Zobrazeno 1 - 10
of 66
pro vyhledávání: '"David P Walling"'
Autor:
Wenyan Wang, Xiaofeng Wang, Ying Dong, David P. Walling, Pinglan Liu, Wanhui Liu, Yanan Shi, Kaoxiang Sun
Publikováno v:
Neurology and Therapy, Vol 13, Iss 2, Pp 355-372 (2024)
Abstract Introduction RYKINDO® (Rykindo) is a novel, long-acting injectable risperidone formulation administered biweekly (Q2W) through intramuscular gluteal injection for the treatment of schizophrenia in adult patients. This analysis was conducted
Externí odkaz:
https://doaj.org/article/eb5a4c92c10c427c9cebda73cdd8fb85
Autor:
Swan Lin, Adrian Ionescu, Jessica Maynard‐Scott, Mike Kennedy, David P. Walling, Maura Furey, Jaskaran B. Singh
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 5, Pp n/a-n/a (2024)
Abstract This parallel‐arm, phase I study investigated the potential cytochrome P450 (CYP)3A induction effect of NBI‐1065845 (TAK‐653), an investigational α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor potentiator
Externí odkaz:
https://doaj.org/article/d8dda4c355984c7ab692d6b9e5887b55
Autor:
Henry A. Nasrallah, Peter J. Weiden, David P. Walling, Yangchun Du, Baiyun Yao, Sergey Yagoda, Amy Claxton
Publikováno v:
BMC Psychiatry, Vol 21, Iss 1, Pp 1-13 (2021)
Abstract Background A randomized, controlled, phase 3b study (ALPINE) evaluated efficacy and safety of a 2-month formulation of aripiprazole lauroxil (AL) using a 1-day initiation regimen in patients hospitalized for an acute exacerbation of schizoph
Externí odkaz:
https://doaj.org/article/eadc67c7e7c04be7af8d394b3a87cbf9
Autor:
Daniel Umbricht, Markus Abt, Paul Tamburri, Christopher Chatham, Štefan Holiga, Michael J. Frank, Anne G.E. Collins, David P. Walling, Rick Mofsen, Daniel Gruener, Lev Gertsik, Jeff Sevigny, Sanjay Keswani, Juergen Dukart
Publikováno v:
Biological Psychiatry Global Open Science, Vol 1, Iss 1, Pp 70-77 (2021)
Background: Reduced activation of dopamine D1 receptor signaling may be implicated in reward functioning as a potential driver of negative symptoms in schizophrenia. Phosphodiesterase 10A (PDE10A), an enzyme that is highly expressed in the striatum,
Externí odkaz:
https://doaj.org/article/4e96e9575d7248e086f19bdc0d374f88
Autor:
Marco Cecchi, Megumi Adachi, Anthony Basile, Derek Buhl, Heramb Chadchankar, Søren Christensen, Edward Christian, Jim Doherty, KC Fadem, Brandon Farley, Mark Forman, Sokichi Honda, Jason Johannesen, Bruce Kinon, Daniel Klamer, Marino Michael, Christopher Missling, Patricio O'Donnell, Timothy Piser, Corey Puryear, Michael Quirk, Michael Rotte, Connie Sanchez, Daniel Smith, Jason M. Uslaner, Daniel Javitt, Richard SE Keefe, Daniel H. Mathalon, William Potter, David P. Walling, Larry Ereshefsky
Publikováno v:
Schizophrenia Research. 254:178-189
Autor:
John H Krystal, John M Kane, Christoph U Correll, David P Walling, Matthew Leoni, Sridhar Duvvuri, Shrinal Patel, Ih Chang, Philip Iredale, Lillian Frohlich, Stacey Versavel, Pamela Perry, Raymond Sanchez, John Renger
Publikováno v:
The Lancet. 400:2210-2220
Autor:
Marjie L. Hard, Angela Wehr, Lisa von Moltke, Yangchun Du, Sarah Farwick, David P. Walling, John Sonnenberg
Publikováno v:
Therapeutic Advances in Psychopharmacology, Vol 9 (2019)
Background: Aripiprazole lauroxil (AL), a long-acting injectable antipsychotic for the treatment of schizophrenia in adults, can be started with either 21 days of daily oral aripiprazole supplementation or a 1-day initiation regimen consisting of a s
Externí odkaz:
https://doaj.org/article/500584bb4a2a4749bda3c08007f9433d
Autor:
Yihua Zhao, W. Wolfgang Fleischhacker, Stephane Pollentier, Richard S.E. Keefe, Martina Gröschl, Emilio Mantero-Atienza, Jana Podhorna, Michael Desch, Sanjay Hake, David P. Walling, Songqiao Huang, Ronald Brenner, Kazuyuki Nakagome
Publikováno v:
The Lancet Psychiatry. 8:191-201
Summary Background Cognitive impairment associated with schizophrenia predicts poor functional outcomes, but currently no approved pharmacotherapy is available. This study investigated whether the glycine transporter-1 inhibitor BI 425809 improves co
Autor:
David P Walling, Howard A Hassman, Lourdes Anta, Lourdes Ochoa, Ignacio Ayani, Javier Martínez, Ibon Gutierro
Publikováno v:
Drug Design, Development and Therapy. 16:1791-1792
Walling DP, Hassman HA, Anta L, et al. Drug Des Devel Ther. 2021;15:4371–4382. Page 4378, Table 2, PK Parameter column, the text “Cave (ng/nL)” should read “Cave (ng/mL)”. Page 4379, Table 3, PK Parameter column, the text “Cave (ng/nL)”
Autor:
Ibon Gutierro, Lourdes Anta, Ignacio Ayani, David P. Walling, Javier Martínez, Howard A Hassman, Lourdes Ochoa
Publikováno v:
Drug Design, Development and Therapy
David P Walling,1 Howard A Hassman,2 Lourdes Anta,3 Lourdes Ochoa,4 Ignacio Ayani,3 Javier MartÃnez,3 Ibon Gutierro4 1Collaborative Neuroscience Network, LLC Garden Grove, Garden Grove, CA, USA; 2Hassman Research Institute, Berlin, NJ, USA; 3Medic