, Rachel White, Paul Turner, Teresa Lambe, Nick Andrews, Iason Vichos, Daniela M. Ferreira, Natalie Baker, Nicole Y Yee Ting, Claire Brown, M N Ramasamy, Sarah Warren, Amisha Desai, Fei Long, Laura Presland, Hannah Sainsbury, Daniel Hammersley, Saul N. Faust, Robert C. Read, Nicola Turner
Publikováno v:
Lancet (London, England)
Snape, M D 2021, ' Safety and immunogenicity of heterologous versus homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine (Com-COV) : a single-blind, randomised, non-inferiority trial ', Lancet, vol. 398, no. 10303, pp. 856-869 . https://doi.org/10.1016/S0140-6736(21)01694-9
Snape, M D 2021, ' Safety and immunogenicity of heterologous versus homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine (Com-COV) : a single-blind, randomised, non-inferiority trial ', Lancet, vol. 398, no. 10303, pp. 856-869 . https://doi.org/10.1016/S0140-6736(21)01694-9
Background Use of heterologous prime-boost COVID-19 vaccine schedules could facilitate mass COVID-19 immunisation. However, we have previously reported that heterologous schedules incorporating an adenoviral vectored vaccine (ChAdOx1 nCoV-19, AstraZe
Autor:
David P. J. Turner, Luke R. Green, Christopher D. Bayliss, Jay Lucidarme, Neil J. Oldfield, Ray Borrow, Adeolu B. Adewoye, Neelam Dave, Stephen Clark
Publikováno v:
The Journal of Infectious Diseases
Background Since 2009, increases in the incidence of invasive meningococcal disease have occurred in the United Kingdom due to a sublineage of the Neisseria meningitidis serogroup W ST-11 clonal complex (hereafter, the “original UK strain”). In 2
Autor:
Beth Blane, P Cicconi, Katherine R. W. Emary, Catherine M. Green, Melanie Greenland, Adrian V. S. Hill, Sarah C. Gilbert, Rajeka Lazarus, N G Marchevsky, Cristina V. Ariani, Daniela M. Ferreira, Amy Flaxman, Yama F Mujadidi, Teresa Lambe, Eva P. Galiza, E. Thomson, Helen Hill, Adam Finn, Sue Charlton, Katie J. Ewer, Mark Toshner, Simon Kerridge, Paul T. Heath, D Jenkin, Shuo Feng, Christina Dold, Catherine Ludden, Thomas C. Darton, Christopher Williams, Parvinder K. Aley, R Song, Rebecca K. Sutherland, Matthew D. Snape, Alexander D. Douglas, M N Ramasamy, Andrea M. Collins, Johan Vekemans, Hannah Robinson, Daniel J. Phillips, Angela M. Minassian, P M Folegatti, Elizabeth A. Clutterbuck, Christopher A Green, Tonya Villafana, Merryn Voysey, Vincenzo Libri, Anna L. Goodman, Emma Plested, S Bibi, Brian Angus, Christopher J A Duncan, Saul N. Faust, Andrew Smith, Patrick J. Lillie, Bassam Hallis, Tony Cox, Andrew J. Pollard, Jodie Hay, Tanya Golubchik, David P. J. Turner, Michelle Fuskova, Alastair McGregor, David Bonsall, Katrina M Pollock
Publikováno v:
Lancet (London, England)
Emary, K R W, Golubchik, T, Aley, P K, Ariani, C V, Angus, B, Bibi, S, Finn, A, Lazarus, R, Smith, A, Pollard, A J & et. al. 2021, ' Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 variant of concern 202012/01 (B.1.1.7) : an exploratory analysis of a randomised controlled trial ', Lancet, vol. 397, no. 10282, pp. 1351-1362 . https://doi.org/10.1016/S0140-6736(21)00628-0
Emary, K R W, Golubchik, T, Aley, P K, Ariani, C V, Angus, B, Bibi, S, Finn, A, Lazarus, R, Smith, A, Pollard, A J & et. al. 2021, ' Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 variant of concern 202012/01 (B.1.1.7) : an exploratory analysis of a randomised controlled trial ', Lancet, vol. 397, no. 10282, pp. 1351-1362 . https://doi.org/10.1016/S0140-6736(21)00628-0
Background A new variant of SARS-CoV-2, B.1.1.7, emerged as the dominant cause of COVID-19 disease in the UK from November, 2020. We report a post-hoc analysis of the efficacy of the adenoviral vector vaccine, ChAdOx1 nCoV-19 (AZD1222), against this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faa74c02afd2a33e6fd74baf40b04b0f
http://hdl.handle.net/10044/1/89705
http://hdl.handle.net/10044/1/89705
Autor:
David P. J. Turner, Daniela M. Ferreira, Nisha Singh, Bassam Hallis, Xinxue Liu, Nick Andrews, Helen Hill, Robert Shaw, Fei Long, Adam Finn, Parvinder K. Aley, Elizabeth A. Clutterbuck, Emma Plested, Arabella Stuart, Paul Turner, Robert C. Read, Christopher A Green, Mary Ramsay, Andrea M. Collins, M N Ramasamy, Rajeka Lazarus, Tanya Dinesh, Samuel Provstgaard-Morys, Vincenzo Libri, Paul T. Heath, J. Claire Cameron, Rachel White, Melanie Greenland, Teresa Lambe, Matthew D. Snape, Saul N. Faust, Laura L. Walker, Yama F Mujadidi, Jonathan S. Nguyen-Van-Tam, Hannah Robinson
Publikováno v:
SSRN Electronic Journal.
