Zobrazeno 1 - 10
of 559
pro vyhledávání: '"David P Dearnaley"'
Autor:
Chris C Parker, Nicholas D James, Christopher D Brawley, Noel W Clarke, Adnan Ali, Claire L Amos, Gerhardt Attard, Simon Chowdhury, Adrian Cook, William Cross, David P Dearnaley, Hassan Douis, Duncan C Gilbert, Clare Gilson, Silke Gillessen, Alex Hoyle, Rob J Jones, Ruth E Langley, Zafar I Malik, Malcolm D Mason, David Matheson, Robin Millman, Mary Rauchenberger, Hannah Rush, J Martin Russell, Hannah Sweeney, Amit Bahl, Alison Birtle, Lisa Capaldi, Omar Din, Daniel Ford, Joanna Gale, Ann Henry, Peter Hoskin, Mohammed Kagzi, Anna Lydon, Joe M O'Sullivan, Sangeeta A Paisey, Omi Parikh, Delia Pudney, Vijay Ramani, Peter Robson, Narayanan Nair Srihari, Jacob Tanguay, Mahesh K B Parmar, Matthew R Sydes, STAMPEDE Trial Collaborative Group
Publikováno v:
PLoS Medicine, Vol 19, Iss 6, p e1003998 (2022)
BackgroundSTAMPEDE has previously reported that radiotherapy (RT) to the prostate improved overall survival (OS) for patients with newly diagnosed prostate cancer with low metastatic burden, but not those with high-burden disease. In this final analy
Externí odkaz:
https://doaj.org/article/6362f7c1f7f944ef83cd0276f5fe8143
Autor:
Caroline S Clarke, Rachael M Hunter, Andrea Gabrio, Christopher D Brawley, Fiona C Ingleby, David P Dearnaley, David Matheson, Gerhardt Attard, Hannah L Rush, Rob J Jones, William Cross, Chris Parker, J Martin Russell, Robin Millman, Silke Gillessen, Zafar Malik, Jason F Lester, James Wylie, Noel W Clarke, Mahesh K B Parmar, Matthew R Sydes, Nicholas D James
Publikováno v:
PLoS ONE, Vol 17, Iss 6, p e0269192 (2022)
Adding abiraterone acetate (AA) plus prednisolone (P) to standard of care (SOC) improves survival in newly diagnosed advanced prostate cancer (PC) patients starting hormone therapy. Our objective was to determine the value for money to the English Na
Externí odkaz:
https://doaj.org/article/6a675b239ade470a88b2ee43883ed235
Autor:
Agnieszka Lemanska, Rachel C Byford, Clare Cruickshank, David P Dearnaley, Filipa Ferreira, Clare Griffin, Emma Hall, William Hinton, Simon de Lusignan, Julian Sherlock, Keeley Tomkinson, Jeremy van Vlymen, Sara Faithfull
Publikováno v:
International Journal of Population Data Science, Vol 3, Iss 4 (2018)
Introduction The aim is to investigate the effect of cardiovascular and diabetes comorbidities on radiotherapy-related side-effects in prostate cancer. Previous research suggests that comorbidities increase the risk of side-effects, but some cardiova
Externí odkaz:
https://doaj.org/article/4eff547874a44936b56972df7754cd54
Autor:
