Zobrazeno 1 - 10
of 16
pro vyhledávání: '"David Northey"'
Autor:
David Northey, Yoshihiro Kakeji, Susan Keyes, Yoshihiko Maehara, Gulshan Ara, Yasunori Emi, Ying Nan Chen, Beverly A. Teicher
Publikováno v:
International Journal of Cancer. 67:864-870
Interleukin-II (rhIL-II) is a cytokine that has been shown to enhance the recovery of bone marrow and intestinal crypt cells after cytotoxic insult with radiation or anticancer drugs. The current study examined the effects of rhIL-II on the response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b803a7b1af0c9ffb95fa0569abbbfbc
https://doi.org/10.1002/(sici)1097-0215(19960917)67:6<864::aid-ijc17>3.0.co
https://doi.org/10.1002/(sici)1097-0215(19960917)67:6<864::aid-ijc17>3.0.co
Publikováno v:
Radiation Oncology Investigations. 4:221-230
Radiation therapy is very useful in the treatment of prostate cancer; however, local treatment failure still occurs in the majority of patients with locally advanced disease. The growth and progression of tumors involve signaling through protein grow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ca6bf7e677a63b068d37341a9b6a302
https://doi.org/10.1002/(sici)1520-6823(1996)4:5<221::aid-roi4>3.0.co
https://doi.org/10.1002/(sici)1520-6823(1996)4:5<221::aid-roi4>3.0.co
Publikováno v:
Cancer Chemotherapy and Pharmacology. 36:165-171
Antifolates have been shown to increase the DNA strand breaks produced by the topoisomerase inhibitor etoposide. PT523 is a potent new antifolate that cannot be polyglutamated. Human SCC-25 squamous carcinoma cells were exposed to methotrexate, trime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88b53858c1d9aaec7c3331f17c315f3e
https://doi.org/10.1007/bf00689203
https://doi.org/10.1007/bf00689203
Publikováno v:
Cancer Chemotherapy and Pharmacology. 35:423-431
The expression of several early-response genes and genes associated with malignant disease was assessed in the EMT-6/parent tumor and the EMT-6/CTX and EMT-6/CDDP in vivo resistant tumor lines growing as tumors or as monolayers in culture. In the abs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::549229926d418cff4ea421745e049cfd
https://doi.org/10.1007/s002800050257
https://doi.org/10.1007/s002800050257
Publikováno v:
Cancer Chemotherapy and Pharmacology. 34:235-241
The ability of the collagenase inhibitor minocycline and of beta-carotene to act as positive modulators of cytotoxic anticancer agents was assessed in vitro and in vivo. Cell-culture studies were conducted using the human SCC-25 squamous carcinoma ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea270a0699733d3c4389d891f8bfbab
https://doi.org/10.1007/bf00685083
https://doi.org/10.1007/bf00685083
Autor:
Sylvia A. Holden, Gulshan Ara, Ying-Nan Chen, Timothy Korbut, David Northey, Beverly A. Teicher
Publikováno v:
Cancer Chemotherapy and Pharmacology. 34:515-521
CAI (NSC 609974; L651582), a new agent that has demonstrated antimetastatic activity in vitro and in vivo, was not very cytotoxic toward EMT-6 mouse mammary carcinoma cells in culture or toward FSaIIC fibrosarcoma cells in vivo. Coexposure of EMT-6 c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f7f2778165d94134889f4a26936fd76
https://doi.org/10.1007/bf00685664
https://doi.org/10.1007/bf00685664
Publikováno v:
International journal of oncology. 10(6)
The cytokine interleukin-11 (rhIL-11) has been shown to enhance the recovery of bone marrow, oral epithelium and intestinal crypt cells after cytotoxic insult by anticancer drugs or ionizing radiation. 5-Fluorouracil based chemotherapy and radiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dc61a05cb36827510fcac5b19a030cf
https://pubmed.ncbi.nlm.nih.gov/21533487
https://pubmed.ncbi.nlm.nih.gov/21533487
Publikováno v:
International journal of oncology. 11(2)
Lisofylline, a dimethylxanthine derivative, has been shown to block the induction of hematopoietic growth inhibitors produced in response to cytotoxic anticancer therapy. In the current study, mice bearing established EMT-6 mammary carcinoma were tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c821a247ebb5cb59d27344d2ad679320
https://pubmed.ncbi.nlm.nih.gov/21528210
https://pubmed.ncbi.nlm.nih.gov/21528210
Autor:
Beverly A. Teicher, Gulshan Ara, Terence S. Herman, Chul S. Ha, David Northey, Sylvia A. Holden
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 118:509-514
Many anticancer drugs require oxygen to be cytotoxic or are selectively cytotoxic toward cells under oxygenated conditions. The effects of the dilute perfluorochemical emuolsion Fluosol with a wide variety of chemotherapeutic agents have been explore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::848d80f13819f0e9f01b57aa0359ec0f
https://doi.org/10.1007/bf01225265
https://doi.org/10.1007/bf01225265
Autor:
Naiyer A. Rizvi, Julia Wong, Victor T.W. Chan, Gulshan Ara, Beverly A. Teicher, Joseph Paul Eder, Yee W. Wong, David Northey
Publikováno v:
Cancer chemotherapy and pharmacology. 42(4)
The DNA topoisomerases I and II are the target of several clinically important antineoplastic agents which produce DNA cleavage by stabilization of the covalent DNA-protein bond with resultant cell death after DNA synthesis is attempted. Depletion of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20c8bef93f4a1e0bc99305eafb31664a
https://pubmed.ncbi.nlm.nih.gov/9744779
https://pubmed.ncbi.nlm.nih.gov/9744779