Zobrazeno 1 - 10
of 16
pro vyhledávání: '"David N. Powers"'
Autor:
Nicole Azer, Nicholas Trunfio, Erica J. Fratz‐Berilla, Jin Sung Hong, Jackie Cullinan, Talia Faison, Cyrus D. Agarabi, David N. Powers
Publikováno v:
Biotechnology Progress.
Autor:
null Nicole Azer, null Nicholas Trunfio, null Erica J. Fratz‐Berilla, null Jin Sung Hong, null Jackie Cullinan, null Talia Faison, null Cyrus D. Agarabi, null David N. Powers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::901347a56680e707d08894746390c2ac
https://doi.org/10.1002/btpr.3347/v2/response1
https://doi.org/10.1002/btpr.3347/v2/response1
With the transition toward continuous bioprocessing, process analytical technology (PAT) is becoming necessary for rapid and reliable in-process monitoring during biotherapeutics manufacturing. Bioprocess 4.0 is looking to build an end-to-end bioproc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79249e43779844510c9bc2df3f1785fc
https://doi.org/10.1101/2022.12.22.521623
https://doi.org/10.1101/2022.12.22.521623
Autor:
Sai Rashmika Velugula-Yellela, Kurt Brorson, Cyrus Agarabi, David N. Powers, Talia Faison, Erica J. Fratz‐Berilla, Casey Kohnhorst
Publikováno v:
Biotechnology and Bioengineering
Mycoplasma contamination events in biomanufacturing facilities can result in loss of production and costly cleanups. Mycoplasma may survive in mammalian cell cultures with only subtle changes to the culture and may penetrate the 0.2 µm filters often
Autor:
Wells W. Wu, Rong-Fong Shen, Cyrus Agarabi, Su-Ryun Kim, Shweta Kotian, Tongzhong Ju, Martina Kosikova, Hang Xie, Guozhang Zou, David N. Powers
Publikováno v:
Journal of Biological Chemistry. 293:19277-19289
Influenza viruses cause contagious respiratory infections, resulting in significant economic burdens to communities. Production of influenza-specific Igs, specifically IgGs, is one of the major protective immune mechanisms against influenza viruses.
Autor:
Sai Rashmika Velugula-Yellela, David N. Powers, Ryan J. Graham, Nicholas Trunfio, Erica J. Fratz‐Berilla, Adil Mohammad, Cyrus Agarabi, Talia Faison, Casey Kohnhorst, Phillip Angart
Publikováno v:
Biotechnology and Bioengineering
A mycoplasma contamination event in a biomanufacturing facility can result in costly cleanups and potential drug shortages. Mycoplasma may survive in mammalian cell cultures with only subtle changes to the culture and penetrate the standard 0.2‐µm
Autor:
Anneliese Faustino, Cyrus Agarabi, Nicholas Trunfio, Phillip Angart, Sai Rashmika Velugula-Yellela, David N. Powers
Publikováno v:
Biotechnology Progress
Use of multivariate data analysis for the manufacturing of biologics has been increasing due to more widespread use of data‐generating process analytical technologies (PAT) promoted by the US FDA. To generate a large dataset on which to apply these
Autor:
Yifan Wang, Cyrus Agarabi, Sai Rashmika Velugula-Yellela, Phillip Angart, Seongkyu Yoon, Brittany Chavez, Nicholas Trunfio, Erica J. Fratz‐Berilla, David N. Powers
Publikováno v:
Biotechnology Progress
Real‐time monitoring of cell cultures in bioreactors can enable expedited responses necessary to correct potential batch failure perturbations which may normally go undiscovered until the completion of the batch and result in failure. Currently, an
Autor:
Adarsh K. Mayank, Vijaya Pandey, Tanu Sharma, David N. Powers, Tisha Haque, Shima Rayatpisheh, William D. Barshop, Ajay A. Vashisht, James A. Wohlschlegel
Publikováno v:
Mol Cell
Molecular cell, vol 75, iss 2
Molecular cell, vol 75, iss 2
The iron sensing protein FBXL5 is the substrate adaptor for a SKP1-CUL1-RBX1 E3 ubiquitin ligase complex that regulates the degradation of iron regulatory proteins (IRPs). Here we describe a mechanism of FBXL5 regulation involving its interaction wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6b7e2d67ccbbb2d5b12527f6df0d570
https://europepmc.org/articles/PMC6660392/
https://europepmc.org/articles/PMC6660392/
Autor:
Cyrus Agarabi, Erica J. Fratz‐Berilla, David N. Powers, Talia Faison, Casey Kohnhorst, Phillip Angart, Sai Rashmika Velugula-Yellela, Anneliese Faustino
Publikováno v:
Journal of visualized experiments : JoVE. (147)
Monoclonal antibodies (mAbs) are one of the most popular and well-characterized biological products manufactured today. Most commonly produced using Chinese hamster ovary (CHO) cells, culture and process conditions must be optimized to maximize antib