Zobrazeno 1 - 10
of 18
pro vyhledávání: '"David Mzinza"'
Autor:
Marah G. Chibwana, Thandeka Moyo-Gwete, Gaurav Kwatra, Jonathan Mandolo, Tandile Hermanaus, Thopisang Motlou, Nonkululeko Mzindle, Frances Ayres, Mphatso Chaponda, Godwin Tembo, Percy Mwenechanya, Ndaona Mitole, Chisomo Jassi, Raphael Kamng’ona, Louise Afran, David Mzinza, Henry C. Mwandumba, Stephen B. Gordon, Khuzwayo Jere, Shabir Madhi, Penny L. Moore, Robert S. Heyderman, Kondwani C. Jambo
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-10 (2022)
Abstract Background Binding and neutralising anti-Spike antibodies play a key role in immune defence against SARS-CoV-2 infection. Since it is known that antibodies wane with time and new immune-evasive variants are emerging, we aimed to assess the d
Externí odkaz:
https://doaj.org/article/b08b88ed1702406caaffe4634de9775e
Autor:
Shuyong Zhu, Nancy Stanslowsky, Jorge Fernández-Trillo, Tamrat M. Mamo, Pengfei Yu, Norman Kalmbach, Birgit Ritter, Reto Eggenschwiler, Werner J.D. Ouwendijk, David Mzinza, Likai Tan, Andreas Leffler, Michael Spohn, Richard J.P. Brown, Kai A. Kropp, Volkhard Kaever, Teng-Cheong Ha, Pratibha Narayanan, Adam Grundhoff, Reinhold Förster, Axel Schambach, Georges M.G.M. Verjans, Manuela Schmidt, Andreas Kispert, Tobias Cantz, Ana Gomis, Florian Wegner, Abel Viejo-Borbolla
Publikováno v:
Stem Cell Research, Vol 56, Iss , Pp 102535- (2021)
Somatosensory low threshold mechanoreceptors (LTMRs) sense innocuous mechanical forces, largely through specialized axon termini termed sensory nerve endings, where the mechanotransduction process initiates upon activation of mechanotransducers. In h
Externí odkaz:
https://doaj.org/article/c19fa53982d04aa9802dafcb4602256b
Autor:
Leonard Mvaya, Andrew Mwale, Annemarie Hummel, Joseph Phiri, Raphael Kamng'ona, David Mzinza, Elizabeth Chimbayo, Rose Malamba, Anstead Kankwatira, Henry C. Mwandumba, Kondwani C. Jambo
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
HIV-infected adults are at an increased risk to lower respiratory tract infections (LRTIs). CD8+CD161++TCRvα7.2+ T cells are an innate-like T cell subset that are thought to play an important role in early defense against pathogens in the respirator
Externí odkaz:
https://doaj.org/article/f48f3c96b32e4a81af2e1395af31102e
Autor:
Enoch Sepako, Sarah J Glennie, Kondwani C Jambo, David Mzinza, Oluwadamilola H Iwajomo, Dominic Banda, Joep J van Oosterhout, Neil A Williams, Stephen B Gordon, Robert S Heyderman
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100640 (2014)
HIV-infected African adults are at a considerably increased risk of life-threatening invasive pneumococcal disease (IPD) which persists despite antiretroviral therapy (ART). Defects in naturally acquired pneumococcal-specific T-cell immunity have bee
Externí odkaz:
https://doaj.org/article/37a0b4a529be46a3a2dca5ed0b423d42
Autor:
Kondwani C Jambo, Enoch Sepako, Sarah J Glennie, David Mzinza, Neil A Williams, Stephen B Gordon, Robert S Heyderman
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38628 (2012)
Seasonal influenza has been associated with greater morbidity and mortality in AIDS patients. Highly-active antiretroviral therapy (HAART) has led to some reduction in influenza-related complications but the nature of naturally-acquired T-cell immuni
Externí odkaz:
https://doaj.org/article/2927e215f38e4cdb8961e0a2146e5efa
Autor:
Sarah J Glennie, Enoch Sepako, David Mzinza, Visopo Harawa, David J C Miles, Kondwani C Jambo, Stephen B Gordon, Neil A Williams, Robert S Heyderman
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25610 (2011)
Invasive pneumococcal disease (IPD) is a leading cause of morbidity and mortality in HIV-infected African adults. CD4 T cell depletion may partially explain this high disease burden but those with relatively preserved T cell numbers are still at incr
Externí odkaz:
https://doaj.org/article/fbe83137189c4250bec91b8e04ad2d3b
Publikováno v:
Current Opinion in Infectious Diseases. 34:25-33
PURPOSE OF REVIEW People living with HIV (PLWH) are commonly coinfected with Mycobacterium tuberculosis, particularly in high-transmission resource-limited regions. Despite expanded access to antiretroviral therapy and tuberculosis (TB) treatment, TB
Autor:
Kondwani C. Jambo, Davide Pisu, David Mzinza, Gabrielle Lê-Bury, Monique E. Theriault, David V Mhango, Amit Singhal, Lu Huang, Steven C. Mitini-Nkhoma, Agnes E Lakudzala, Bernett Lee, Vipin Narang, David G. Russell, Henry C. Mwandumba
Publikováno v:
The Journal of Experimental Medicine
Through scRNA-seq and ATAC-seq, Pisu et al. characterize specific lung macrophage subsets that either restrict or promote M. tuberculosis growth. Comparable macrophage populations are present in the human airways, and cells show evidence of epigeneti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::609b1f0634bad27450712873b9527f39
https://archive.lstmed.ac.uk/18616/1/Mwandumba_Jambo_JEM2021.pdf
https://archive.lstmed.ac.uk/18616/1/Mwandumba_Jambo_JEM2021.pdf
Autor:
Christine Mandalasi, Elizabeth Chimbayo, Agness Lakudzala, David Mzinza, Henry C. Mwandumba, David V Mhango, Kondwani C. Jambo, Steven C. Mitini-Nkhoma, Aaron P. Chirambo, Dumizulu L. Tembo
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Tuberculosis (TB) remains a challenging global health concern and claims more than a million lives every year. We lack an effective vaccine and understanding of what constitutes protective immunity against TB to inform rational vaccine design. Moreov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb052b073773d326f77c70246ba1ee5c
Autor:
Raphael Kamng'ona, Elizabeth Chimbayo, Andrew Mwale, Leonard Mvaya, Annemarie Hummel, Joseph Phiri, Anstead M. Kankwatira, David Mzinza, Rose Malamba, Kondwani C. Jambo, Henry C. Mwandumba
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology, Vol 10 (2019)
HIV-infected adults are at an increased risk to lower respiratory tract infections (LRTIs). CD8+CD161++TCRvα7.2+ T cells are an innate-like T cell subset that are thought to play an important role in early defense against pathogens in the respirator