Zobrazeno 1 - 10
of 54
pro vyhledávání: '"David P. Andrews"'
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background At the beginning of the COVID-19 pandemic, some workers had the opportunity to work from home, while others remained in on-site work. The aim of the present study was to compare the psychosocial work aspects, work ability, mental
Externí odkaz:
https://doaj.org/article/0d71ea4084664b82a85e86f3726df993
Autor:
Diandra Zipinotti dos Santos, Mohamad Elbaz, Emily Branchard, Wiebke Schormann, Carla E. Brown, Autumn R. Meek, Vincent C.O. Njar, Robert J. Hamilton, Mark A. Reed, David W. Andrews, Linda Z. Penn
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 116934- (2024)
There is an urgent need to provide immediate and effective options for the treatment of prostate cancer (PCa) to prevent progression to lethal castration-resistant PCa (CRPC). The mevalonate (MVA) pathway is dysregulated in PCa, and statin drugs comm
Externí odkaz:
https://doaj.org/article/699af22ca7604478ae0e47c46ba49ef6
Autor:
Martin Cottet, Yuniel Fernandez Marrero, Simon Mathien, Karine Audette, Raphaelle Lambert, Eric Bonneil, Kenneth Chng, Alex Campos, David W. Andrews
Publikováno v:
SLAS Discovery, Vol 29, Iss 3, Pp 100121- (2024)
High-content imaging approaches, in combination with the use of perturbing agents such as small molecules or CRISPR-driven gene editing, have widely contributed to the identification of new therapeutic compounds. Thanks to recent advances in image-an
Externí odkaz:
https://doaj.org/article/5564449d6c78415e9c5915e263f7b2df
Publikováno v:
Applied Sciences, Vol 14, Iss 16, p 7008 (2024)
It is well established that the interaction of light with matter generally imparts mechanical forces and associated torques. Where laser light is involved, such effects can be deployed for the microscale and nanoscale manipulation of matter, giving r
Externí odkaz:
https://doaj.org/article/b9ae8985b6b04accadb5434d8b7de23a
Autor:
Brandon T. Wallace, David L. Andrews
Publikováno v:
Social Sciences, Vol 13, Iss 8, p 383 (2024)
This discussion critically examines and questions assumptions about the meanings and motivations of sporting consumption. We argue that the practice of sneaker customization demonstrates the contested terrain of sporting consumption, wherein contempo
Externí odkaz:
https://doaj.org/article/6d85bc179b8f44a29e37aeb85f756515
Autor:
Jenna E. van Leeuwen, Wail Ba-Alawi, Emily Branchard, Jennifer Cruickshank, Wiebke Schormann, Joseph Longo, Jennifer Silvester, Peter L. Gross, David W. Andrews, David W. Cescon, Benjamin Haibe-Kains, Linda Z. Penn, Deena M. A. Gendoo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Statins are promising for breast cancer therapy; dipyridamole can potentiate their effects, but is contraindicated in some cases. Here, the authors develop a pharmacogenomics pipeline to predict other compounds that potentiate statins, and validate t
Externí odkaz:
https://doaj.org/article/f57984f909454f0787ee786ab65589d9
Autor:
Lorenzo Galluzzi, Jenny Zilberberg, Amelia Zellander, Kenneth Kirby, Christopher Uhl, Christopher Cultrara, Essam Abed Elrazaq, David W Andrews, Charles B Scott, Mark A Exley
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 8 (2023)
Background IGV-001 is a personalized, autologous cancer cell-based immunotherapy conceived to deliver a tumor-derived antigenic payload in the context of immunostimulatory signals to patients with glioblastoma (GBM). IGV-001 consists of patient-deriv
Externí odkaz:
https://doaj.org/article/4dcff276a1bf4922837be3e5877e9195
Autor:
Fernanda Cabegi de Barros, Cristiane Shinohara Moriguchi, Thaís Cristina Chaves, David M. Andrews, Michael Sonne, Tatiana de Oliveira Sato
Publikováno v:
BMC Musculoskeletal Disorders, Vol 23, Iss 1, Pp 1-12 (2022)
Abstract Background Most ergonomics studies on office workstations evaluate the effects of an intervention only by subjective measures such as musculoskeletal pain and discomfort. Limited evidence has been provided regarding risk factor reduction in
Externí odkaz:
https://doaj.org/article/559bb7fc3ad44b7584259f182348fcaf
Autor:
James M Pemberton, Dang Nguyen, Elizabeth J Osterlund, Wiebke Schormann, Justin P Pogmore, Nehad Hirmiz, Brian Leber, David W Andrews
Publikováno v:
eLife, Vol 12 (2023)
Anti-apoptotic proteins such as BCL-XL promote cell survival by sequestering pro-apoptotic BCL-2 family members, an activity that frequently contributes to tumorigenesis. Thus, the development of small-molecule inhibitors for anti-apoptotic proteins,
Externí odkaz:
https://doaj.org/article/c46858294f8f416e96855c98bce4cf03
Autor:
Claudia M Town, Danielle L Gyemi, Zoe Ellis, Charles Kahelin, Andrew C Laing, David M Andrews
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0283012 (2023)
Soft tissues overlying the hip play a critical role in protecting against fractures during fall-related hip impacts. Consequently, the development of an efficient and cost-effective method for estimating hip soft tissue thicknesses in living people m
Externí odkaz:
https://doaj.org/article/908b861977b94a018c14c985dee8beb6