Zobrazeno 1 - 10
of 32
pro vyhledávání: '"David N. Quan"'
Autor:
Amin Zargar, David N. Quan, Karen K. Carter, Min Guo, Herman O. Sintim, Gregory F. Payne, William E. Bentley
Publikováno v:
mBio, Vol 6, Iss 2 (2015)
ABSTRACT There have been many studies on the relationship between nonpathogenic bacteria and human epithelial cells; however, the bidirectional effects of the secretomes (secreted substances in which there is no direct bacterium-cell contact) have ye
Externí odkaz:
https://doaj.org/article/75e3a4521f5348dfb51fd872d8b89a98
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 4, p e1004781 (2016)
Quorum Sensing (QS) drives coordinated phenotypic outcomes among bacterial populations. Its role in mediating infectious disease has led to the elucidation of numerous autoinducers and their corresponding QS signaling pathways. Among them, the Lsr (L
Externí odkaz:
https://doaj.org/article/d375f4097b1e4a3d87b6b2b16ff712c2
Autor:
William E. Bentley, David N. Quan, Reza Ghodssi, Pradeep Ramiah Rajasekaran, Liangbing Hu, Ashley A. Chapin, Jens Herberholz
Publikováno v:
Microsystems & Nanoengineering, Vol 6, Iss 1, Pp 1-13 (2020)
Gut–brain axis (GBA) communication relies on serotonin (5-HT) signaling between the gut epithelium and the peripheral nervous system, where 5-HT release patterns from the basolateral (i.e., bottom) side of the epithelium activate nerve afferents. T
Autor:
Boce Zhang, Jinglin Zhang, William E. Bentley, Chen-Yu Tsao, Lei Mei, David N. Quan, Yi Liu, Qin Wang, Ying Li, Yongguang Guan, Gregory F. Payne
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 172:197-206
Quorum sensing (QS) enables intercellular communication after bacterial cells sense the autoinducers have reached or exceeded a critical concentration. Selectively amplifying specific bacterial “quorum” activity at a lower cell density is still a
Autor:
William E. Bentley, Reza Ghodssi, David N. Quan, Ashley A. Chapin, Pradeep Ramiah Rajasekaran, Jens Herberholz
Publikováno v:
Microsystems & Nanoengineering, Vol 6, Iss 1, Pp 1-12 (2020)
This work presents a 3D-printed, modular, electrochemical sensor-integrated transwell system for monitoring cellular and molecular events in situ without sample extraction or microfluidics-assisted downstream omics. Simple additive manufacturing tech
Autor:
Hsuan‐Chen Wu, Chen‐Yu Tsao, David N Quan, Yi Cheng, Matthew D Servinsky, Karen K Carter, Kathleen J Jee, Jessica L Terrell, Amin Zargar, Gary W Rubloff, Gregory F Payne, James J Valdes, William E Bentley
Publikováno v:
Molecular Systems Biology, Vol 9, Iss 1, Pp n/a-n/a (2013)
Escherichia coli were genetically modified to enable programmed motility, sensing, and actuation based on the density of features on nearby surfaces. Then, based on calculated feature density, these cells expressed marker proteins to indicate phenoty
Externí odkaz:
https://doaj.org/article/aef0276ba3144a94ae631b13f46f454d
Autor:
David N Quan, William E Bentley
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 8, p e1002637 (2012)
Bacterial cell-cell communication is mediated by small signaling molecules known as autoinducers. Importantly, autoinducer-2 (AI-2) is synthesized via the enzyme LuxS in over 80 species, some of which mediate their pathogenicity by recognizing and tr
Externí odkaz:
https://doaj.org/article/c69396b261404f189d4b75fdcba963f1
Autor:
William E. Bentley, Yongguang Guan, Yingying Song, Gregory F. Payne, Qin Wang, Ying Li, Yi Liu, Boce Zhang, Lei Mei, David N. Quan, Chen-Yu Tsao
Publikováno v:
Environmental Microbiology. 20:2585-2597
Quorum sensing (QS) exists widely among bacteria, enabling a transition to multicellular behaviour after bacterial populations reach a particular density. The coordination of multicellularity enables biotechnological application, dissolution of biofi
Autor:
Nadia Abutaleb, Erica Choi, William E. Bentley, David N. Quan, Jessica L. Terrell, Gregory F. Payne, Amin Zargar
Publikováno v:
Biotechnology and Bioengineering. 114:407-415
Microbial cells have for many years been engineered to facilitate efficient production of biologics, chemicals, and other compounds. As the "metabolic" burden of synthetic genetic components can impair cell performance, microbial consortia are being
Autor:
Haig Pakhchanian, Gregory F. Payne, David N. Quan, Tanya Tschirhart, Chen-Yu Tsao, Narendranath Bhokisham, William E. Bentley
Publikováno v:
Metabolic Engineering. 38:1-9
Motivations for the hierarchical assembly of protein complexes are diverse spanning biosensing, biomedical and bioreactor applications. The assembly processes should be simple, scalable, versatile, and biologically benign to minimize loss of componen