Zobrazeno 1 - 10
of 92
pro vyhledávání: '"David P Boyle"'
Autor:
Garrett Dunlap, Aaron Wagner, Nida Meednu, Ruoqiao Wang, Fan Zhang, Jabea Cyril Ekabe, Anna Helena Jonsson, Kevin Wei, Saori Sakaue, Aparna Nathan, Accelerating Medicines Partnership Program: Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Network, Vivian P. Bykerk, Laura T. Donlin, Susan M. Goodman, Gary S. Firestein, David L. Boyle, V. Michael Holers, Larry W. Moreland, Darren Tabechian, Costantino Pitzalis, Andrew Filer, Soumya Raychaudhuri, Michael B. Brenner, Juilee Thakar, Andrew McDavid, Deepak A. Rao, Jennifer H. Anolik
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Rheumatoid arthritis (RA) is an autoimmune disease involving antigen-specific T and B cells. Here, we perform single-cell RNA and repertoire sequencing on paired synovial tissue and blood samples from 12 seropositive RA patients. We identify
Externí odkaz:
https://doaj.org/article/b76b85a9921847d4919133eeb47ed023
Autor:
Eddie A. James, V. Michael Holers, Radhika Iyer, E. Barton Prideaux, Navin L. Rao, Cliff Rims, Virginia S. Muir, Sylvia E. Posso, Michelle S. Bloom, Amin Zia, Serra E. Elliott, Julia Z. Adamska, Rizi Ai, R. Camille Brewer, Jennifer A. Seifert, LauraKay Moss, Saman Barzideh, M. Kristen Demoruelle, Christopher C. Striebich, Yuko Okamoto, Enkhtsogt Sainbayar, Alexandra A. Crook, Ryan A. Peterson, Lauren A. Vanderlinden, Wei Wang, David L. Boyle, William H. Robinson, Jane H. Buckner, Gary S. Firestein, Kevin D. Deane
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Molecular markers of autoimmunity, such as antibodies to citrullinated protein antigens (ACPA), are detectable prior to inflammatory arthritis (IA) in rheumatoid arthritis (RA) and may define a state that is ‘at-risk’ for future RA. Here
Externí odkaz:
https://doaj.org/article/a3d2e67207bd4673ae2092ef39c22e10
Autor:
Hyeonjeong Lee, Camilla R L Machado, Deepa Hammaker, Eunice Choi, Edward B Prideaux, Wei Wang, David L Boyle, Gary S Firestein
Publikováno v:
PLoS ONE, Vol 19, Iss 6, p e0304530 (2024)
Rheumatoid arthritis (RA) is a systemic immune-mediated disease characterized by joint inflammation and destruction. The disease typically affects small joints in the hands and feet, later progressing to involve larger joints such as the knees, shoul
Externí odkaz:
https://doaj.org/article/2b85a7c05bcd4e318c6f0ff23d6ac2bb
Autor:
Sarah E. Philo, Nicolette A. Zhou, Lorraine M. Lillis, Venkata Raghava, Dilip Abraham, Vinoth Kumar, Nirmal Kumar, Jonathan Rigby, Joanna Ciol Harrison, Christine S. Fagnant-Sperati, Alexandra L. Kossik, Angelo Q. W. Ong, Rachael Swanstrom, Elisabeth Burnor, Bethel Demeke, Nicola K. Beck, Jeffry H. Shirai, Stephen J. Libby, David S. Boyle, Nicholas Feasey, Gagandeep Kang, John Scott Meschke
Publikováno v:
PLoS ONE, Vol 19, Iss 5 (2024)
Externí odkaz:
https://doaj.org/article/3cb0d247f348490680866a57895e2233
Autor:
Wenxiao Huang, Yusheng Ye, Hao Chen, Rafael A. Vilá, Andrew Xiang, Hongxia Wang, Fang Liu, Zhiao Yu, Jinwei Xu, Zewen Zhang, Rong Xu, Yecun Wu, Lien-Yang Chou, Hansen Wang, Junwei Xu, David Tomas Boyle, Yuzhang Li, Yi Cui
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Fast-charging is highly desired for lithium-ion batteries but is hindered by potential hazardous lithium plating and the associated parasitic reactions. Here, the authors report a nondestructive differential pressure sensing method for early detectio
