Zobrazeno 1 - 10
of 43
pro vyhledávání: '"David P. Gamblin"'
Autor:
Adrian P. Banks, David M. Gamblin
Publikováno v:
Judgment and Decision Making, Vol 17, Pp 1255-1286 (2022)
How do people make everyday decisions in order to achieve the most successful outcome? Decision making research typically evaluates choices according to their expected utility. However, this research largely focuses on abstract or hypothetical tasks
Externí odkaz:
https://doaj.org/article/bcd41fda1512447481ea8e104e6b5d3c
Autor:
John P. Simons, Pierre Çarçabal, Emilio J. Cocinero, E. Cristina Stanca-Kaposta, Conor S. Barry, María del Carmen Fernández-Alonso, David P. Gamblin, Svemir Rudić, Sarah M. Remmert, Benjamin G. Davis
Publikováno v:
Journal of the American Chemical Society
N-glycosylation of eukaryotic proteins is widespread and vital to survival. The pentasaccharide unit −Man3GlcNAc2– lies at the protein-junction core of all oligosaccharides attached to asparagine side chains during this process. Although its abso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::922e2d79d90556ea823a334c6b4ccf3c
https://doi.org/10.1021/ja4056678
https://doi.org/10.1021/ja4056678
Autor:
Mark Dethlefsen, Emilio J. Cocinero, E. Cristina Stanca-Kaposta, Bo Liu, John P. Simons, David P. Gamblin, Benjamin G. Davis
The influence of an acetami- do group in directing the preferred choice of hydration sites in glucosa- mine and a consequent extension of the working rules governing regioselec- tive hydration and conformational choice, have been revealed through com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4f8dc7bd51c1f40d4157380aeb7fdf0
https://doi.org/10.1002/chem.200901830
https://doi.org/10.1002/chem.200901830
In higher organisms, the functions of many proteins are modulated by post-translational modifications (PTMs). Glycosylation is by far the most diverse of the PTM processes. Natural protein production methods typically produce PTM or glycoform mixture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9128b7da6a86de418a094e6a0e8bb8d
https://ora.ox.ac.uk/objects/uuid:55e380d6-f8c5-4218-aba8-436958d2277c
https://ora.ox.ac.uk/objects/uuid:55e380d6-f8c5-4218-aba8-436958d2277c
Autor:
Eoin M. Scanlan, Timothy D. Vaden, Svemir Rudić, David P. Gamblin, Benjamin G. Davis, Ram Sagar, Jack Simons, Timothy D. W. Claridge, Barbara Odell
We present direct investigations of the conformational preferences of sugars with a positively charged substituent at their anomeric centre, C-1, which display in solution, a preference for an equatorial conformation - an apparent reversal of the nor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe6a16d1f8bdedec634b5875ea88c9de
https://doi.org/10.1039/c2sc20341c
https://doi.org/10.1039/c2sc20341c
The direct formation of glycosyl thiols from reducing sugars allows one-pot protein glycoconjugation
(Figure Presented) Sweet and easy: A one-pot method consisting of direct thionation (1) followed by thiol-mediated chemoselective ligation (2) can be used for site-selective protein glycosylation. This procedure, which uses the Lawesson reagent, has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8946e486af88434e9e2f3844234eec19
https://doi.org/10.1002/anie.200600685
https://doi.org/10.1002/anie.200600685
Publikováno v:
Journal of the American Chemical Society. 131:11117-11123
A combination of vibrational spectroscopy conducted under molecular beam conditions and quantum chemical calculation has established the intrinsic three-dimensional structures of the cellulose disaccharide and, focusing on the critical beta1,4-linkag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2973b6e26943daca0802cc475da8677
https://doi.org/10.1021/ja903322w
https://doi.org/10.1021/ja903322w
Autor:
John P. Simons, E. Cristina Stanca-Kaposta, Emilio J. Cocinero, David P. Gamblin, Benjamin G. Davis
Publikováno v:
Tetrahedron: Asymmetry. 20:718-722
The combination of vibrational spectroscopy, conducted in a supersonic jet expansion, with computation through molecular mechanics, density functional theory (DFT) and ab initio calculation, has provided a new approach to the conformational and struc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c118d8918081de4b1ff37f191662d5f
https://doi.org/10.1016/j.tetasy.2009.02.032
https://doi.org/10.1016/j.tetasy.2009.02.032
Publikováno v:
FEBS Journal. 275:1949-1959
Strategies for the chemical construction of synthetic proteins with precisely positioned post-translational modifications or their mimics offer a powerful method for dissecting the complexity of functional protein alteration and the associated comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e3e18b3dd7dfe79c06cab614c4af177
https://doi.org/10.1111/j.1742-4658.2008.06347.x
https://doi.org/10.1111/j.1742-4658.2008.06347.x
Autor:
James Screen, E. Cristina Stanca-Kaposta, David P. Gamblin, Bo Liu, Neil A. Macleod, Lavina C. Snoek, Benjamin G. Davis, John P. Simons
Publikováno v:
Angewandte Chemie. 119:3718-3722
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bf1db7fee0872c415054a9465a9428a
https://doi.org/10.1002/ange.200605116
https://doi.org/10.1002/ange.200605116