Zobrazeno 1 - 10
of 1 034
pro vyhledávání: '"David Mitchell"'
Autor:
Pang-ning Teng, Joshua P. Schaaf, Tamara Abulez, Brian L. Hood, Katlin N. Wilson, Tracy J. Litzi, David Mitchell, Kelly A. Conrads, Allison L. Hunt, Victoria Olowu, Julie Oliver, Fred S. Park, Marshé Edwards, AiChun Chiang, Matthew D. Wilkerson, Praveen-Kumar Raj-Kumar, Christopher M. Tarney, Kathleen M. Darcy, Neil T. Phippen, G. Larry Maxwell, Thomas P. Conrads, Nicholas W. Bateman
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109198- (2024)
Summary: Numerous multi-omic investigations of cancer tissue have documented varying and poor pairwise transcript:protein quantitative correlations, and most deconvolution tools aiming to predict cell type proportions (cell admixture) have been devel
Externí odkaz:
https://doaj.org/article/87a62e3f792e48a18b676967436cc62a
Autor:
Alaa Bamahmud MD, Mohamed El-Sherbiny MD, Roman Jednak MD, Karl Muchantef MD, Sharon Abish MD, David Mitchell MD, Catherine Vezina MD, Indra R. Gupta MD
Publikováno v:
Canadian Journal of Kidney Health and Disease, Vol 10 (2023)
Rationale: Imatinib is used in the treatment of Philadelphia chromosome positive (Ph+) leukemias and has been reported to have a direct effect on bone physiology. Presentation: To report on a child with Ph+ acute lymphoblastic leukemia who presented
Externí odkaz:
https://doaj.org/article/47fe652d1c2042efb25776c4cfef9081
Autor:
Abdulhakim Bake, Qi Zhang, Cong Son Ho, Grace L. Causer, Weiyao Zhao, Zengji Yue, Alexander Nguyen, Golrokh Akhgar, Julie Karel, David Mitchell, Zeljko Pastuovic, Roger Lewis, Jared H. Cole, Mitchell Nancarrow, Nagarajan Valanoor, Xiaolin Wang, David Cortie
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-8 (2023)
Topological edge states offer the prospect of dissipationless transport for nanoelectronics, but a precise method to spatially engineer such nanoscale conducting channels is still lacking. Here, the authors demonstrate patterning of topological bound
Externí odkaz:
https://doaj.org/article/884cc2e24fc94507958d78e6aba79f88
Autor:
Jessica E. Marris, Andrew Perfors, David Mitchell, Wayland Wang, Mark W. McCusker, Timothy John Haynes Lovell, Robert N. Gibson, Frank Gaillard, Piers D. L. Howe
Publikováno v:
Cognitive Research, Vol 8, Iss 1, Pp 1-18 (2023)
Abstract Recent work has shown that perceptual training can be used to improve the performance of novices in real-world visual classification tasks with medical images, but it is unclear which perceptual training methods are the most effective, espec
Externí odkaz:
https://doaj.org/article/33718076258e48a4b46f9ba2e697e9ea
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 12, Pp 2888-2898 (2022)
Abstract The pharmacometric analysis of the double‐blind, randomized, phase II study (NCT02975349) investigating the safety and efficacy of evobrutinib, explored exposure–response relationships and suitable dosing regimens of evobrutinib for rela
Externí odkaz:
https://doaj.org/article/1574bc86c94149c2ace8e09bd96f649c
Population pharmacokinetic and pharmacodynamic modeling of evobrutinib in healthy adult participants
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 12, Pp 2899-2908 (2022)
Abstract Evobrutinib, a Bruton's tyrosine kinase (BTK) inhibitor, has shown therapeutic potential in relapsing multiple sclerosis. This analysis aimed to develop pharmacokinetic (PK) and pharmacodynamic (PD; BTK occupancy [BTKO]) models of evobrutini
Externí odkaz:
https://doaj.org/article/64656ea9310f4b0f898d8fa0c197deb8
Publikováno v:
Journal of Vascular Surgery Cases and Innovative Techniques, Vol 8, Iss 2, Pp 146-150 (2022)
A previously well, independent 20-year-old man presented with a 4-day history of progressive left lower limb pain with associated phlegmasia cerulea dolens. Duplex venous ultrasound examination and computed tomography venogram revealed extensive deep
Externí odkaz:
https://doaj.org/article/369e03bc756b47f8abdbb8cde4c160ec
Autor:
Andrii Voshchepynets, Oleksiy V. Agapitov, Lynn Wilson III, Vassilis Angelopoulos, Samer T. Alnussirat, Michael Balikhin, Myroslava Hlebena, Ihor Korol, Davin Larson, David Mitchell, Christopher Owen, Ali Rahmati
Publikováno v:
The Astrophysical Journal Letters, Vol 956, Iss 1, p L4 (2023)
We present the results of processing the effects of the powerful gamma-ray burst GRB221009A captured by the charged particle detectors (electrostatic analyzers and solid-state detectors) on board spacecraft at different points in the heliosphere on 2
Externí odkaz:
https://doaj.org/article/a726254acc144e4c97ed2e8451f0bcb6
Autor:
Mitchell K Byrne, Bróna Nic Giolla Easpaig, Richard Gray, Rebecca Creek, Martin Jones, Ellie Brown, David Mitchell, Jianxia Zhai, Jing-Yu Tan, Shaun Denis, Daniel Bressington
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0280559 (2023)
BackgroundTheoretically, behavioural activation may have a valuable role to play in the treatment of depression among young people with emerging/early psychosis, however we lack trial evidence concerning its acceptability and feasibility. This study
Externí odkaz:
https://doaj.org/article/a6232fb135b54152b571ff3358196551
Autor:
Holger Scheible, Martin Dyroff, Annick Seithel‐Keuth, Eleanor Harrison‐Moench, Nadra Mammasse, Andreas Port, Angelika Bachmann, Jennifer Dong, Jan Jaap vanLier, William Tracewell, David Mitchell
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 6, Pp 2420-2430 (2021)
Abstract The highly selective, covalent Bruton’s tyrosine kinase inhibitor evobrutinib is under investigation for treatment of patients with multiple sclerosis (MS). Early clinical studies in healthy participants and patients with relapsing MS indi
Externí odkaz:
https://doaj.org/article/489421b638da46dbad0cbcea83c71c6e