Výsledky vyhledávání - "David N. Nevin"

A novel A–>G mutation in intron I of the hepatic lipase gene leads to alternative splicing resulting in enzyme deficiency

Autor: David N. Nevin, Silvia Santamarina-Fojo, Klaus A. Dugi, Korbinian Brand, John D. Brunzell

Publikováno v: Journal of Lipid Research, Vol 37, Iss 6, Pp 1213-1223 (1996)

We have identified the underlying molecular de- fect in a patient with hepatic lipase (HL) deficiency present- ing with hypertriglyceridemia and premature cardiovascular disease. DNA sequencing of polymerase chain reaction (PCR) amplified DNA and dig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ea089e390e1277781adf545d8435d9c
http://www.sciencedirect.com/science/article/pii/S0022227520391513

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Apolipoprotein B and a second major gene locus contribute to phenotypic variation of spontaneous hypercholesterolemia in pigs

Autor: Mary E. Kaiser, Alan D. Attie, John Blangero, R.J. Aiello, Patricia J. Uelmen, David N. Nevin, David L. Ebert, Thomas D. Dyer, Jean W. MacCluer

Publikováno v: Arteriosclerosis and Thrombosis: A Journal of Vascular Biology. 14:409-419

The Lpb5 apolipoprotein B (apoB) allele occurs in pigs with spontaneous hypercholesterolemia. Low-density lipoprotein (LDL) from these pigs binds to the LDL receptor with a lower affinity and is cleared from the circulation more slowly than control p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a90b3322c409e8e9ceb9504b6dfcc3b9
https://doi.org/10.1161/01.atv.14.3.409

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Increased dietary micronutrients decrease serum homocysteine concentrations in patients at high risk of cardiovascular disease

Autor: Cynthia D. Morris, Molly E. Reusser, David A. McCarron, Suzanne Oparil, David N. Nevin, Penny M. Kris-Etherton, Lawrence M. Resnick, Sharon R. Clark, Margaret McMahon, Rebecca L. Eastgard, Jill A. Metz, Alan Chait, Geoffrey W. Snyder, R. Brian Haynes, M. Rene Malinow, Judith S. Stern, F. Xavier Pi-Sunyer, Scott Holcomb, Daniel C. Hatton

Publikováno v: The American journal of clinical nutrition. 70(5)

BACKGROUND Elevated blood homocysteine is a risk factor for cardiovascular disease. A 5-micromol/L increase is associated with an approximately 70% increase in relative risk of cardiovascular disease in adults. For patients with established risk fact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7183b5b5f9a210090773a852140c6e04
https://pubmed.ncbi.nlm.nih.gov/10539749

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