Gerhardt Attard, Laura Murphy, Noel W Clarke, Ashwin Sachdeva, Craig Jones, Alex Hoyle, William Cross, Robert J Jones, Christopher C Parker, Silke Gillessen, Adrian Cook, Chris Brawley, Clare Gilson, Hannah Rush, Hoda Abdel-Aty, Claire L Amos, Claire Murphy, Simon Chowdhury, Zafar Malik, J Martin Russell, Nazia Parkar, Cheryl Pugh, Carlos Diaz-Montana, Carmel Pezaro, Warren Grant, Helen Saxby, Ian Pedley, Joe M O'Sullivan, Alison Birtle, Joanna Gale, Narayanan Srihari, Carys Thomas, Jacob Tanguay, John Wagstaff, Prantik Das, Emma Gray, Mymoona Alzouebi, Omi Parikh, Angus Robinson, Amir H Montazeri, James Wylie, Anjali Zarkar, Richard Cathomas, Michael D Brown, Yatin Jain, David P Dearnaley, Malcolm D Mason, Duncan Gilbert, Ruth E Langley, Robin Millman, David Matheson, Matthew R Sydes, Louise C Brown, Mahesh K B Parmar, Nicholas D James, Elin Jones, Katherine Hyde, Hilary Glen, Sarah Needleman, Ursula McGovern, Denise Sheehan, Sangeeta Paisey, Richard Shaffer, Mark Beresford, Emilio Porfiri, David Fackrell, Ling Lee, Thiagarajan Sreenivasan, Sue Brock, Simon Brown, Amit Bahl, Mike Smith-Howell, Cathryn Woodward, Mau-Don Phan, Danish Mazhar, Krishna Narahari, Fiona Douglas, Anil Kumar, Abdel Hamid, Azman Ibrahim, Dakshinamoorthy Muthukumar, Matthew Simms, Jane Worlding, Anna Tran, Mohammed Kagzi, Virgil Sivoglo, Benjamin Masters, Pek Keng-Koh, Caroline Manetta, Duncan McLaren, Nishi Gupta, Stergios Boussios, Henry Taylor, John Graham, Carla Perna, Lucinda Melcher, Ami Sabharwal, Uschi Hofmann, Robert Dealey, Neil McPhail, Robert Brierly, Lisa Capaldi, Norma Sidek, Peter Whelan, Peter Robson, Alison Falconer, Sarah Rudman, Sindu Vivekanandan, Vinod Mullessey, Maria Vilarino-Varela, Vincent Khoo, Karen Tipples, Mehran Afshar, Patryk Brulinski, Vijay Sangar, Clive Peedell, Ashraf Azzabi, Peter Hoskin, Viwod Mullassery, Santhanam Sundar, Yakhub Khan, Ruth Conroy, Andrew Protheroe, Judith Carser, Paul Rogers, Kathryn Tarver, Stephanie Gibbs, Mohammad Muneeb Khan, Mohan Hingorani, Simon Crabb, Manal Alameddine, Neeraj Bhalla, Robert Hughes, John Logue, Darren Leaning, Salil Vengalil, Daniel Ford, Georgina Walker, Ahmed Shaheen, Omar Khan, Andrew Chan, Imtiaz Ahmed, Serena Hilman, Ian Sayers, Ashok Nikapota, David Bloomfield, Tim Porter, Joji Joseph, Cyrill Rentsch, Ricardo Pereira Mestre, Enrico Roggero, Jörg Beyer, Markus Borner, Raeto Strebel, Dominik Berthold, Daniel Engeler, Hubert John, Razvan Popescu, Donat Durr
Publikováno v:
STAMPEDE investigators, Attard, G, Murphy, L, Clarke, N W, Sachdeva, A, Jones, C, Hoyle, A, Cross, W, Jones, R J, Parker, C C, Gillessen, S, Cook, A, Brawley, C, Gilson, C, Rush, H, Abdel-Aty, H, Amos, C L, Murphy, C, Chowdhury, S, Malik, Z, Russell, J M, Parkar, N, Pugh, C, Diaz-Montana, C, Pezaro, C, Grant, W, Saxby, H, Pedley, I, O'Sullivan, J M, Birtle, A, Gale, J, Srihari, N, Thomas, C, Tanguay, J, Wagstaff, J, Das, P, Gray, E, Alzouebi, M, Parikh, O, Robinson, A, Montazeri, A H, Wylie, J, Zarkar, A, Cathomas, R, Brown, M D, Jain, Y, Dearnaley, D P, Mason, M D, Gilbert, D, Langley, R E & Millman, R 2023, ' Abiraterone acetate plus prednisolone with or without enzalutamide for patients with metastatic prostate cancer starting androgen deprivation therapy: final results from two randomised phase 3 trials of the STAMPEDE platform protocol ', Lancet Oncology, vol. 24, no. 5, pp. 443-456 . https://doi.org/10.1016/S1470-2045(23)00148-1
