Zobrazeno 1 - 8
of 8
pro vyhledávání: '"David Mitzner"'
Autor:
Michael Henkel, David Mitzner, Peter Henklein, Franz-Josef Meyer-Almes, Anna Moroni, Mattia L Difrancesco, Leonhard M Henkes, Michael Kreim, Stefan M Kast, Ulrich Schubert, Gerhard Thiel
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11112 (2010)
BackgroundPB1-F2 is a proapoptotic influenza A virus protein of approximately 90 amino acids in length that is located in the nucleus, cytosol and in the mitochondria membrane of infected cells. Previous studies indicated that the molecule destabiliz
Externí odkaz:
https://doaj.org/article/d750ef13fc514eb9ab39d492520fe55b
Autor:
André Eissmann, Victor Wray, Uwe Tessmer, Torgils Fossen, Karsten Bruns, Ulrich S. Schubert, Alok Sharma, David Mitzner, Nicole Studtrucker, Peter Henklein, René Röder
Publikováno v:
Journal of Biological Chemistry. 282:353-363
Recently, a novel 87-amino acid influenza A virus protein with proapoptotic properties, PB1-F2, has been reported that originates from an alternative reading frame in the PB1 polymerase gene and is encoded in most known human influenza A virus isolat
Autor:
Karsten Bruns, Sara Marie Øie Solbak, Alok Sharma, Friedrich Hahn, Petra Henklein, David Mitzner, Anni Vedeler, Peter Henklein, Ulrich S. Schubert, Torgils Fossen, René Röder, Rebekka Niebert, Victor Wray
Publikováno v:
Biochimica et biophysica acta. 1834(2)
The proapoptotic influenza A virus PB1-F2 protein contributes to viral pathogenicity and is present in most human and avian influenza isolates. The structures of full-length PB1-F2 of the influenza strains Pandemic flu 2009 H1N1, 1918 Spanish flu H1N
Autor:
Oliver Planz, David Mitzner, Eva-Katharina Pauli, Ralf Kircheis, Emanuel Haasbach, Ulrich S. Schubert, Robert Spranger
Publikováno v:
Antiviral research. 91(3)
The appearance of highly pathogenic avian influenza A viruses of the H5N1 subtype being able to infect humans and the 2009 H1N1 pandemic reveals the urgent need for new and efficient countermeasures against these viruses. The long-term efficacy of cu
Autor:
Franz-Josef Meyer-Almes, Stefan M. Kast, Mattia L. DiFrancesco, Leonhard Henkes, Michael Henkel, Gerhard Thiel, Michael Kreim, Peter Henklein, Ulrich S. Schubert, Anna Moroni, David Mitzner
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11112 (2010)
PLoS ONE; Vol 5
PLoS ONE
PLoS ONE; Vol 5
PLoS ONE
BackgroundPB1-F2 is a proapoptotic influenza A virus protein of approximately 90 amino acids in length that is located in the nucleus, cytosol and in the mitochondria membrane of infected cells. Previous studies indicated that the molecule destabiliz
Autor:
Karsten Bruns, Alok Sharma, David Mitzner, Ulrich S. Schubert, Sabine Eva Dudek, Ludmilla Wixler, Igor Mazur, Josef Wissing, Stephan Ludwig, Nicole Studtrucker, Victor Wray, Peter Henklein, Darisuren Anhlan, Lothar Jänsch
Publikováno v:
Cellular microbiology. 11(10)
The 11(th) influenza A virus (IAV) protein PB1-F2 is encoded by an alternative reading frame of the PB1 polymerase gene and found in the nucleus, cytosol and at the mitochondria of infected cells, the latter is consistent with experimental evidence f
Autor:
David Mitzner, Igor Mazur, Ludmilla Wixler, Ulrich S. Schubert, Darisuren Anhlan, Stephan Ludwig
Publikováno v:
Cellular microbiology. 10(5)
The 11th influenza A virus protein PB1-F2 was previously shown to enhance apoptosis in response to cytotoxic stimuli. The 87 amino acid protein that is encoded by an alternative reading frame of the PB1 polymerase gene was described to localize to mi
Autor:
Peter Henklein, René Röder, Karsten Bruns, Ole Horvli, Torgils Fossen, David Mitzner, Tove Ragna Reksten, Ulrich S. Schubert, Petra Henklein, Victor Wray, Arnt J. Raae, Sara Marie Øie Solbak
Publikováno v:
BMC Structural Biology, Vol 10, Iss 1, p 31 (2010)
BMC Structural Biology
BMC Structural Biology
Background Cyclophilin A (CypA) represents a potential target for antiretroviral therapy since inhibition of CypA suppresses human immunodeficiency virus type 1 (HIV-1) replication, although the mechanism through which CypA modulates HIV-1 infectivit