Zobrazeno 1 - 10
of 65
pro vyhledávání: '"David P Braun"'
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0206313 (2018)
All Canadian lake sturgeon (Acipenser fulvescens) populations are listed under the Committee on the Status of Endangered Wildlife in Canada (COSEWIC) due to their complex life history, loss of habitat and negative interactions with anthropomorphic ac
Externí odkaz:
https://doaj.org/article/d61ccd13496343578f3087767a49dfcd
Autor:
Amanda McGrosky, Zane S. Swanson, Rebecca Rimbach, Hilary Bethancourt, Emmanuel Ndiema, Rosemary Nzunza, David R. Braun, Asher Y. Rosinger, Herman Pontzer
Publikováno v:
Annals of Human Biology, Vol 51, Iss 1 (2024)
AbstractBackground Pastoralists live in challenging environments, which may be accompanied by unique activity, energy, and water requirements.Aim Few studies have examined whether the demands of pastoralism contribute to differences in total energy e
Externí odkaz:
https://doaj.org/article/08ee21a2249343a288628a5627cf1058
Autor:
Hilaree N. Frazier, David J. Braun, Caleb S. Bailey, Meggie J. Coleman, Verda A. Davis, Stephen R. Dundon, Christopher J. McLouth, Hana C. Muzyk, David K. Powell, Colin B. Rogers, Saktimayee M. Roy, Linda J. Van Eldik
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 40, Iss , Pp 100826- (2024)
Background: Inhibition of p38 alpha mitogen activated protein kinase (p38α) has shown great promise as a treatment for Alzheimer's disease (AD) in preclinical tests. However, previous preclinical studies were performed in “pure” models of AD pat
Externí odkaz:
https://doaj.org/article/88b7fccff3084851bc566ef4cb37065a
PAK4-targeted PROTACs in clear cell renal cell carcinoma: a two-for-one targeted and immune therapy?
Publikováno v:
EBioMedicine, Vol 105, Iss , Pp 105218- (2024)
Externí odkaz:
https://doaj.org/article/293403738f37475c870d70d649eea09a
Autor:
Talal El Zarif, Karl Semaan, Marc Eid, Ji-Heui Seo, Simon Garinet, Matthew P. Davidsohn, Pranshu Sahgal, Brad Fortunato, John Canniff, Amin H. Nassar, Sarah Abou Alaiwi, Ziad Bakouny, Gitanjali Lakshminarayanan, Hunter Savignano, Kevin Lyons, Sayed Matar, Atef Ali, Eddy Saad, Renee Maria Saliby, Paulo Cordeiro, Ziwei Zhang, Nourhan El Ahmar, Yasmin Nabil Laimon, Chris Labaki, Valisha Shah, Dory Freeman, Jillian O’Toole, Gwo-Shu Mary Lee, Justin Hwang, Mark Pomerantz, Sabina Signoretti, Eliezer M. Van Allen, Wanling Xie, Jacob E. Berchuck, Srinivas R. Viswanathan, David A. Braun, Toni K. Choueiri, Matthew L. Freedman, Sylvan C. Baca
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114350- (2024)
Summary: Renal cell carcinoma with sarcomatoid differentiation (sRCC) is associated with poor survival and a heightened response to immune checkpoint inhibitors (ICIs). Two major barriers to improving outcomes for sRCC are the limited understanding o
Externí odkaz:
https://doaj.org/article/a9e18e74ab10487c9c8418746dfe9c2a
Autor:
Stella G. Mosher, Mitchell J. Power, Lynne J. Quick, Torsten Haberzettl, Thomas Kasper, Kelly L. Kirsten, David R. Braun, J. Tyler Faith
Publikováno v:
Quaternary Science Advances, Vol 14, Iss , Pp 100194- (2024)
Fire is central to the Cape Floristic Region's highly biodiverse and disturbance-adapted Fynbos Biome. However, prehistoric fire regimes, their ecological consequences, and their relationships with large-scale climate drivers and human activities rem
Externí odkaz:
https://doaj.org/article/6acaf19ffeab44afa05c5e9d0af6f5c0
Autor:
Yufei Wang, Jae-Won Cho, Gabriella Kastrunes, Alicia Buck, Cecile Razimbaud, Aedin C. Culhane, Jiusong Sun, David A. Braun, Toni K. Choueiri, Catherine J. Wu, Kristen Jones, Quang-De Nguyen, Zhu Zhu, Kevin Wei, Quan Zhu, Sabina Signoretti, Gordon J. Freeman, Martin Hemberg, Wayne A. Marasco
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108879- (2024)
Summary: One of the major barriers that have restricted successful use of chimeric antigen receptor (CAR) T cells in the treatment of solid tumors is an unfavorable tumor microenvironment (TME). We engineered CAR-T cells targeting carbonic anhydrase
Externí odkaz:
https://doaj.org/article/0c2301842fd04b6197a7bca08f019c78
Autor:
Hilary J Bethancourt, Zane S Swanson, Rosemary Nzunza, Sera L Young, Luke Lomeiku, Matthew J Douglass, David R Braun, Emmanuel K Ndiema, Herman Pontzer, Asher Yoel Rosinger
Publikováno v:
Public Health Nutrition, Vol 26, Pp 693-703 (2023)
Abstract Objective: Water plays a critical role in the production of food and preparation of nutritious meals, yet few studies have examined the relationship between water and food insecurity. The primary objective of this study, therefore, was to e
Externí odkaz:
https://doaj.org/article/2c13f050af094d07be73819b2d768c1c
Autor:
Sidharth Sen, Shannon K. King, Tyler McCubbin, Laura A. Greeley, Rachel A. Mertz, Cheyenne Becker, Nicole Niehues, Shuai Zeng, Jonathan T. Stemmle, Scott C. Peck, Melvin J. Oliver, Felix B. Fritschi, David M. Braun, Robert E. Sharp, Trupti Joshi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Certain cultivars of maize show increased tolerance to water deficit conditions by maintenance of root growth. To better understand the molecular mechanisms related to this adaptation, nodal root growth zone samples were collected from the r
Externí odkaz:
https://doaj.org/article/77d62a71daa4427f988f204d550cff00
Autor:
Amin H. Nassar, Sarah Abou Alaiwi, Sylvan C. Baca, Elio Adib, Rosario I. Corona, Ji-Heui Seo, Marcos A. S. Fonseca, Sandor Spisak, Talal El Zarif, Viktoria Tisza, David A. Braun, Heng Du, Monica He, Abdallah Flaifel, Michel Alchoueiry, Thomas Denize, Sayed G. Matar, Andres Acosta, Sachet Shukla, Yue Hou, John Steinharter, Gabrielle Bouchard, Jacob E. Berchuck, Edward O’Connor, Connor Bell, Pier Vitale Nuzzo, Gwo-Shu Mary Lee, Sabina Signoretti, Michelle S. Hirsch, Mark Pomerantz, Elizabeth Henske, Alexander Gusev, Kate Lawrenson, Toni K. Choueiri, David J. Kwiatkowski, Matthew L. Freedman
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
The epigenomic landscape of renal cell carcinoma (RCC) remains to be explored. Here, integrative epigenomic analysis of primary human RCC samples and RCC GWAS risk SNPs identifies transcription-factor specific subtypes and enrichment of risk variants
Externí odkaz:
https://doaj.org/article/5c45bbe4ef1e4b0b9d9d760011ce2040