Zobrazeno 1 - 10
of 87
pro vyhledávání: '"David Onions"'
Autor:
Kevin J. Kayser, Trissa Borgschulte, Henry George, Daniel Miller, Joaquina Mascarenhas, Lisa R. Burger, Jason Tuter, Audrey Chang, David Onions, Ademola Kassim, Nikolay Korokhov, David J. Pintel
Publikováno v:
Biotechnology and Bioengineering. 114:576-588
Contamination by the parvovirus minute virus of mice (MVM) remains a challenge in Chinese hamster ovary (CHO) biopharmaceutical production processes. Although infrequent, infection of a bioreactor can be catastrophic for a manufacturer, can impact pa
Autor:
Audrey Chang, Katherine Achtien, Colette Cote, Lakshmi Viswanathan, Yitao Tang, David Razafsky, Trissa Borgschulte, Alexei I. Slesarev, David Onions
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
The robust detection of structural variants in mammalian genomes remains a challenge. It is particularly difficult in the case of genetically unstable Chinese hamster ovary (CHO) cell lines with only draft genome assemblies available. We explore the
Autor:
Joaquina X, Mascarenhas, Nikolay, Korokhov, Lisa, Burger, Ademola, Kassim, Jason, Tuter, Daniel, Miller, Trissa, Borgschulte, Henry J, George, Audrey, Chang, David J, Pintel, David, Onions, Kevin J, Kayser
Publikováno v:
Biotechnology and bioengineering. 114(3)
Contamination by the parvovirus minute virus of mice (MVM) remains a challenge in Chinese hamster ovary (CHO) biopharmaceutical production processes. Although infrequent, infection of a bioreactor can be catastrophic for a manufacturer, can impact pa
Autor:
David Onions
Publikováno v:
PDA Journal of Pharmaceutical Science and Technology. 65:654-659
CONFERENCE PROCEEDING Proceedings of the PDA/FDA Adventitious Viruses in Biologics: Detection and Mitigation Strategies Workshop in Bethesda, MD, USA; December 1-3, 2010 Guest Editors: Arifa Khan (Bethesda, MD), Patricia Hughes (Bethesda, MD) and Mic
Autor:
J L Kolman, Frances M. D. Gulland, David Onions, Eric Delwart, Chunlin Wang, Tongling Shan, Colette Cote, Linlin Li
Publikováno v:
Journal of Virology. 85:9909-9917
California sea lions are one of the major marine mammal species along the Pacific coast of North America. Sea lions are susceptible to a wide variety of viruses, some of which can be transmitted to or from terrestrial mammals. Using an unbiased viral
Ensuring the safety of vaccine cell substrates by massively parallel sequencing of the transcriptome
Publikováno v:
Vaccine. 29:7117-7121
Massively parallel, deep, sequencing of the transcriptome coupled with algorithmic analysis to identify adventitious agents (MP-Seq™) is an important adjunct in ensuring the safety of cells used in vaccine production. Such cells may harbour novel v
Autor:
David Argyle, D. Bain, H. van Zuilekom, Elizabeth L. McMonagle, Samantha Taylor, Nicolette C Scholtes, Virgil E.J.C. Schijns, David Onions, C. A. Hopkins, Lesley Nicolson, N. A. Logan, L. Sanders, L. J. Keanie
Publikováno v:
Equine Veterinary Journal. 33:693-698
Interleukin-12 (IL-12) is a key cytokine in the development of cell-mediated immune responses. Bioactive IL-12 is a heterodimeric cytokine composed of disulphide linked p35 and p40 subunits. The aim of this study was to verify biologically activity o
Publikováno v:
Vaccine Analysis: Strategies, Principles, and Control ISBN: 9783662450239
The introduction of deep sequencing or massively parallel sequencing (MPS) technologies has resulted in a qualitative, as well as a quantitative, change in the information that can be gained from nucleic acid sequencing.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b396e2c08dbc8e443a72140b8df18c52
https://doi.org/10.1007/978-3-662-45024-6_11
https://doi.org/10.1007/978-3-662-45024-6_11
Autor:
David Argyle, Lesley Nicolson, D. Bain, Samantha Taylor, Elizabeth L. McMonagle, Linda Hanlon, David Onions, Lucy O'Donovan, Mathew C Golder, Oswald Jarrett, Michael McDonald, Angela M. Pacitti
Publikováno v:
Vaccine
DNA vaccination using vectors expressing the gag/pol and env genes of feline leukaemia virus (FeLV) and plasmids encoding feline interleukin-12 (IL-12) and IL-18 completely protected cats from viraemia following challenge [Hanlon L, Argyle D, Bain D,
Autor:
Henry George, Trissa Borgschulte, Kevin J. Kayser, Ademola Kassim, Audrey Chang, Joaquina Mascarenhas, David Onions, Nikolay Korokhov
Publikováno v:
Genetic Engineering & Biotechnology News. 36:34-35