Fast estimation of adult cerebral blood content and oxygenation with hyperspectral time-resolved near-infrared spectroscopy

Autor: David Jonathan Fulop Cohen, Natalie C. Li, Seva Ioussoufovitch, Mamadou Diop

Publikováno v: Frontiers in Neuroscience, Vol 17 (2023)

Near-infrared spectroscopy (NIRS) can measure tissue blood content and oxygenation; however, its use for adult neuromonitoring is challenging due to significant contamination from their thick extracerebral layers (ECL; primarily scalp and skull). Thi

Externí odkaz: https://doaj.org/article/79a8c50bc6fe4a3c92ec01811256bb3f

Mathematical Modelling of Molecular Pathways Enabling Tumour Cell Invasion and Migration.

Autor: David P A Cohen, Loredana Martignetti, Sylvie Robine, Emmanuel Barillot, Andrei Zinovyev, Laurence Calzone

Publikováno v: PLoS Computational Biology, Vol 11, Iss 11, p e1004571 (2015)

Understanding the etiology of metastasis is very important in clinical perspective, since it is estimated that metastasis accounts for 90% of cancer patient mortality. Metastasis results from a sequence of multiple steps including invasion and migrat

Externí odkaz: https://doaj.org/article/7f3466bb9dbf4b3a9315369251d6c820

NaviCell Web Service for network-based data visualization

Autor: Inna Kuperstein, David P. A. Cohen, Eric Viara, Laurence Calzone, Eric Bonnet, Emmanuel Barillot, Andrei Zinovyev

Publikováno v: Nucleic Acids Research

Data visualization is an essential element of biological research, required for obtaining insights and formulating new hypotheses on mechanisms of health and disease. NaviCell Web Service is a tool for network-based visualization of ‘omics’ data

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e5a91ab86192bd6b7eb90cbcbf777ac
https://doi.org/10.1093/nar/gkv450

Encyclopedia of Autographa californica nucleopolyhedrovirus genes

Autor: Martin Marek, Monique M. van Oers, Just M. Vlak, Bryn G. Davies, David P. A. Cohen

Publikováno v: Virologica Sinica. 24:359-414

The Autographa californica multiple capsid nucleopolyhedrovirus (AcMNPV) was the first baculovirus for which the complete nucleotide sequence became known. Since then 15 years lapsed and much research has been performed to elucidate putative function

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4f7bdff14a9646c844fd81242734ef72
https://doi.org/10.1007/s12250-009-3059-7

Concomitant Notch activation and p53 deletion trigger epithelial-to-mesenchymal transition and metastasis in mouse gut

Autor: Elodie Girard, Emmanuel Barillot, Perrine Paul-Gilloteaux, Silvia Fre, Silvina Dos Reis Tavares, David P. A. Cohen, Maia Chanrion, Andrei Zinovyev, Luc Fetler, Lev Stimmer, Ivan Bièche, Patricia Legoix-Né, Cédric Barrière, Danijela Matic Vignjevic, Sylvie Robine, Inna Kuperstein, Loredana Martignetti, Daniel Louvard, Giuseppe-Fulvio Boccia, Didier Meseure, Fatima El Marjou, Wulfran Cacheux

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2014, 5, pp.5005. ⟨10.1038/ncomms6005⟩
Nature Communications, 2014, 5, pp.5005. ⟨10.1038/ncomms6005⟩

Epithelial-to-mesenchymal transition-like (EMT-like) is a critical process allowing initiation of metastases during tumour progression. Here, to investigate its role in intestinal cancer, we combine computational network-based and experimental approa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7c3b12a1274e3ab76b1f60e63f2072e
https://doi.org/10.1038/ncomms6005