Attard, G, Murphy, L, Clarke, N W, Sachdeva, A, Jones, C, Hoyle, A, Cross, W, Jones, R J, Parker, C C, Gillessen, S, Cook, A, Brawley, C, Gilson, C, Rush, H, Abdel-Aty, H, Amos, C L, Murphy, C, Chowdhury, S, Malik, Z, Russell, J M, Parkar, N, Pugh, C, Diaz-Montana, C, Pezaro, C, Grant, W, Saxby, H, Pedley, I, O'Sullivan, J M, Birtle, A, Gale, J, Srihari, N, Thomas, C, Tanguay, J, Wagstaff, J, Das, P, Gray, E, Alzouebi, M, Parikh, O, Robinson, A, Montazeri, A H, Wylie, J, Zarkar, A, Cathomas, R, Brown, M D, Jain, Y, Dearnaley, D P, Mason, M D, Gilbert, D, Langley, R E & Millman, R 2023, ' Abiraterone acetate plus prednisolone with or without enzalutamide for patients with metastatic prostate cancer starting androgen deprivation therapy : final results from two randomised phase 3 trials of the STAMPEDE platform protocol ', The Lancet. Oncology, vol. 24, no. 5, pp. 443-456 . https://doi.org/10.1016/S1470-2045(23)00148-1
Attard, G, Murphy, L, Clarke, N W, Sachdeva, A, Jones, C, Hoyle, A, Cross, W, Jones, R J, Parker, C C, Gillessen, S, Cook, A, Brawley, C, Gilson, C, Rush, H, Abdel-Aty, H, Amos, C L, Murphy, C, Chowdhury, S, Malik, Z, Russell, J M, Parkar, N, Pugh, C, Diaz-Montana, C, Pezaro, C, Grant, W, Saxby, H, Pedley, I, O'Sullivan, J M, Birtle, A, Gale, J, Srihari, N, Thomas, C, Tanguay, J, Wagstaff, J, Das, P, Gray, E, Alzouebi, M, Parikh, O, Robinson, A, Montazeri, A H, Wylie, J, Zarkar, A, Cathomas, R, Brown, M D, Jain, Y, Dearnaley, D P, Mason, M D, Gilbert, D, Langley, R E & Millman, R 2023, ' Abiraterone acetate plus prednisolone with or without enzalutamide for patients with metastatic prostate cancer starting androgen deprivation therapy : final results from two randomised phase 3 trials of the STAMPEDE platform protocol ', The Lancet. Oncology, vol. 24, no. 5, pp. 443-456 . https://doi.org/10.1016/S1470-2045(23)00148-1
Background: Abiraterone acetate plus prednisolone (herein referred to as abiraterone) or enzalutamide added at the start of androgen deprivation therapy improves outcomes for patients with metastatic prostate cancer. Here, we aimed to evaluate long-t
Autor:
Douglas H. Brand, Sarah C. Brüningk, Anna Wilkins, Olivia Naismith, Annie Gao, Isabel Syndikus, David P. Dearnaley, Nicholas van As, Emma Hall, Sarah Gulliford, Alison C. Tree
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 115:327-336
Autor:
Ting Martin Ma, Fang-I Chu, Howard Sandler, Felix Y. Feng, Jason A. Efstathiou, Christopher U. Jones, Mack Roach, Seth A. Rosenthal, Thomas Pisansky, Jeff M. Michalski, Michel Bolla, Theo M. de Reijke, Philippe Maingon, Anouk Neven, James Denham, Allison Steigler, David Joseph, Abdenour Nabid, Luis Souhami, Nathalie Carrier, Luca Incrocci, Wilma Heemsbergen, Floris J. Pos, Matthew R. Sydes, David P. Dearnaley, Alison C. Tree, Isabel Syndikus, Emma Hall, Clare Cruickshank, Shawn Malone, Soumyajit Roy, Yilun Sun, Nicholas G. Zaorsky, Nicholas G. Nickols, Robert E. Reiter, Matthew B. Rettig, Michael L. Steinberg, Vishruth K. Reddy, Michael Xiang, Tahmineh Romero, Daniel E. Spratt, Amar U. Kishan
