Zobrazeno 1 - 10
of 33
pro vyhledávání: '"David Oehme"'
Publikováno v:
Stem Cells International, Vol 2015 (2015)
Low back pain and degenerative disc disease are a significant cause of pain and disability worldwide. Advances in regenerative medicine and cell-based therapies, particularly the transplantation of mesenchymal stem cells and intervertebral disc chond
Externí odkaz:
https://doaj.org/article/0aadd0275d084daf828eb3d7867b8c55
Autor:
David Oehme, Tony Goldschlager, Jeffrey Rosenfeld, Andrew Danks, Peter Ghosh, Anne Gibbon, Graham Jenkin
Publikováno v:
The Scientific World Journal, Vol 2012 (2012)
The sheep is becoming increasingly used as a large animal model for preclinical spine surgery studies. Access to the ovine lumbar intervertebral discs has traditionally been via an anterior or anterolateral approach, which requires larger wound incis
Externí odkaz:
https://doaj.org/article/b93fb4a180fc4893bf21a8c4fdd4b89f
Autor:
Ronil V. Chandra, Camilla A. Cohen, Tony Goldschlager, Graham Jenkin, Idrees Sher, Ronald Shimmon, Angela Vais, Tanya Badal, Kanika Jain, David Oehme, Andrew C.W. Zannettino, Chris D. Daly, Peter Ghosh
Publikováno v:
The Spine Journal. 18:491-506
Neural compression associated with lumbar disc herniation is usually managed surgically by microdiscectomy. However, 10%-20% of patients re-present with debilitating back pain, and approximately 15% require further surgery.Using an ovine model of mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498dc8bf257c8d7af1800cee56717b90
https://doi.org/10.1016/j.spinee.2017.10.008
https://doi.org/10.1016/j.spinee.2017.10.008
Autor:
Mustafa Sher, David Oehme, Julian A. Smith, Chris D. Daly, Ronil V. Chandra, Peter Ghosh, Tony Goldschlager, Idrees Sher
Publikováno v:
Spine. 44(13)
Reliability study.To evaluate the applicability and reliability of 9.4T magnetic resonance imaging (MRI) in the assessment of degenerative disc disease compared with 3T MRI.MRI is a reliable indicator of biochemical changes in the intervertebral disc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b25de7d42cdbc22d59e77f6ab9490a5
https://pubmed.ncbi.nlm.nih.gov/31205169
https://pubmed.ncbi.nlm.nih.gov/31205169
Autor:
Idrees, Sher, Ronil V, Chandra, Chris, Daly, David, Oehme, Mustafa, Sher, Peter, Ghosh, Julian, Smith, Tony, Goldschlager
Publikováno v:
Spine. 44(10)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2f0c528919f53901ae48732bba177a12
https://pubmed.ncbi.nlm.nih.gov/31046002
https://pubmed.ncbi.nlm.nih.gov/31046002
Autor:
Tanya Badal, Graham Jenkin, Chris D. Daly, Justin J. Cooper-White, Peter Ghosh, Tony Goldschlager, Ronald Shimmon, Idrees Sher, Ronil V. Chandra, David Oehme
Publikováno v:
Global Spine Journal
Study Design: Large animal research. Objective: Lumbar discectomy is the most commonly performed spinal surgical procedure. We investigated 2 large animal models of lumbar discectomy in order to study the regenerative capacity of mesenchymal stem cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::555e11e5e488f5f22e588c8cf5975cb6
https://pubmed.ncbi.nlm.nih.gov/30560038
https://pubmed.ncbi.nlm.nih.gov/30560038
Autor:
Graham Jenkin, Jiehua Wu, Courtney McDonald, John Troupis, Jeffrey V. Rosenfeld, Tony Goldschlager, Peter Ghosh, Susan Shimon, Silviu Itescu, David Oehme
Publikováno v:
Journal of Neurosurgery: Spine. 24:715-726
OBJECTIVE Disc degeneration and associated low-back pain are major causes of suffering and disability. The authors examined the potential of mesenchymal precursor cells (MPCs), when formulated with pentosan polysulfate (PPS), to ameliorate disc degen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dc19783d66a202249f59a43466b5d75
https://doi.org/10.3171/2015.8.spine141097
https://doi.org/10.3171/2015.8.spine141097
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2016 (2016)
BioMed Research International, Vol 2016 (2016)
Lower back pain is the leading cause of disability worldwide. Discogenic pain secondary to intervertebral disc degeneration is a significant cause of low back pain. Disc degeneration is a complex multifactorial process. Animal models are essential to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb67b94918041333c3cf2a9a5608655
https://doi.org/10.1155/2016/5952165
https://doi.org/10.1155/2016/5952165
Publikováno v:
Neurosurgical Review. 38:429-445
Degenerative conditions of the lumbar spine are extremely common. Ninety percent of people over the age of 60 years have degenerative change on imaging; however, only a small minority of people will require spine surgery (Hicks et al. Spine (Phila Pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bca24f3518878dc70faf231b178a96c
https://doi.org/10.1007/s10143-015-0621-7
https://doi.org/10.1007/s10143-015-0621-7
Publikováno v:
Stem Cells International
Stem Cells International, Vol 2015 (2015)
Stem Cells International, Vol 2015 (2015)
Low back pain and degenerative disc disease are a significant cause of pain and disability worldwide. Advances in regenerative medicine and cell-based therapies, particularly the transplantation of mesenchymal stem cells and intervertebral disc chond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::870ab0beb567afdd809943459da5b01d
https://doi.org/10.1155/2015/946031
https://doi.org/10.1155/2015/946031