Zobrazeno 1 - 10
of 45
pro vyhledávání: '"David N, Guilfoyle"'
Autor:
Morris H. Baslow, David N. Guilfoyle
Publikováno v:
Biomolecules, Vol 5, Iss 2, Pp 635-646 (2015)
N-acetyl-l-histidine (NAH) is a prominent biomolecule in brain, retina and lens of poikilothermic vertebrates. In fish lens, NAH exhibits an unusual compartmentalized metabolism. It is synthesized from L-histidine (His) and acetyl Co-enzyme A. Howeve
Externí odkaz:
https://doaj.org/article/a818b09af1294fa6a93a315e080243d7
Autor:
Rishi R. Agrawal, Kathleen Shannon, Ernest Fraenkel, Steven S. Gross, David N. Guilfoyle, Helen Y. Figueroa, Allissa Dillman, Karen Duff, Archana Ashok, Tal Nuriel, Estela Area-Gomez, Marta Pera, Hirra A. Arain, Qiuying Chen, Mark R. Cookson, Leila Pirhaji, Delfina Larrea
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-20 (2020)
Scientific Reports
Scientific Reports
The ε4 allele of apolipoprotein E (APOE) is the dominant genetic risk factor for late-onset Alzheimer’s disease (AD). However, the reason for the association between APOE4 and AD remains unclear. While much of the research has focused on the abili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45568ad65135cb2eadd210e151d3591f
http://link.springer.com/article/10.1038/s41598-020-61142-8
http://link.springer.com/article/10.1038/s41598-020-61142-8
Autor:
David N. Guilfoyle, Fumitoshi Irie, Yu Yamaguchi, Aditi Naik, Chiye Aoki, Jan Hrabe, Sabina Hrabetova, Jasmina Isakovic, Ang D. Sherpa
Publikováno v:
Neurochem Res
Brain white matter is the means of efficient signal propagation in brain and its dysfunction is associated with many neurological disorders. We studied the effect of hyaluronan deficiency on the integrity of myelin in murine corpus callosum. Conditio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b49c63574336a7c2f73d8962c10fe6d
https://doi.org/10.1007/s11064-019-02819-z
https://doi.org/10.1007/s11064-019-02819-z
Publikováno v:
Journal of Glycomics and Metabolism. 1:23-28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc3c1547666078bb3f6a738574b912b3
https://doi.org/10.14302/issn.2572-5424.jgm-17-1482
https://doi.org/10.14302/issn.2572-5424.jgm-17-1482
Autor:
Alvin H. Bachman, Christopher K. Cain, Robert M. Sears, Morris H. Baslow, David N. Guilfoyle, Donald A. Wilson, Scott Gerum
Publikováno v:
NMR in Biomedicine. 29:1678-1687
Brain activation studies in humans have shown the dynamic nature of neuronal N-acetylaspartate (NAA) and N-acetylaspartylglutamate (NAAG) based on changes in their MRS signals in response to stimulation. These studies demonstrated that upon visual st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::529f4a488c71d490d0da9ff69f704a05
https://doi.org/10.1002/nbm.3629
https://doi.org/10.1002/nbm.3629
Autor:
Morris H. Baslow, David N. Guilfoyle
Publikováno v:
Journal of Glycomics and Metabolism. 1:25-36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d7cec7edce79353108e5c24bbaf0f73
https://doi.org/10.14302/issn.2572-5424.jgm-16-1028
https://doi.org/10.14302/issn.2572-5424.jgm-16-1028
Autor:
Steven S. Gross, Qiuying Chen, Ernest Fraenkel, Archana Ashok, Tal Nuriel, Allissa Dillman, David N. Guilfoyle, Leila Pirhaji, Karen Duff, Estela Area-Gomez, Mark R. Cookson, Hirra A. Arain, Helen Y. Figueroa, Marta Pera, Kathleen Shannon, Delfina Larrea
The ε4 allele of apolipoprotein E (APOE) is the dominant genetic risk factor for late-onset Alzheimer’s disease (AD). However, the reason for the association between APOE4 and AD remains unclear. While much of the research has focused on the abili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29ff5ec37c1322b8a631f0ab47a1ea1f
https://doi.org/10.1101/482422
https://doi.org/10.1101/482422
Autor:
Babak A. Ardekani, Kurt Masiello, Scott Gerum, David N. Guilfoyle, Csaba Vadasz, Cynthia Bleiwas, Mariko Saito, John F. Smiley, Donald A. Wilson
Publikováno v:
Alcohol. 49:571-580
Fetal alcohol spectrum disorders (FASD) are associated with cognitive and behavioral deficits, and decreased volume of the whole brain and cerebral cortex. Rodent models have shown that early postnatal treatments, which mimic ethanol toxicity in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7126cf289db3bf5a16473b713f6e756d
https://doi.org/10.1016/j.alcohol.2015.04.008
https://doi.org/10.1016/j.alcohol.2015.04.008
Autor:
Joseph A. Helpern, John LaFrancois, Xingju Nie, David N. Guilfoyle, Jens H. Jensen, Maria F. Falangola, Edward S. Hui, Heather R. Collins, Scott Gerum, Ali Tabesh, Caixia Hu
Publikováno v:
NMR in Biomedicine. 27:948-957
The cuprizone mouse model is well established for studying the processes of both demyelination and remyelination in the corpus callosum, and it has been utilized together with diffusion tensor imaging (DTI) to investigate myelin and axonal pathology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::821589a49ab200e28eaa8e51d03c569c
https://doi.org/10.1002/nbm.3140
https://doi.org/10.1002/nbm.3140
Publikováno v:
Journal of Molecular Neuroscience. 53:135-141
Glutamatergic neurotransmission in the brain is modulated by metabotropic glutamate receptors (mGluR). In recent studies, we identified a cis-regulated variant of a gene (Grm7) which codes for mGluR subtype 7 (mGluR7), a presynaptic inhibitory recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0a53d3a759092fc7a0687d9df9ae652
https://doi.org/10.1007/s12031-013-0211-5
https://doi.org/10.1007/s12031-013-0211-5