Zobrazeno 1 - 10
of 11
pro vyhledávání: '"David O. Raemy"'
Autor:
Ramon Frick, Wendelin J. Stark, Detlef Günther, Björn Müller-Edenborn, Barbara Rothen-Rutishauser, Bodo Hattendorf, David O. Raemy, Andreas Schlicker, Beatrice Beck-Schimmer
Publikováno v:
Toxicology Letters. 205:163-172
Due to their physicochemical characteristics, metal oxide nanoparticles (NPs) interact differently with cells compared to larger particles or soluble metals. Oxidative stress and cellular metal uptake were quantified in rat type II alveolar epithelia
Autor:
Wendelin J. Stark, Peter Gehr, Robert N. Grass, David O. Raemy, Ludwig K. Limbach, Detlef Günther, Barbara Rothen-Rutishauser, Karin Birbaum, Christina Brandenberger
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 77:368-375
Nowadays, aerosol processes are widely used for the manufacture of nanoparticles (NPs), creating an increased occupational exposure risk of workers, laboratory personnel and scientists to airborne particles. There is evidence that possible adverse ef
Autor:
Alke Petri-Fink, David O. Raemy, Dimitri Vanhecke, Dorleta Jimenez de Aberasturi, Martin J. D. Clift, David Schürch, Wolfgang J. Parak, Peter Gehr, Barbara Rothen-Rutishauser
Publikováno v:
Langmuir : the ACS journal of surfaces and colloids. 30(17)
Many advances have been made in recent years in cell culture models of the epithelial barrier of the lung from simple monolayers to complex 3-D systems employing different cell types. However, the vast majority of these models still present a static
Publikováno v:
Journal of Nanobiotechnology
Journal of Nanobiotechnology, vol. 11, no. 1, pp. 29
Journal of Nanobiotechnology, vol. 11, no. 1, pp. 29
Background Plasmid DNA vaccination is a promising approach, but studies in non-human primates and humans failed to achieve protective immunity. To optimise this technology further with focus on pulmonary administration, we developed and evaluated an
Autor:
Barbara Rothen-Rutishauser, Martin J. D. Clift, Peter Gehr, Carola Endes, Alke Petri-Fink, Zulqurnain Ali, Andrea D. Lehmann, Roel P. F. Schins, Peter Wick, Wolfgang J. Parak, David O. Raemy, Christina Brandenberger
Publikováno v:
Nanotoxicology
The aim of this study was to assess the interaction of a series of well characterised nano-objects with the Gram negative bacterium Salmonella typhimurium, and how such an interaction may relate to the potential mutagenicity of nano-objects. Transmis
Autor:
Wendelin J. Stark, Barbara Rothen-Rutishauser, Christoph M. Schumacher, Martin J. D. Clift, Robert N. Grass, David O. Raemy, Peter Gehr
Publikováno v:
Particle and Fibre Toxicology, 9
Raemy, David O.; Grass, Robert N.; Stark, Wendelin J.; Schumacher, Christoph M.; Clift, Martin JD; Gehr, Peter; Rothen-Rutishauser, Barbara (2012). Effects of flame made zinc oxide particles in human lung cells-a comparison of aerosol and suspension exposures. Particle and fibre toxicology, 9(1), p. 33. London: BioMed Central 10.1186/1743-8977-9-33
Particle and Fibre Toxicology
Particle and Fibre Toxicology, Vol 9, Iss 1, p 33 (2012)
Raemy, David O.; Grass, Robert N.; Stark, Wendelin J.; Schumacher, Christoph M.; Clift, Martin JD; Gehr, Peter; Rothen-Rutishauser, Barbara (2012). Effects of flame made zinc oxide particles in human lung cells-a comparison of aerosol and suspension exposures. Particle and fibre toxicology, 9(1), p. 33. London: BioMed Central 10.1186/1743-8977-9-33
Particle and Fibre Toxicology
Particle and Fibre Toxicology, Vol 9, Iss 1, p 33 (2012)
Background Predominantly, studies of nanoparticle (NPs) toxicology in vitro are based upon the exposure of submerged cell cultures to particle suspensions. Such an approach however, does not reflect particle inhalation. As a more realistic simulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c20332362d8bea21c051639c57a4eefa
https://hdl.handle.net/20.500.11850/64834
https://hdl.handle.net/20.500.11850/64834
Autor:
Loretta Mueller, Sandro Steiner, David O. Raemy, Olga Popovicheva, Martin J. D. Clift, Peter Gehr, Jan Czerwinski, Andreas Mayer, Barbara Rothen-Rutishauser, Pierre Comte
Publikováno v:
TOXICOLOGY LETTERS
Toxicology letters
Toxicology letters
The aim of this study was to compare the biological response of a sophisticated in vitro 3D co-culture model of the epithelial airway barrier to a co-exposure of CeO(2) NPs and diesel exhaust using a realistic air-liquid exposure system. Independent
Autor:
Peter Gehr, Aftab Ahmad, Barbara Rothen-Rutishauser, Jenai M Kailey, Keith B. Neeves, Shama Ahmad, Carl W. White, Joan E. Loader, David O. Raemy
Nanoparticles (NPs) produced by nanotechnology processes have taken the field of medicine by storm. Concerns about safety of these NPs in humans, however, have recently been raised. Although studies of NP toxicity have focused on lung disease the mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66b60adc5df0b369f56f735021ee7e20
https://europepmc.org/articles/PMC3311910/
https://europepmc.org/articles/PMC3311910/
Autor:
Martin J. D. Clift, Loretta Müller, Fabian Herzog, Peter Gehr, Christina Brandenberger, David O. Raemy, Michael Gasser, Otmar Schmid, Barbara Rothen-Rutishauser
Publikováno v:
Insciences J. 1, 30-64 (2011)
In light of the increasingly abundant use of engineered nanoparticles(NPs) and the ongoing exposure to ambient ultrafine particles it is imperative that the potential for NPs to elicit adverse effects on human health is understood. In order to determ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac765390bae0a4a112d9e295ac9baa7c
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=6338
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=6338
Autor:
Robert N. Grass, Wendelin J. Stark, Fabian Blank, Christina Brandenberger, David O. Raemy, Ludwig K. Limbach, Peter Gehr, Barbara Rothen-Rutishauser, Christian Mühlfeld
Publikováno v:
Environmental sciencetechnology. 43(7)
The tremendous application potential of nanosized materials stays in sharp contrast to a growing number of critical reports of their potential toxicity. Applications of in vitro methods to assess nanoparticles are severely limited through difficultie