Externí odkaz:
https://doaj.org/article/236e87491e8149d6a54b20499c4c428e
Autor:
Richard I. Ainsworth, Deepa Hammaker, Gyrid Nygaard, Cecilia Ansalone, Camilla Machado, Kai Zhang, Lina Zheng, Lucy Carrillo, Andre Wildberg, Amanda Kuhs, Mattias N. D. Svensson, David L. Boyle, Gary S. Firestein, Wei Wang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Fibroblast-like synoviocytes (FLS) are used as a model of rheumatoid arthritis synoviocytes, although cell lines derived from individual patients can have heterogeneous biology. Here the authors use a Taiji computational approach to analyze gene expr
Externí odkaz:
https://doaj.org/article/c8daa11cab114d9a8d1dd398242e20b7
Autor:
Allison Golden, Jason L. Cantera, Lorraine Lillis, Thanh T. Phan, Hannah Slater, Edwin J. Webb, Roger B. Peck, David S. Boyle, Gonzalo J. Domingo
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Rapid diagnostic tests (RDTs) that detect antigen indicative of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection can help in making quick health care decisions and regularly monitoring groups at risk of infection. With
Externí odkaz:
https://doaj.org/article/2c24fd13d028408f9d9a7fb64cb7b608
Autor:
Solomon T. Oyakhire, Wenbo Zhang, Andrew Shin, Rong Xu, David T. Boyle, Zhiao Yu, Yusheng Ye, Yufei Yang, James A. Raiford, William Huang, Joel R. Schneider, Yi Cui, Stacey F. Bent
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
The deployment of lithium metal batteries is forestalled by poor control over the deposition morphology of lithium. Here, the authors discover that high electrical resistance can be leveraged for controlling lithium morphology and enabling high-perfo
Externí odkaz:
https://doaj.org/article/409096afb97d46a6b96684bd112a3858
Autor:
Michalina A. Montaño, Meagan J. Bemer, Kate B. Heller, Allison Meisner, Zarna Marfatia, Elena A. Rechkina, Leah R. Padgett, Charlotte L. Ahls, Douglas Rains, Linhui Hao, Tien-Ying Hsiang, Gerard A. Cangelosi, Alexander L. Greninger, Jason L. Cantera, Allison Golden, Roger B. Peck, David S. Boyle, Michael Gale, Jr, Paul K. Drain
Publikováno v:
International Journal of Infectious Diseases, Vol 117, Iss , Pp 287-294 (2022)
Objectives: This study assesses and compares the performance of different swab types and specimen collection sites for SARS-CoV-2 testing, to reference standard real-time reverse transcriptase-polymerase chain reaction (RT-PCR) and viral culture. Met
Externí odkaz:
https://doaj.org/article/eff16240d3474357915a98a71b334683
Autor:
Cecilia Ansalone, Richard I. Ainsworth, Gyrid Nygaard, Rizi Ai, Edward B. Prideaux, Deepa Hammaker, Narayanan B. Perumal, Ken Weichert, Frances Tung, Lalitha Kodandapani, J. Michael Sauder, Elisabeth C. Mertsching, Robert J. Benschop, David L. Boyle, Wei Wang, Gary S. Firestein
Publikováno v:
ACR Open Rheumatology, Vol 4, Iss 4, Pp 288-299 (2022)
Objective Fibroblast‐like synoviocytes (FLS) play a pivotal role in rheumatoid arthritis (RA) by contributing to synovial inflammation and progressive joint damage. An imprinted epigenetic state is associated with the FLS aggressive phenotype. We i
Externí odkaz:
https://doaj.org/article/7bf9364f9ed048b68c6e9061d4e747da