Zobrazeno 1 - 5
of 5
pro vyhledávání: '"David Molina-Granada"'
Autor:
David Molina-Granada, Emiliano González-Vioque, Marris G. Dibley, Raquel Cabrera-Pérez, Antoni Vallbona-Garcia, Javier Torres-Torronteras, Leonid A. Sazanov, Michael T. Ryan, Yolanda Cámara, Ramon Martí
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-16 (2022)
Mitochondrial dGTP is mostly bound to an accessory subunit of complex I of the mitochondrial respiratory chain, which may reveal a mechanism linking mitochondrial dNTP availability and oxidative metabolism.
Externí odkaz:
https://doaj.org/article/c2e314fb4cc24c139f22530a243441eb
Autor:
Cora Blázquez-Bermejo, David Molina-Granada, Ferran Vila-Julià, Daniel Jiménez-Heis, Xiaoshan Zhou, Javier Torres-Torronteras, Anna Karlsson, Ramon Martí, Yolanda Cámara
Publikováno v:
EBioMedicine, Vol 46, Iss , Pp 342-355 (2019)
Background: Thymidine kinase 2 (TK2) catalyses the phosphorylation of deoxythymidine (dThd) and deoxycytidine (dCtd) within mitochondria. TK2 deficiency leads to mtDNA depletion or accumulation of multiple deletions. In patients, TK2 mutations typica
Externí odkaz:
https://doaj.org/article/786d6e325102429ebcb0aa282446d918
Autor:
Yolanda Cámara, Ferran Vila-Julià, David Molina-Granada, Maria Jesús Melià, Javier Torres-Torronteras, Miguel Molina-Berenguer, Ramon Martí, Elena García-Arumí, Javier Ramón
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 6447, p 6447 (2021)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Scientia
International Journal of Molecular Sciences, Vol 22, Iss 6447, p 6447 (2021)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Scientia
Esgotament; Teràpia gènica; Mitocondris Mitochondria; Depletion; Gene therapy Agotamiento; Terapia génica; Mitocondrias Mitochondrial DNA depletion and multiple deletions syndromes (MDDS) constitute a group of mitochondrial diseases defined by dys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a05d416ac82094cae00451c40ad52ab
http://europepmc.org/articles/PMC8234938
http://europepmc.org/articles/PMC8234938
Autor:
Ramon Martí, Raquel Cabrera-Pérez, Anne Lombès, David Molina-Granada, Javier Torres-Torronteras, Xavier de la Cruz, Elena García-Arumí, Cora Blázquez-Bermejo, Lidia Carreño-Gago, Javier Ramón, Miguel Martín, Cristina Domínguez-González, Josu Aguirre, Yolanda Cámara
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33(6)
Polymerase γ catalytic subunit (POLG) gene encodes the enzyme responsible for mitochondrial DNA (mtDNA) synthesis. Mutations affecting POLG are the most prevalent cause of mitochondrial disease because of defective mtDNA replication and lead to a wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dad9b18c9800c45fe3dda3cc701df9d9
https://pubmed.ncbi.nlm.nih.gov/30848931
https://pubmed.ncbi.nlm.nih.gov/30848931
Autor:
Anna Karlsson, Ramon Martí, Xiaoshan Zhou, Ferran Vila-Julià, David Molina-Granada, Javier Torres-Torronteras, Yolanda Cámara, Daniel Jiménez-Heis, Cora Blázquez-Bermejo
Publikováno v:
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
EBioMedicine
Scientia
Universitat Autònoma de Barcelona
EBioMedicine
Scientia
Deoxycytidine; Deoxynucleoside therapy; Encephalomyopathy Desoxicitidina; Terapia basada en desoxinucleósido; Encefalomiopatía Desoxicitidina; Teràpia basada en desoxinucleòsid; Encefalomiopatia BACKGROUND: Thymidine kinase 2 (TK2) catalyses the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9d9c527846a421620e33a8e62ea56f2
https://ddd.uab.cat/record/226556
https://ddd.uab.cat/record/226556
