Zobrazeno 1 - 6
of 6
pro vyhledávání: '"David O. Nettleton"'
Autor:
Christopher J. Schwalen, Charles Babu, Swastik Phulera, Qin Hao, Daniel Wall, David O. Nettleton, Tejas P. Pathak, Piro Siuti
Publikováno v:
ACS Omega, Vol 6, Iss 44, Pp 29555-29566 (2021)
Externí odkaz:
https://doaj.org/article/14864f5a99074e72aa56e19c9b5e2d1c
Clearance of plasma PCSK9 via the asialoglycoprotein receptor mediated by heterobifunctional ligands
Autor:
Jeffrey T. Bagdanoff, Thomas M. Smith, Martin Allan, Peter O’Donnell, Zachary Nguyen, Elizabeth A. Moore, Jason Baird, Shuangxi Wang, Vanitha Subramanian, Bruno Tigani, David O. Nettleton, Lauren G. Monovich, Ian Lewis, Alec N. Flyer, Brian Granda, John W. Blankenship, David Barnes-Seeman, Kevin B. Clairmont
Publikováno v:
Cell Chemical Biology. 30:97-109.e9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cda907f4423e41fe5feee324e9c215d0
https://doi.org/10.1016/j.chembiol.2022.12.003
https://doi.org/10.1016/j.chembiol.2022.12.003
Autor:
Marcel J. De Groot, David H. Singleton, Nora K. Wallace, Jill Steidl-Nichols, Matt Deacon, David O. Nettleton, Christine Williams, Helen Boyd, David Price, James G. Boyd, Matthew D. Troutman
Publikováno v:
Journal of Medicinal Chemistry. 50:2931-2941
Novel fluorescent derivatives of dofetilide (1) have been synthesized. Analogues that feature a fluorescent probe attached through an aliphatic spacer to the central tertiary nitrogen of 1 have high affinity for the hERG channel, and affinity is depe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc1357600b6b4a733dff3290caeafd13
https://doi.org/10.1021/jm0700565
https://doi.org/10.1021/jm0700565
Autor:
David O Nettleton, Tristan S. Maurer, Odette A. Fahmi, Mary Kish, Edwin Cardenas, Sherri Boldt
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 36(8)
Although approaches to the prediction of drug-drug interactions (DDIs) arising via time-dependent inactivation have recently been developed, such approaches do not account for simple competitive inhibition or induction. Accordingly, these approaches
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c6f30329c82580942846b374c8f4692
https://pubmed.ncbi.nlm.nih.gov/18490437
https://pubmed.ncbi.nlm.nih.gov/18490437
Autor:
David H. Singleton, Helen Boyd, Jill V. Steidl-Nichols, Matt Deacon, Marcel J. de Groot, David Price, David O. Nettleton, Nora K. Wallace, Matthew D. Troutman, Christine Williams, James G. Boyd
Publikováno v:
Journal of Medicinal Chemistry; Jun2007, Vol. 50 Issue 13, p2931-2941, 11p
Publikováno v:
Archives of biochemistry and biophysics. 271(2)
The ability of nitroxide spin labels to act as oxidizers of reduced nitroxides (hydroxylamines) in biological and model systems was demonstrated. All of the nitroxides tested were able to act as oxidizing agents with respect to hydroxylamine derivati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::930d7418167f8e294c2d7ebf31327554
https://pubmed.ncbi.nlm.nih.gov/2729999
https://pubmed.ncbi.nlm.nih.gov/2729999