Zobrazeno 1 - 10
of 47
pro vyhledávání: '"David N Drechsel"'
Autor:
Tobias Boothe, Lennart Hilbert, Michael Heide, Lea Berninger, Wieland B Huttner, Vasily Zaburdaev, Nadine L Vastenhouw, Eugene W Myers, David N Drechsel, Jochen C Rink
Publikováno v:
eLife, Vol 6 (2017)
In light microscopy, refractive index mismatches between media and sample cause spherical aberrations that often limit penetration depth and resolution. Optical clearing techniques can alleviate these mismatches, but they are so far limited to fixed
Externí odkaz:
https://doaj.org/article/e3c0f94e6daf40dab29eecc4b1f6c5ff
Autor:
Patrick H.N. Celie, Georg Huber, Christian Benda, Anita Lehner, Hüseyin Besir, Cindy Chang, Paola Storici, Peggy Stolt-Bergner, Joop van den Heuvel, Astrid Sander, Gwynn Pardee, Sabine Suppmann, Regis P. Lemaitre, Barbara Giabbai, Wolfgang Knecht, Isabel Zaror, Daniel Weinbruch, Linda H.L. Lua, Tim Bergbrede, Ines Racke, Judith Scholz, David N. Drechsel, Arie Geerlof, Magda Stadnik, Ariane Fischer, Kristina Nordén, Kim Remans
Publikováno v:
J. Struct. Biol. 203, 71-80 (2018)
Baculovirus-insect cell expression system has become one of the most widely used eukaryotic expression systems for heterologous protein production in many laboratories. The availability of robust insect cell lines, serum-free media, a range of vector
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48ca00a22d4e1f9346a9509793321a5c
https://doi.org/10.1016/j.jsb.2018.03.004
https://doi.org/10.1016/j.jsb.2018.03.004
Publikováno v:
Proceedings of the National Academy of Sciences. 114:12501-12506
Salamanders exhibit extensive regenerative capacities and serve as a unique model in regeneration research. However, due to the lack of targeted gene knockin approaches, it has been difficult to label and manipulate some of the cell populations that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65ac27f4ac04b283857d45c4c398c500
https://doi.org/10.1073/pnas.1706855114
https://doi.org/10.1073/pnas.1706855114
Autor:
Martine Ruer, Timothy J. Mitchison, Elvan Boke, Anthony A. Hyman, Martin Wühr, Steven P. Gygi, David N. Drechsel, Margaret Coughlin, Regis P. Lemaitre, Simon Alberti
Publikováno v:
Cell. 166:637-650
Most vertebrate oocytes contain a Balbiani body, a large, non-membrane-bound compartment packed with RNA, mitochondria, and other organelles. Little is known about this compartment, though it specifies germline identity in many non-mammalian vertebra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bde0d1e21288f2b9aa6361c1078949a
https://doi.org/10.1016/j.cell.2016.06.051
https://doi.org/10.1016/j.cell.2016.06.051
Publikováno v:
Nature. 533:407-410
In salamanders, grafting of a left limb blastema onto a right limb stump yields regeneration of three limbs, the normal limb and two 'supernumerary' limbs. This experiment and other research have shown that the juxtaposition of anterior and posterior
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::392c58ef958bebdeb7f3ec82e4566754
https://doi.org/10.1038/nature17972
https://doi.org/10.1038/nature17972
Autor:
Barbara Borgonovo, Teymuras V. Kurzchalia, Lei Xing, Aliona Bogdanova, Janelle L. Lauer, Christos Chinopoulos, Patrick Keller, Anneline Pinson, Takashi Namba, Michaela Wilsch-Bräuninger, Wieland B. Huttner, Nereo Kalebic, Anna Shevchenko, Judit Doczi, David N. Drechsel, Pauline Wimberger, Samir Vaid, Katherine S. Long
Publikováno v:
Namba, T, Dóczi, J, Pinson, A, Xing, L, Kalebic, N, Wilsch-Bräuninger, M, Long, K R, Vaid, S, Lauer, J, Bogdanova, A, Borgonovo, B, Shevchenko, A, Keller, P, Drechsel, D, Kurzchalia, T, Wimberger, P, Chinopoulos, C & Huttner, W B 2020, ' Human-Specific ARHGAP11B Acts in Mitochondria to Expand Neocortical Progenitors by Glutaminolysis ', Neuron, vol. 105, no. 5, pp. 867-881.e9 . https://doi.org/10.1016/j.neuron.2019.11.027
The human-specific gene ARHGAP11B is preferentially expressed in neural progenitors of fetal human neocortex and increases abundance and proliferation of basal progenitors (BPs), which have a key role in neocortex expansion. ARHGAP11B has therefore b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6a7d7774595ce16c0f1a58b0761160c
https://doi.org/10.1016/j.neuron.2019.11.027
https://doi.org/10.1016/j.neuron.2019.11.027
Autor:
Regis P. Lemaitre, Jeffrey B. Woodruff, Barbara Borgonovo, Aliona Bogdanova, David N. Drechsel
Publikováno v:
BMC Biotechnology
BMC Biotechnology, Vol 19, Iss 1, Pp 1-11 (2019)
BMC Biotechnology, Vol 19, Iss 1, Pp 1-11 (2019)
Background Baculovirus-mediated expression in insect cells is a powerful approach for protein production. However, many existing methods are time-consuming, offer limited options for protein tagging, and are unsuitable for secreted proteins requiring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ccb6b6220a16abb833e8aa58d0bdf77
https://pubmed.ncbi.nlm.nih.gov/30925874
https://pubmed.ncbi.nlm.nih.gov/30925874
Autor:
Titus M. Franzmann, Avinash Patel, Stoyno S. Stoynov, Julia Mahamid, Anthony A. Hyman, Nicola Maghelli, Marcus Jahnel, Simon Alberti, Eugene W. Myers, Martin Weigert, Stephan W. Grill, Shambaditya Saha, Ina Poser, Hyun O. Lee, Shovamayee Maharana, Louise Jawerth, David N. Drechsel, Loic Royer, Marco Y. Hein, Andrej Pozniakovski
Publikováno v:
Cell
SummaryMany proteins contain disordered regions of low-sequence complexity, which cause aging-associated diseases because they are prone to aggregate. Here, we study FUS, a prion-like protein containing intrinsically disordered domains associated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6992eb008e3a2d4aa41bfe2c02f6504f
https://doi.org/10.1016/j.cell.2015.07.047
https://doi.org/10.1016/j.cell.2015.07.047
Autor:
Michael Heide, Nadine L. Vastenhouw, Eugene W. Myers, Jochen C. Rink, Lennart Hilbert, Tobias Boothe, David N. Drechsel, Vasily Zaburdaev, Wieland B. Huttner, Lea Berninger
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c48921aca0fd48f7d01245c7ef95a688
https://doi.org/10.7554/elife.27240.022
https://doi.org/10.7554/elife.27240.022
Autor:
Nadine L. Vastenhouw, Shai R. Joseph, Martina Augsburg, Marc Gentzel, Andrej Shevchenko, Frank Buchholz, Aliona Bogdanova, Mukesh Kumar, David N. Drechsel
Absolute quantification of proteins elucidates the molecular composition, regulation and dynamics of multiprotein assemblies and networks. Here we report on a method termed MS Western that accurately determines the molar abundance of dozens of user-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6edf88340b04427904229b6d5f6f403c