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pro vyhledávání: '"David N. Hammond"'
Publikováno v:
Growth Factors. 8:35-39
The sympathetic nervous system exerts a trophic-mitogenic effect on C-1300 mouse neuroblastoma. We now report that the trophic factor present in freshly excised sympathetic ganglia from newborn rats enhances survival and process formation of the cell
Publikováno v:
Molecular Brain Research. 16:168-172
The immortalized septal cell line, SN56 B5 G4, generated by the fusion of mouse septal area cells and neuroblastoma cells, was used to determine if nimodipine, an antagonist of voltage sensitive calcium 'L' channels, might act in a neuroprotective fa
Publikováno v:
Brain Research. 558:197-208
Neurofilament protein expression was examined immunochemically in a neuronal cell line derived from postnatal day 21 septal tissue. The SN48.1p cell line was found to constitutively synthesize an array of neurofilament proteins typical of a mature ne
Publikováno v:
Brain Research. 512:190-200
Studies employing primary cells to determine the molecular basis of neuronal development and selective synaptogenesis in the central nervous system are limited by cellular heterogeneity. Clonal hybrid cell lines derived from a particular region of br
Publikováno v:
Developmental Brain Research. 52:219-228
Studies of the development of the central nervous system would be greatly facilitated by the ability to immortalize neuronal tissue from a broad range of ages. We have previously used somatic cell fusion techniques to generate neuronal cell lines fro
Autor:
David N. Hammond, Jeong-Hoon Kim
Publikováno v:
Brain research. 671(2)
The trisomy 16 mouse is a genetic model of Down syndrome. Clonal cell lines were developed from trisomic as well as euploid embryonic mouse septal cells by introduction of thermolabile large T antigen mutant of SV 40. The cell lines underwent morphol
Autor:
Aaron P. Fox, P.J. Kontur, David N. Hammond, Bruce H. Wainer, Lisa Won, Alfred Heller, Hyung K. Choi, Philip C. Hoffmann
Publikováno v:
Brain research. 552(1)
To facilitate the study of trophic interactions between mesencephalic dopaminergic neurons and their target cells, clonal hybrid cell lines have been developed from rostral mesencephalic tegmentum (RMT) of the 14-day-old embryonic mouse employing som
Publikováno v:
Journal of autism and developmental disorders. 21(1)
Although many reviews (Golden, 1987; Gilberg, 1988) have cited an association of tuberous sclerosis with autism and 2 of 24 subjects with infantile autism according to "Rutter 's criteria" have been reported in a table (Riikonen & Amnell, 1981), only
Publikováno v:
Basic, Clinical, and Therapeutic Aspects of Alzheimer’s and Parkinson’s Diseases ISBN: 9781468458466
Basal forebrain cholinergic cells are prominently affected in Alzheimer’s disease (AD) (Hefti and Weiner, 1986). Choline acetyltransferase (ChAT) is decreased in cholinergic target areas such as the hippocampus and neocortex, and there is a loss of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1efde9b5544ba0a9f125fe3f093b395f
https://doi.org/10.1007/978-1-4684-5844-2_128
https://doi.org/10.1007/978-1-4684-5844-2_128
Autor:
David N. Hammond
Publikováno v:
Neurobiology of aging. 10(5)
Neurite outgrowth in Alzheimer's disease may well be a multifactorial phenomenon. Recent evidence suggests possible roles for the protease inhibitor domain of the 751 amino acid amyloid precursor protein (APP), as well as for the 695 amino acid APP.