Zobrazeno 1 - 10
of 14
pro vyhledávání: '"David P. Blakeman"'
Autor:
Thomas W. Petry, Robert L. Griffin, Raymond F. Krzesicki, Steven D. Aust, Jia En Chin, Timothy P. Ryan, David P. Blakeman, Ivan M. Richards
Publikováno v:
Free Radical Biology and Medicine. 22:901-908
Ferritin is an iron storage protein that is regulated at the transcriptional and translational levels, resulting in a complex mixture of tissue- and condition-specific isoforms. The protein shell of ferritin is composed of 24 subunits of two types (h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d645883dfd2771cbb55f91cb8f838a42
https://doi.org/10.1016/s0891-5849(96)00483-2
https://doi.org/10.1016/s0891-5849(96)00483-2
Publikováno v:
Biochemical Pharmacology. 50:929-935
In a previous report on diquat-dependent oxidative damage in rat hepatic microsomes, protein oxidation, as measured by protein carbonyl (PC) formation, was observed in addition to lipid peroxidation (LP). Both phenomena were antioxidant sensitive. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b18f9057f843bcf5ffe8953d151cfbc9
https://doi.org/10.1016/0006-2952(95)00214-k
https://doi.org/10.1016/0006-2952(95)00214-k
Autor:
Joe W. Davis, Robert A. Jolly, William H. Packwood, Thomas W. Petry, Gerald J. Kolaja, David P. Blakeman
Publikováno v:
Toxicologic Pathology. 23:487-497
S-(1,2-dichlorovinyl)-L-cysteine (DCVC)-induced nephrotoxicity in vivo was investigated in New Zealand White rabbits. A primary emphasis in these studies was further characterization of DCVC-induced nephrotoxicity using a variety of serum and urinary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33384eef6ec7cae5d6cecbb939e0097a
https://doi.org/10.1177/019262339502300405
https://doi.org/10.1177/019262339502300405
Publikováno v:
Journal of medicinal chemistry. 34(3)
The synthesis of N-substituted benzimidazole (H + -K + )-ATPase or proton-pump inhibitors is described. These compounds were prepared to function as prodrugs of the parent N-H compound and evaluated for their ability to inhibit gastric (H + -K + )-AT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2456878abe242a735218513a455ecb6a
https://pubmed.ncbi.nlm.nih.gov/1848293
https://pubmed.ncbi.nlm.nih.gov/1848293
Publikováno v:
Brain research. 521(1-2)
Muscimol-induced 36Cl- uptake in rat cerebrocortical synaptoneurosomes was reduced upon exposure of the membrane sacs to low Na+ media. This Na+ requirement led us to examine the role of the Na(+)-dependent gamma-aminobutyric acid (GABA) transport sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01df0e9e67efcc5fc965b2e9e61fe60d
https://pubmed.ncbi.nlm.nih.gov/2169957
https://pubmed.ncbi.nlm.nih.gov/2169957
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 845:54-59
We have examined the interaction of omeprazole, a gastric antisecretory agent, with endogenous or exogenous sulfhydryl compounds in isolated rabbit gastric glands. The glands exposed to omeprazole (2 μM for 50 min) could recover acid secretory respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d68efc2b7e3319938239595d1fe3250
https://doi.org/10.1016/0167-4889(85)90054-0
https://doi.org/10.1016/0167-4889(85)90054-0
Autor:
J.P. Davis, Mindy M. Tai, David P. Blakeman, Heidi A. Zurcher-Neely, Robert L. Heinrikson, Wha Bin Im
Publikováno v:
Biochemistry. 28:3183-3187
Limited tryptic digestion of fluorescein isothiocyanate (FITC)-labeled (H+-K+)-ATPase from rat resting light gastric membranes produced a soluble 27-kDa polypeptide which retained the fluorescence of the parent enzyme. Its production was markedly enh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2caf1e4d59ca2799cbb83ac46797e292
https://doi.org/10.1021/bi00434a011
https://doi.org/10.1021/bi00434a011
Autor:
Wha Bin Im, David P. Blakeman
Publikováno v:
Biochemical and Biophysical Research Communications. 108:635-639
Rat gastric membranes enriched in (H+-K+)-ATPase, when prepared in the presence of 1 m M ethyleneglycol-bis-(β-aminoethyl ether)N,N′-tetraacetic acid, showed the ability to accumulate H+ ions upon addition of ATP, KCl, and valinomycin. The membran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1a56ce306b4f7df52b419ee3c7d33e3
https://doi.org/10.1016/0006-291x(82)90876-2
https://doi.org/10.1016/0006-291x(82)90876-2
Publikováno v:
Biochemical and Biophysical Research Communications. 163:611-617
ConA-sepharose and polylysine-agarose beads effectively bound detergent-solubilized GABAA receptors from rat cerebrocortical membranes. The immobilized receptors showed a single class of high affinity binding sites specific for flunitrazepam or musci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bb4ac438c2023d578cbf9d6d00eab56
https://doi.org/10.1016/0006-291x(89)92181-5
https://doi.org/10.1016/0006-291x(89)92181-5
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 772:167-175
We have examined histamine- or carbachol-induced changes in rat gastric membranes enriched in K+-stimulated ATPase. Stimulation of secretion by both secretagogues in vivo produced a class of microsomal membranes which exhibited valinomycin-independen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9615dd4fdc4ce17a7b95ffa8a0ed55a4
https://doi.org/10.1016/0005-2736(84)90040-3
https://doi.org/10.1016/0005-2736(84)90040-3