Zobrazeno 1 - 10
of 63
pro vyhledávání: '"David P. Hart"'
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 6, Iss 4, Pp 100521- (2024)
Objective: To develop a novel scoring system to characterize osteoarthritis-related degeneration distinct from spontaneous subchondral bone lesions observed in the tibia and femur of male Sprague Dawley rats. Method: Knee joints from male rats follow
Externí odkaz:
https://doaj.org/article/17f74ff2d3ee44b9b55f37e4d30d13e6
Publikováno v:
Regenerative Therapy, Vol 26, Iss , Pp 124-131 (2024)
Treatments for articular cartilage injuries are still challenging, due in part to its avascular and aneural surroundings. Since the first report of autologous chondrocyte implantation, cell-based therapies have been extensively studied with a variety
Externí odkaz:
https://doaj.org/article/d4caba76b41c48ea94fdd00b1c9d56b7
Autor:
Kelsey H. Collins, Graham Z. MacDonald, David A. Hart, Ruth A. Seerattan, Jaqueline L. Rios, Raylene A. Reimer, Walter Herzog
Publikováno v:
Journal of Sport and Health Science, Vol 9, Iss 2, Pp 132-139 (2020)
Background: Osteoarthritis is one of the leading causes of pain and disability worldwide, and a large percentage of patients with osteoarthritis are individuals who are also obese. In recent years, a series of animal models have demonstrated that obe
Externí odkaz:
https://doaj.org/article/77e94bf393d9407db8367c25e7bf1347
Publikováno v:
European Medical Journal, Vol 4, Iss 1, Pp 63-70 (2019)
Obesity is known to affect a high percentage of both adults and children in developed countries. Individuals with obesity are at risk of developing a number of comorbidities, as well as metabolic syndrome, which can create a low-grade systemic inflam
Externí odkaz:
https://doaj.org/article/f2a3078d331d495ca3278a9206a95197
Autor:
David A. Hart, Ronald F. Zernicke
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
It is widely acknowledged that achieving and maintaining a healthier lifestyle can be enhanced through regular participation in sport and physical activity. Coevally, a growing number of health professionals regard exercise as a legitimate interventi
Externí odkaz:
https://doaj.org/article/9534e8c8941c4145bb4a5bb755b88043
Autor:
Jaqueline Lourdes Rios, Kevin Rudi Boldt, James William Mather, Ruth Anne Seerattan, David Arthur Hart, Walter Herzog
Publikováno v:
Sports Medicine - Open, Vol 4, Iss 1, Pp 1-10 (2018)
Abstract Background Walking and running provide cyclical loading to the knee which is thought essential for joint health within a physiological window. However, exercising outside the physiological window, e.g. excessive cyclical loading, may produce
Externí odkaz:
https://doaj.org/article/f3a2d31d4a5840b3b6e66744d75d3179
Autor:
Kazunori Shimomura, Wataru Ando, Hiromichi Fujie, David A. Hart, Hideki Yoshikawa, Norimasa Nakamura
Publikováno v:
Journal of Experimental Orthopaedics, Vol 5, Iss 1, Pp 1-14 (2018)
Abstract Articular cartilage does not heal spontaneously due to its limited healing capacity, and thus effective treatments for cartilage injuries has remained challenging. Since the first report by Brittberg et al. in 1994, autologous chondrocyte im
Externí odkaz:
https://doaj.org/article/4dede03b9c5245fb9848e0734f7ef8d5
Autor:
David A. Hart
Publikováno v:
European Medical Journal Reproductive Health, Vol 3, Iss 1, Pp 76-83 (2017)
Endometriosis is a chronic condition that affects ˜10% of young women worldwide. Pain and infertility are the two most common features of the disease. The condition appears to be sex hormone-dependent, although a subset of females with the condition
Externí odkaz:
https://doaj.org/article/8d1ff0ae10224781968a2ee009dc38be
Publikováno v:
Stem Cells International, Vol 2019 (2019)
Mesenchymal stem cells (MSCs) have the capacity to differentiate towards bone, fat, and cartilage lineages. The most widely used culture and differentiation protocols for MSCs are currently limited by their use of serum-containing media and small-sca
Externí odkaz:
https://doaj.org/article/3025731a983c4076898b18525044f08b
Autor:
Kelsey H. Collins, Walter Herzog, Graham Z. MacDonald, Raylene A. Reimer, Jaqueline L. Rios, Ian C. Smith, Ronald F. Zernicke, David A. Hart
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Inflammation can arise in response to a variety of stimuli, including infectious agents, tissue injury, autoimmune diseases, and obesity. Some of these responses are acute and resolve, while others become chronic and exert a sustained impact on the h
Externí odkaz:
https://doaj.org/article/72a2a2876a6d4ff38b9122f61036e3f5