Zobrazeno 1 - 10
of 35
pro vyhledávání: '"David Nickle"'
Autor:
Daniel J DeAngelo, Chia-Cheng Li, Amit Verma, Mariano Severgnini, David Nickle, Guillermo Garcia-Manero, Uwe Platzbecker, Reinhard von Roemeling, Klaus H Metzeler, Eric S Winer, Gaurav S Choudhary, Wanying Zhao, Maureen Lane, Alyssa Masciarelli, Dora Ferrari, Cole Gallagher, Samantha Carlisle
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/2e667ab0e236414281a1be5dcc4a281e
Autor:
Ana I. Hernández Cordero, Xuan Li, Chen Xi Yang, Stephen Milne, Yohan Bossé, Philippe Joubert, Wim Timens, Maarten van den Berge, David Nickle, Ke Hao, Don D. Sin
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Abstract Cell entry of SARS-CoV-2, the novel coronavirus causing COVID-19, is facilitated by host cell angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2). We aimed to identify and characterize genes that are co-expre
Externí odkaz:
https://doaj.org/article/04a4ce5f742b4fb4a05cf20cbace41a1
Autor:
Xiang Zeng, Judith M. Vonk, Diana A. van der Plaat, Alen Faiz, Peter D. Paré, Philippe Joubert, David Nickle, Corry-Anke Brandsma, Hans Kromhout, Roel Vermeulen, Xijin Xu, Xia Huo, Kim de Jong, H. Marike Boezen
Publikováno v:
Environment International, Vol 122, Iss , Pp 263-269 (2019)
Respiratory symptoms are important indicators of respiratory diseases. Both genetic and environmental factors contribute to respiratory symptoms development but less is known about gene-environment interactions. We aimed to assess interactions betwee
Externí odkaz:
https://doaj.org/article/b4994d91514f4d0585ddd4d3e71d0d32
Autor:
Laura Carter, Andrea Wang-Gillam, Johanna Bendell, Wungki Park, Wells Messersmith, Drew Rasco, Lei Zhou, Jean-Marie Bruey, Beatrice Ferguson, Jakob Dupont, Marya Chaney, Johann De Bono, David Nickle, Anna Galkin
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/4c3856eeaeb64d86ae0c6a78be6a0f14
Autor:
Judong Shen, Devan V. Mehrotra, Mary Beth Dorr, Zhen Zeng, Junhua Li, Xun Xu, David Nickle, Emily R. Holzinger, Aparna Chhibber, Mark H. Wilcox, Rebecca L. Blanchard, Peter M. Shaw
Publikováno v:
mSphere, Vol 5, Iss 3 (2020)
ABSTRACT Bezlotoxumab is a human monoclonal antibody against Clostridium difficile toxin B, indicated to prevent recurrence of C. difficile infection (rCDI) in high-risk adults receiving antibacterial treatment for CDI. An exploratory genome-wide ass
Externí odkaz:
https://doaj.org/article/adb561e16b8649aeaf98ce58ff6ef478
Autor:
Julie Weidner, Linnea Jarenbäck, Kim de Jong, Judith M. Vonk, Maarten van den Berge, Corry-Anke Brandsma, H. Marike Boezen, Don Sin, Yohan Bossé, David Nickle, Jaro Ankerst, Leif Bjermer, Dirkje S. Postma, Alen Faiz, Ellen Tufvesson
Publikováno v:
Respiratory Research, Vol 18, Iss 1, Pp 1-14 (2017)
Abstract Background It has been observed that mice lacking the sulfatase modifying factor (Sumf1) developed an emphysema-like phenotype. However, it is unknown if SUMF1 may play a role in Chronic Obstructive Pulmonary Disease (COPD) in humans. The ai
Externí odkaz:
https://doaj.org/article/9433dfb75385440c95d461a856a8c228
Autor:
Jean-Christophe Bérubé, Nathalie Gaudreault, Emilie Lavoie-Charland, Laura Sbarra, Cyndi Henry, Anne-Marie Madore, Peter D. Paré, Maarten van den Berge, David Nickle, Michel Laviolette, Catherine Laprise, Louis-Philippe Boulet, Yohan Bossé
Publikováno v:
Canadian Respiratory Journal, Vol 2016 (2016)
Susceptibility genes of asthma may be more successfully identified by studying subgroups of phenotypically similar asthma patients. This study aims to identify single nucleotide polymorphisms (SNPs) associated with asthma in French Canadian adult wom
Externí odkaz:
https://doaj.org/article/83062a9100974955be3737c98d7a5cd3
Autor:
Matteo Dugo, Chiara E Cotroneo, Emilie Lavoie-Charland, Matteo Incarbone, Luigi Santambrogio, Lorenzo Rosso, Maarten van den Berge, David Nickle, Peter D Paré, Yohan Bossé, Tommaso A Dragani, Francesca Colombo
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0167460 (2016)
Sex and age strongly influence the pathophysiology of human lungs, but scarce information is available about their effects on pulmonary gene expression.We followed a discovery-validation strategy to identify sex- and age-related transcriptional diffe
Externí odkaz:
https://doaj.org/article/730f9ecf9f5c484a9c0bc521d0c1e3c9
Autor:
Louise V Wain, Ian Sayers, María Soler Artigas, Michael A Portelli, Eleftheria Zeggini, Ma'en Obeidat, Don D Sin, Yohan Bossé, David Nickle, Corry-Anke Brandsma, Anders Malarstig, Ciara Vangjeli, Scott A Jelinsky, Sally John, Iain Kilty, Tricia McKeever, Nick R G Shrine, James P Cook, Shrina Patel, Tim D Spector, Edward J Hollox, Ian P Hall, Martin D Tobin
Publikováno v:
PLoS Genetics, Vol 10, Iss 5, p e1004314 (2014)
Chronic obstructive pulmonary disease (COPD) is a leading cause of global morbidity and mortality and, whilst smoking remains the single most important risk factor, COPD risk is heritable. Of 26 independent genomic regions showing association with lu
Externí odkaz:
https://doaj.org/article/80130c5b7ffc455eaf146a6e0dad6b17
Autor:
Maxime Lamontagne, Christian Couture, Dirkje S Postma, Wim Timens, Don D Sin, Peter D Paré, James C Hogg, David Nickle, Michel Laviolette, Yohan Bossé
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e70220 (2013)
Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of mortality worldwide. Recent genome-wide association studies (GWAS) have identified robust susceptibility loci associated with COPD. However, the mechanisms mediating the risk
Externí odkaz:
https://doaj.org/article/ff668192e9db4130ad4b399ac5b3025c