Publikováno v:
European urology. 82(5):487-498
Context: The prognostic importance of local failure after definitive radiotherapy (RT) in National Comprehensive Cancer Network intermediate- and high-risk prostate cancer (PCa) patients remains unclear. Objective: To evaluate the prognostic impact o
Autor:
Amar U. Kishan, Xiaoyan Wang, Yilun Sun, Tahmineh Romero, Jeff M. Michalski, Ting Martin Ma, Felix Y. Feng, Howard M. Sandler, Michel Bolla, Philippe Maingon, Theo De Reijke, Anouk Neven, Allison Steigler, James W. Denham, David Joseph, Abdenour Nabid, Nathalie Carrier, Luis Souhami, Matt R. Sydes, David P. Dearnaley, Isabel Syndikus, Alison C. Tree, Luca Incrocci, Wilma D. Heemsbergen, Floris J. Pos, Almudena Zapatero, Jason A. Efstathiou, Araceli Guerrero, Ana Alvarez, Carmen Gonzalez San-Segundo, Xavier Maldonado, Michael Xiang, Matthew B. Rettig, Robert E. Reiter, Nicholas G. Zaorsky, Wee Loon Ong, Robert T. Dess, Michael L. Steinberg, Nicholas G. Nickols, Soumyajit Roy, Jorge A. Garcia, Daniel E. Spratt
Publikováno v:
European Urology, 82(1), 106-114. Elsevier
European urology, 82(1), 106-114. Elsevier
European urology, 82(1), 106-114. Elsevier
Background: The relative benefits of radiotherapy (RT) dose escalation and the addition of short-term or long-term androgen deprivation therapy (STADT or LTADT) in the treatment of prostate cancer are unknown. Objective: To perform a network meta-ana
Autor:
David P. Dearnaley, Julian R. Marchesi, Sarah L. Gulliford, Jia Li, Sharon M. Gowan, Lesley Truelove, Kabir Mohammed, H. Jervoise N. Andreyev, Miguel Reis Ferreira
Supplementary materials document.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86742142546f4b504ac75679ad570883
https://doi.org/10.1158/1078-0432.22471448.v1
https://doi.org/10.1158/1078-0432.22471448.v1
Autor:
David P. Dearnaley, Julian R. Marchesi, Sarah L. Gulliford, Jia Li, Sharon M. Gowan, Lesley Truelove, Kabir Mohammed, H. Jervoise N. Andreyev, Miguel Reis Ferreira
Data used in study analyses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a0833140cde5196658f0ab34311b593
https://doi.org/10.1158/1078-0432.22471451.v1
https://doi.org/10.1158/1078-0432.22471451.v1
Autor:
David P. Dearnaley, Julian R. Marchesi, Sarah L. Gulliford, Jia Li, Sharon M. Gowan, Lesley Truelove, Kabir Mohammed, H. Jervoise N. Andreyev, Miguel Reis Ferreira
Purpose:Radiotherapy is important in managing pelvic cancers. However, radiation enteropathy may occur and can be dose limiting. The gut microbiota may contribute to the pathogenesis of radiation enteropathy. We hypothesized that the microbiome diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d3f41386566db63bdb39086af490cd5
https://doi.org/10.1158/1078-0432.c.6527900
https://doi.org/10.1158/1078-0432.c.6527900