Background: Use of heterologous prime-boost COVID-19 vaccine schedules could facilitate mass COVID-19 immunisation, however we have previously reported that heterologous schedules incorporating an adenoviral-vectored vaccine (ChAd, Vaxzevria, Astraze
Autor:
Merryn Voysey, Sue Ann Costa Clemens, Shabir A. Madhi, Lily Yin Weckx, Pedro M. Folegatti, Parvinder K. Aley, Brian John Angus, Vicky Baillie, Shaun L. Barnabas, Qasim E. Bhorat, Sagida Bibi, Carmen Briner, Paola Cicconi, Elizabeth Clutterbuck, Andrea M. Collins, Clare Cutland, Thomas Darton, Keertan Dheda, Alexander D. Douglas, Christopher J. A. Duncan, Katherine R. W. Emary, Katie Ewer, Amy Flaxman, Lee Fairlie, Saul N. Faust, Shuo Feng, Daniela M. Ferreira, Adam Finn, Eva Galiza, Anna L. Goodman, Catherine M. Green, Christopher A. Green, Melanie Greenland, Catherine Hill, Helen C. Hill, Ian Hirsch, Alane Izu, Daniel Jenkin, Simon Kerridge, Anthonet Koen, Gaurav Kwatra, Rajeka Lazarus, Vincenzo Libri, Patrick J. Lillie, Natalie G. Marchevsky, Richard P. Marshall, Ana Verena Almeida Mendes, Eveline P. Milan, Angela M. Minassian, Alastair C. McGregor, Yama Farooq Mujadidi, Anusha Nana, Sherman D. Payadachee, Daniel J. Phillips, Ana Pittella, Emma Plested, Katrina M. Pollock, Maheshi N. Ramasamy, Hannah Robinson, Alexandre V. Schwarzbold, Andrew Smith, Rinn Song, Matthew D. Snape, Eduardo Sprinz, Rebecca K. Sutherland, Emma C. Thomson, Mili Torok, Mark Toshner, David P. J. Turner, Johan Vekemans, Tonya L. Villafana, Thomas White, Christopher J. Williams, Adrian V. S. Hill, Teresa Lambe, Sarah C. Gilbert, Andrew Pollard, Oxford COVID Vaccine Trial Group
Publikováno v:
SSRN Electronic Journal.
Background: The ChAdOx1 nCoV-19 (AZD1222) vaccine has been approved for emergency use by the UK regulatory authority, MHRA, with a regimen of two standard doses given with an interval of between 4 and 12 weeks. The planned rollout in the UK will invo
Autor:
Katherine R. W. Emary, Tanya Golubchik, Parvinder K. Aley, Cristina V. Ariani, Brian John Angus, Sagida Bibi, Beth Blane, David Bonsall, Paola Cicconi, Sue Charlton, Elizabeth Clutterbuck, Andrea M. Collins, Tony Cox, Thomas Darton, Christina Dold, Alexander D. Douglas, Christopher J. A. Duncan, Katie Ewer, Amy Flaxman, Saul N. Faust, Daniela M. Ferreira, Shuo Feng, Adam Finn, Pedro M. Folegatti, Michelle Fuskova, Eva Galiza, Anna L. Goodman, Catherine M. Green, Christopher A. Green, Melanie Greenland, Bassam Hallis, Paul T. Heath, Jodie Hay, Helen C. Hill, Daniel Jenkin, Simon Kerridge, Rajeka Lazarus, Vincenzo Libri, Patrick J. Lillie, Catherine Ludden, Natalie G. Marchevsky, Angela M. Minassian, Alastair C. McGregor, Yama Farooq Mujadidi, Daniel J. Phillips, Emma Plested, Katrina M. Pollock, Hannah Robinson, Andrew Smith, Rinn Song, Matthew D. Snape, Rebecca K. Sutherland, Emma C. Thomson, Mark Toshner, David P. J. Turner, Johan Vekemans, Tonya L. Villafana, Christopher J. Williams, Adrian V. S. Hill, Teresa Lambe, Sarah C. Gilbert, Merryn Voysey, Maheshi N. Ramasamy, Andrew Pollard, Oxford COVID Vaccine Trial Group
Publikováno v:
SSRN Electronic Journal.
Background: A new variant of SARS-CoV-2, B.1.1.7, emerged as the dominant cause of COVID-19infection in the United Kingdom from November 2020 with a transmission advantage over the previous variants of the virus. Here we report efficacy of the adenov