Zobrazeno 1 - 10
of 64
pro vyhledávání: '"David Middlemiss"'
Publikováno v:
Proceedings of the Institution of Civil Engineers - Maritime Engineering. 167:116-124
The determination of sediment loss rates from dredging activities is important for quantifying the potential impact on the surrounding physical and biological environment. This paper describes an improved method for measuring and analysing data to de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::018a419b7129ec71b92ac99128a30eef
https://doi.org/10.1680/maen.13.00018
https://doi.org/10.1680/maen.13.00018
The 1-exo proton of tricarbonyl-4-exo-methyl- or tricarbonyl-4-exo-ethyl-2-methyl-1,2,3,4-tetrahydroisoquinolinechromium (6) and (7) can be regio- and stereo-selectively removed by t-butyl-lithium and replaced with a variety of electrophiles to give
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83448fb5a6fcf62c322af3eee32738f1
https://doi.org/10.1039/p19870000689
https://doi.org/10.1039/p19870000689
The enantiomerically pure iron acyl complex R-(-)-[(η5-C5H5)Fe(CO)(PPh3)- COCH2O(\{{1R,2S,5R]menthyl\}})] represents a source of homochiral formyl anion equivalent applicable to the synthesis of enantiomerically pure α-hydroxy acetals from aldehyde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ab1a1deac9a97d74f18b3a9554269be
https://doi.org/10.1016/s0040-4039(00)99172-x
https://doi.org/10.1016/s0040-4039(00)99172-x
Acid-promoted cyclisation of (+)-(R)-N-(3,4-dimethoxybenzyl)halostachine tricarbonylchromium at –20 °C is highly stereoselective, proceeding with retention of configuration, to yield, after removal of the tricarbonylchromium unit, homochiral (+)-(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fdb07bf2d97bd4712eb2c4f0a0816e5
https://ora.ox.ac.uk/objects/uuid:87177752-f0a1-477f-8f67-6252ddd637ab
https://ora.ox.ac.uk/objects/uuid:87177752-f0a1-477f-8f67-6252ddd637ab
Autor:
Craig L. Goodfellow, Stephen G. Davies, Alan Naylor, Steven J. Coote, David Middlemiss, K. H. Sutton
(−)-(1 S ,2 S )-( N ,O-Dimethylephedrine)tricarbonyl chromium(0) (6) and (−)-(1 S ,2 R )-( N ,O-dimethylpseudoephedrine)tricarbonylchiromium(0) ( 22 ) undergo completely stereoselective ortho deprotonation upon treatment with alkyllithium base, f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3b2cf9c887daebd20ccb4efc7af5e4b
https://doi.org/10.1016/s0957-4166(00)80447-4
https://doi.org/10.1016/s0957-4166(00)80447-4
Autor:
Luzheng Xue, Mark Richard Ashton, Frederick Arthur Brookfield, Shân L. Gyles, Mark Cowley Whittaker, Roy Pettipher, Richard Edward Armer, Edward Andrew Boyd, Michael G. Hunter, Christopher James Brennan, Philip Andrew Hay, David Middlemiss, Lucien Gazi
Publikováno v:
Journal of Medicinal Chemistry. 48:6174-6177
Prostaglandin D2 (PGD2) acting at the CRTH2 receptor (chemoattractant receptor-homologous molecule expressed on Th2 cells) has been linked with a variety of allergic and other inflammatory diseases. We describe a family of indole-1-sulfonyl-3-acetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff642328060fa8adb52a26d21e76d9bf
https://doi.org/10.1021/jm050519b
https://doi.org/10.1021/jm050519b
Publikováno v:
Synlett. 2000:1415-1418
The use of a high powered ultrasound source in promoting the Pauson-Khand reaction has been extensively investigated. In conjunction with amines and N-oxide techniques, this developed methodology allows efficient access to a range of cyclopentenones
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da33bd112ecb7c073e3ce3dfac69e7ad
https://doi.org/10.1055/s-2000-7639
https://doi.org/10.1055/s-2000-7639
Autor:
William J. Kerr, Nicola Murdoch Heron, David Middlemiss, Sharon McKendry, John J. Caldwell, Joseph P. A. Harrity
Publikováno v:
Tetrahedron Letters. 40:3481-3484
The reaction of chromium aryl(alkoxy)carbenes with propargylic alcohols has been investigated under dry state adsorption and ultrasound conditions. When compared to the corresponding thermal processes, the developed sonication reactions afford good y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5fabefe90a021a41a0ed3a9dec2b0b6
https://doi.org/10.1016/s0040-4039(99)00429-3
https://doi.org/10.1016/s0040-4039(99)00429-3
Publikováno v:
Journal of Organometallic Chemistry. 519:93-101
A range of diastereomeric alkynepentacarbonyldicobalt complexes containing the (R)-(+)-Glyphos ligand have been prepared in moderate to good yields under standard thermal conditions. Additionally, novel tertiary amine N-oxide mediated reactions have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb38e8cab7f6d5cc7045c4a6862d9bb4
https://doi.org/10.1016/s0022-328x(96)06174-8
https://doi.org/10.1016/s0022-328x(96)06174-8
A convenient procedure for the solution phase preparation of 2-aminothiazole combinatorial libraries
Autor:
R. Storer, David Middlemiss, Stephen P. Watson, Nicholas Bailey, Duncan Bruce Judd, Anthony W. Dean
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 6:1409-1414
A convenient procedure for the solution phase preparation of 2-aminothiazole combinatorial libraries is described. The library preparation is simple, practical, and effective, generating compounds based around a known pharmacophore in high yield and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fb115a85bbfa8fef8b1896df7a433a9
https://doi.org/10.1016/0960-894x(96)00241-7
https://doi.org/10.1016/0960-894x(96)00241-7