Zobrazeno 1 - 10
of 33
pro vyhledávání: '"David Megirian"'
Autor:
Beverly Bishop, David Megirian
Publikováno v:
Adaptive Medicine. 6:73-79
We hypothesized that chronic hypoxia's disruption of the regulation of body temperature (T_b), activity (L_a) and their respective circadian oscillations in cohorts of rats, caged separately from each other, differs significantly between two cohorts,
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 286:R1129-R1137
Upper airway dilator activity during sleep appears to be diminished under conditions of enhanced sleep propensity, such as after sleep deprivation, leading to worsening of obstructive sleep apnea (OSA). Non-rapid eye movement (NREM) sleep propensity
Publikováno v:
Medicine and Science in Sports and Exercise. 34:251-257
Purpose During inspiration, recruitment of the intrinsic laryngeal muscles (ILM) reduces the inspiratory load on the ventilatory pump muscles. The purpose of our study was to determine 1) whether the diaphragm adapts to denervation of the ILM, and 2)
Autor:
Klaus I. Matthaei, Kim L. Kelleher, Anna J. Reynolds, Katharina Heydon, David Megirian, Selena E. Bartlett, Kwong-Joo Leck, Ian A. Hendry, Albert S. Mellick
Publikováno v:
Brain Research. 870:10-19
Our laboratory has generated a mouse deficient in the alpha (α) subunit of the G protein, Gz, (Gzα) gene and we have examined the involvement of Gzα in spinal and supraspinal analgesia and tolerance mechanisms. Spinal analgesia was tested by the r
Autor:
David Megirian
Publikováno v:
Physiology. 30:170-170
Most mammals are acknowledged as social beings. Rats are as much social creatures as are humans: rats too live in aggregates. It is reasonable to assume that its members communicate with each other in distinctive and diverse ways. Here, the emphasis
Autor:
Maree T. Smith, Ian A. Hendry, Joan Holgate, Kwong-Joo Leck, Kim L. Powell, David Megirian, Klaus I. Matthaei, Selena E. Bartlett
Publikováno v:
Neuropharmacology. 46(6)
The Mechanism Underlying the development of tolerance to morphine, is still incompletely understood. Morphine binds to opioid receptors, Which in turn activates downstream second messenger cascades through heterotrimeric guanine nucleotide binding pr
Publikováno v:
The American journal of physiology. 275(2)
We measured body temperature (Tb) and ventilatory and metabolic variables in lean ( n = 8) and obese ( n = 8) Zucker rats. Measurements were made while rats breathed air, 4% CO2, and 10% O2. Under control conditions, Tbin obese rats was always less t
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 84(1)
Megirian, David, Jacek Dmochowski, and Gaspar A. Farkas. Mechanism controlling sleep organization of the obese Zucker rat. J. Appl. Physiol. 84(1): 253–256, 1998.—We tested the hypothesis that the obese ( fa/fa) Zucker rat has a sleep organizatio
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 83(4)
Gosselin, Luc E., David Megirian, Joshua Rodman, Donna Mueller, and Gaspar A. Farkas. Respiratory muscle reserve in rats during heavy exercise. J. Appl. Physiol. 83(4): 1405–1409, 1997.—The extent to which the respiratory pump muscles limit maxim
Publikováno v:
Respiration physiology. 97(1)
To estimate the contribution of the parasternal intercostals to rib elevation during quiet breathing, parasternal intramuscular pressure, Pim, in the fourth interspace and displacement of the rib just below were measured in eight supine anesthetized