Výsledky vyhledávání - "David Okhotin"

Durable Chronic Low Back Pain Reductions to 24-Months Post-Treatment for An Accessible, 8-Week, In-Home Behavioral Skills-Based Virtual Reality Program: A Randomized Controlled Trial

Autor: Todd Maddox, Charisse Sparks, Liesl Oldstone, Roselani Maddox, Kelsey Ffrench, Heidy Garcia, Parthasarathy Krishnamurthy, David Okhotin, Laura M Garcia, Brandon J Birckhead, Josh Sackman, Ian Mackey, Robert Louis, Vafi Salmasi, Alexis Oyao, Beth D Darnall

Publikováno v: Pain Medicine.

Trial Registration Information ClinicalTrials.gov NCT04415177; https://clinicaltrials.gov/ct2/show/NCT04415177 International Registered Report Identifier (IRRID) RR2-10.2196/25291

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::05218c0e682203baf5bad5fd6cae2146
https://doi.org/10.1093/pm/pnad070

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In-home virtual reality program for chronic low back pain: durability of a randomized, placebo-controlled clinical trial to 18 months post-treatment

Autor: Todd Maddox, Heidy Garcia, Kelsey Ffrench, Roselani Maddox, Laura Garcia, Parthasarathy Krishnamurthy, David Okhotin, Charisse Sparks, Liesl Oldstone, Brandon Birckhead, Josh Sackman, Ian Mackey, Robert Louis, Vafi Salmasi, Alexis Oyao, Beth D Darnall

Publikováno v: Regional Anesthesia & Pain Medicine. :rapm-2022

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f2f667b9428d3ea1ef0f981a6fbab0f
https://doi.org/10.1136/rapm-2022-104093

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Decreased serum glucose and glycosylated hemoglobin levels in patients with Chuvash polycythemia: a role for HIF in glucose metabolism

Publikováno v: Journal of Molecular Medicine. 91:59-67

In Chuvash polycythemia, a homozygous 598CT mutation in the von Hippel-Lindau gene (VHL) leads to an R200W substitution in VHL protein, impaired degradation of α-subunits of hypoxia-inducible factor (HIF)-1 and HIF-2, and augmented hypoxic responses

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9032349eec4a9c681977c10d5f7b2d4c
https://doi.org/10.1007/s00109-012-0961-5

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Increased size of solid organs in patients with Chuvash polycythemia and in mice with altered expression of HIF-1α and HIF-2α

Autor: Daniel J. Okhotin, Josef T. Prchal, Galina Y. Miasnikova, Donghoon Yoon, Yong Gu Lee, Yulia Okhotina, Gregg L. Semenza, Bum Jun Kim, David Okhotin, Adelina I. Sergueeva, Alexei Maslow, Victor R. Gordeuk, Lydia A. Polyakova

Publikováno v: Journal of Molecular Medicine. 88:523-530

Chuvash polycythemia, the first hereditary disease associated with dysregulated oxygen-sensing to be recognized, is characterized by a homozygous germ-line loss-of-function mutation of the VHL gene (VHL(R200W)) resulting in elevated hypoxia inducible

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2efbb7dcbd048f5514e90f2120d0e38
https://doi.org/10.1007/s00109-010-0599-0

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Increased Ratios of Internal Organ Volume to Body Mass in Chuvash Polycythemia and HIF-2α Repression of p21Cip Expression through C-MYC

Autor: Alexei Maslow, Galina Y. Miasnikova, Daniel J. Okhotin, Victor R. Gordeuk, Adelina I. Sergueeva, David Okhotin, Gregg L. Semenza, Donghoon Yoon, Josef T. Prchal, Yong Gu Lee, Lydia A. Polyakova, Bum Jun Kim, Yulia Okhotina

Publikováno v: Blood. 114:5039-5039

Abstract 5039 Chuvash polycythemia, the first hereditary disease associated with dysregulated oxygen sensing, is characterized by homozygous germ-line loss-of-function mutation of VHL (598C>T) resulting in elevated hypoxia inducible factor (HIF)-1 an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b5bdea2af06032fdf30f26758d00298c
https://doi.org/10.1182/blood.v114.22.5039.5039

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